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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS09870 [old locus tag: NWMN_1752 ]
  • pan locus tag?: SAUPAN004796000
  • symbol: NWMN_RS09870
  • pan gene symbol?: tnp3
  • synonym:
  • product: ISL3 family transposase IS1181

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS09870 [old locus tag: NWMN_1752 ]
  • symbol: NWMN_RS09870
  • product: ISL3 family transposase IS1181
  • replicon: chromosome
  • strand: +
  • coordinates: 1954178..1955497
  • length: 1320
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (1954178..1955497) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGTGTAATGATACCTTAGAATTACTAAGAATAAAAGATGAAAATATAAAATATATAAAC
    CAAGAAATTGACGTCATTATCAAAGGAAAAAAAGCAACAGTGGTTAATGCTGTACTAACG
    TATAAGCCTTCGGCCTGTTATTGTTGTGGAGTTAAAAATGAAGGACAAATTCATAAACAT
    GGTAAGCGTGTTTCTCGTATTACTTTACTTAAAACTCAAGGGTATAACACATACCTCAAC
    TTAGCTAAACAACGTTTTAAATGCTTAGAATGCAATGGCACTTTTACTGCTAAAACGTCA
    ATTGTTGATGAGTCGTGTTTTATCTCAAGATGTGTTACTCAAAAAGTTATAGAAGAAGCT
    ACTAAAGTTAAAACAGAGATTGATACTGCAGAAGATAACTGTATCTCTCCATCTACTGTA
    AGTCGTATTAGAACTAAAGCGGCTAATTCATTACGAATTAAACCCTTTAATTGTTTGCCA
    GAACACATCGCTATGGATGAATTTAAAAGCGTTAAAAATGTAACTGGATCAATGAGTTTC
    ATTTTTATAGATAATGATACTCATGATGTTATAGATATTTTAGAAAATAGAACTACAAGA
    TTCTTGCGTGCCTATTTCGAGCGATTCGATTTAAAAAATCGACAACAAGTTAAGACGGTT
    ACTATTGACATGTATGAACCCTATGTCCGATTATTTCGCGACCTATTTCCTAATGCAGCT
    ATTATTTTTGACAGATTCCATATCGTTCAACATTTAAATAGAGAACTTAATAAGTATCGT
    GTACAAGTTATGAATGAATACCGTAATAAAAAAGGACCTGATTATACAATTTTTAAGAAT
    AACTGGAAAGTCCTATTGATGGATACTAGTAAAACCATATTTAGTAAATACAGATGGAAT
    AAATCTTTTAAGGCTTATAAACGCTCATCTGACATTGTAGAATTCATGCTTTCAAAAGAC
    GATATACTACGACACTCCTACGAACTTGTCCAAGGATTACGAAAAGACCTAAGGTTATGT
    AATTGGCCTAAATTTATTAATCGTTTAAATTCAGTTAGTAAAAAGTCTGTGAGTAAGGGT
    GTATGGAAAGCGGTTAAATATTATAGAAAACATCAAAGGATGTTAAGAAATACAATTTAT
    TACCCAGCATTTAATAATGGTGCTATAGAAGGAATTAATAATAAGATAAAATTAATCAAG
    CGAATTTCTTTTGGTTACAGAAATTTCAACAACTTTAAAGCACGTATAATGATGATTTTC
    AGCTTGTACAAAGGAGAAAAAAAGAAGACAACCAAGCCCAATAATGGACTGGCCGCCTAA
    60
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    1020
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    1140
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    1260
    1320

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS09870 [old locus tag: NWMN_1752 ]
  • symbol: NWMN_RS09870
  • description: ISL3 family transposase IS1181
  • length: 439
  • theoretical pI: 10.3811
  • theoretical MW: 51524.6
  • GRAVY: -0.489066

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Cellular processesCellular processesDetoxificationS-(hydroxymethyl)glutathione synthase (TIGR02820; EC 4.4.1.22; HMM-score: 16.5)
    MetabolismCentral intermediary metabolismOne-carbon metabolismS-(hydroxymethyl)glutathione synthase (TIGR02820; EC 4.4.1.22; HMM-score: 16.5)
  • TheSEED:
  • PFAM:
    RNase_H (CL0219) DDE_Tnp_ISL3; Transposase (PF01610; HMM-score: 172.2)
    Zn_Beta_Ribbon (CL0167) zf-ISL3; zinc-finger of transposase IS204/IS1001/IS1096/IS1165 (PF14690; HMM-score: 42.4)
    HTH (CL0123) HTH_Tnp_ISL3; Helix-turn-helix domain of transposase family ISL3 (PF13542; HMM-score: 20.6)
    no clan definedDUF3795; Protein of unknown function (DUF3795) (PF12675; HMM-score: 10.3)
    DUF4163; Domain of unknown function (DUF4163) (PF13739; HMM-score: 9.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.136
    • Ymax_pos: 53
    • Cmax: 0.106
    • Cmax_pos: 48
    • Smax: 0.231
    • Smax_pos: 45
    • Smean: 0.121
    • D: 0.13
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 487723914 NCBI
  • RefSeq: WP_001808146 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MCNDTLELLRIKDENIKYINQEIDVIIKGKKATVVNAVLTYKPSACYCCGVKNEGQIHKHGKRVSRITLLKTQGYNTYLNLAKQRFKCLECNGTFTAKTSIVDESCFISRCVTQKVIEEATKVKTEIDTAEDNCISPSTVSRIRTKAANSLRIKPFNCLPEHIAMDEFKSVKNVTGSMSFIFIDNDTHDVIDILENRTTRFLRAYFERFDLKNRQQVKTVTIDMYEPYVRLFRDLFPNAAIIFDRFHIVQHLNRELNKYRVQVMNEYRNKKGPDYTIFKNNWKVLLMDTSKTIFSKYRWNKSFKAYKRSSDIVEFMLSKDDILRHSYELVQGLRKDLRLCNWPKFINRLNSVSKKSVSKGVWKAVKYYRKHQRMLRNTIYYPAFNNGAIEGINNKIKLIKRISFGYRNFNNFKARIMMIFSLYKGEKKKTTKPNNGLAA

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS09870 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]