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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus Newman
  • locus tag: NWMN_RS11130 [old locus tag: NWMN_1929 ]
  • pan locus tag?: SAUPAN005193000
  • symbol: NWMN_RS11130
  • pan gene symbol?:
  • synonym:
  • product: succinyl-diaminopimelate desuccinylase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: NWMN_RS11130 [old locus tag: NWMN_1929 ]
  • symbol: NWMN_RS11130
  • product: succinyl-diaminopimelate desuccinylase
  • replicon: chromosome
  • strand: +
  • coordinates: 2135868..2137091
  • length: 1224
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_009641 (2135868..2137091) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
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    841
    901
    961
    1021
    1081
    1141
    1201
    ATGACAACTTTTAGTGAAAAAGAAAAAATTCAATTACTAGCAGATATTGTTGAACTACAA
    ACTGAAAATAATAATGAAATAGACGTTTGTAATTATTTAACAGATTTATTCGACAAGTAC
    GATATTAAATCTGAAATTTTGAAAGTTAATGAACACCGCGCCAATATCGTTGCAGAAATC
    GGTAACGGCTCACCTATACTCGCATTGAGTGGTCATATGGATGTTGTTGATGCAGGAAAT
    CAAGATAATTGGTCATATCCCCCTTTTCAACTGACAGAAAAAGATGGCAAATTATATGGC
    CGAGGCACTACAGATATGAAAGGCGGTTTAATGGCTTTGGTCGTATCTCTAATCGAATTA
    AAAGAACAAAATGAATTGCCTCATGGAACGATTAGATTACTGGCTACTGCTGGCGAAGAG
    AAAGAACAAGAAGGTGCCAAATTATTAGCTGATAAAGGCTATTTAGACGATGTCGATGGC
    TTAATTATTGCTGAACCAACTGGATCTGGAATTTATTATGCACATAAGGGGTCTATGTCA
    TGTAAAGTAACTGCAACTGGTAAAGCTGTCCATAGCTCAGTTCCATTTATTGGTGACAAT
    GCAATTGATACACTGCTTGAATTTTATAATCTATTTAAAGAAAAATATTCAGAGCTTAAA
    CAACAAGATACTAAACATGAATTAGATGTTGCGCCTATGTTCAAATCATTGATTGGAAAA
    GAAATTTCTGAAGAGGATGCAAATTATGCATCTGGTCTTACAGCTGTATGTTCGATTATA
    AATGGCGGCAAACAATTTAACTCTGTACCAGATGAAGCTTCACTTGAATTTAACGTAAGA
    CCAGTTCCTGAGTATGATAACGACTTTATAGAATCGTTTTTCCAAAATATCATTAATGAT
    GTGGATAGCAATAAGCTTTCACTCGATATTCCAAGCAATCACCGACCTGTAACAAGCGAT
    AAAAATAGCAAATTAATTACTACGATTAAAGATGTAGCTTCTAGTTATGTAGAACAAGAC
    GAAATATTTGTTTCAGCGCTTGTAGGTGCAACAGATGCCTCTAGTTTCTTAGGAGATAAT
    AAGGACAATGTTGATTTAGCCATTTTTGGACCAGGTAATCCATTAATGGCACATCAAATC
    GATGAATATATTGAAAAAGATATGTATCTGAAATATATTGATATTTTTAAAGAGGCTTCC
    ATTCAATATTTAAAAGAAAAATAA
    60
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    840
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    1020
    1080
    1140
    1200
    1224

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: NWMN_RS11130 [old locus tag: NWMN_1929 ]
  • symbol: NWMN_RS11130
  • description: succinyl-diaminopimelate desuccinylase
  • length: 407
  • theoretical pI: 4.27856
  • theoretical MW: 45097.3
  • GRAVY: -0.329975

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingProtein fateDegradation of proteins, peptides, and glycopeptidespeptidase, ArgE/DapE family (TIGR01910; EC 3.4.-.-; HMM-score: 300.7)
    MetabolismAmino acid biosynthesisGlutamate familyacetylornithine deacetylase (ArgE) (TIGR01892; EC 3.5.1.16; HMM-score: 167.9)
    MetabolismAmino acid biosynthesisAspartate familysuccinyl-diaminopimelate desuccinylase (TIGR01246; EC 3.5.1.18; HMM-score: 134.5)
    MetabolismAmino acid biosynthesisAspartate familysuccinyl-diaminopimelate desuccinylase (TIGR01900; EC 3.5.1.18; HMM-score: 122)
    putative selenium metabolism hydrolase (TIGR03526; HMM-score: 114.6)
    N-acetyl-ornithine/N-acetyl-lysine deacetylase (TIGR01902; HMM-score: 100.7)
    putative dipeptidase (TIGR01887; EC 3.4.13.-; HMM-score: 95.3)
    N-acyl-L-amino-acid amidohydrolase (TIGR01880; EC 3.5.1.14; HMM-score: 78.3)
    Genetic information processingProtein fateDegradation of proteins, peptides, and glycopeptidesamidohydrolase (TIGR01891; HMM-score: 75.6)
    Genetic information processingProtein fateDegradation of proteins, peptides, and glycopeptidesdipeptidase PepV (TIGR01886; EC 3.4.13.-; HMM-score: 51.8)
    peptidase T-like protein (TIGR01883; HMM-score: 31.3)
    Xaa-His dipeptidase (TIGR01893; EC 3.4.13.20; HMM-score: 29.2)
  • TheSEED:
  • PFAM:
    Peptidase_MH (CL0035) Peptidase_M20; Peptidase family M20/M25/M40 (PF01546; HMM-score: 137.5)
    no clan definedM20_dimer; Peptidase dimerisation domain (PF07687; HMM-score: 81.4)
    Peptidase_MH (CL0035) Peptidase_M28; Peptidase family M28 (PF04389; HMM-score: 21.6)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.112
    • Ymax_pos: 30
    • Cmax: 0.111
    • Cmax_pos: 30
    • Smax: 0.149
    • Smax_pos: 18
    • Smean: 0.105
    • D: 0.11
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446128783 NCBI
  • RefSeq: WP_000206638 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLTDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWSYPPFQLTEKDGKLYGRGTTDMKGGLMALVVSLIELKEQNELPHGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNLFKEKYSELKQQDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASIQYLKEK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • NWMN_RS11130 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]