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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0388 [new locus tag: SA_RS02225 ]
  • pan locus tag?: SAUPAN002114000
  • symbol: set12
  • pan gene symbol?: ssl8
  • synonym:
  • product: superantigen-like protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA0388 [new locus tag: SA_RS02225 ]
  • symbol: set12
  • product: superantigen-like protein
  • replicon: chromosome
  • strand: +
  • coordinates: 447914..448612
  • length: 699
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGAAATTTACAGCGATAGCTAAAGCGATATTTGTATTAGGAATATTAACAACAAGTGTA
    ATGATAACAGAAAATCAATCGGTTAATGCAAAAGGAAAGTATGAAAAAATGAACCGTTTA
    TATGATACAAACAAGTTACATCAATACTATTCAGGACCTAGTTATGAGTTAACAAATGTT
    AGTGGCCAAAGTCAAGGTTATTATGACTCTAACGTTTTGCTTTTTAACCAACAAAATCAA
    AAGTTCCAAGTATTTTTATTGGGAAAAGATGAAAATAAATACAAAGAAAAAACACATGGT
    TTAGATGTCTTTGCGGTACCAGAATTAGTAGATTTAGATGGAAGAATATTTAGTGTTAGT
    GGTGTAACGAAGAAAAACGTAAAATCAATATTTGAGTCTCTAAGAACGCCGAACTTACTA
    GTTAAAAAAATAGACGATAAAGACGGTTTTTCTATTGATGAATTTTTCTTTATTCAAAAG
    GAAGAAGTGTCATTGAAGGAACTTGATTTTAAAATAAGAAAACTGTTGATTAAAAAATAC
    AAACTGTATGAAGGGTCAGCTGATAAAGGTAGAATTGTTATTAATATGAAAGATGAAAAT
    AAGTATGAAATTGATTTAAGTGATAAATTAGATTTCGAGCGTATGGCAGATGTCATTAAT
    AGTGAACAAATTAAGAACATCGAAGTGAATTTGAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    699

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA0388 [new locus tag: SA_RS02225 ]
  • symbol: Set12
  • description: superantigen-like protein
  • length: 232
  • theoretical pI: 9.0036
  • theoretical MW: 26832.6
  • GRAVY: -0.460345

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:  
    Exotoxin 8 
  • PFAM:
    OB_enterotoxin (CL0658) SSL_OB; Staphylococcal superantigen-like OB-fold domain (PF09199; HMM-score: 109.3)
    Ant-toxin_C (CL0386) Stap_Strp_tox_C; Staphylococcal/Streptococcal toxin, beta-grasp domain (PF02876; HMM-score: 39.9)
    no clan definedAMIN; AMIN domain (PF11741; HMM-score: 13.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0
    • Extracellular Score: 10
    • Internal Helix: 1
  • LocateP: N-terminally anchored (No CS)
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: -0.17
    • Signal Peptide Possibility: 1
    • N-terminally Anchored Score: 2
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: Signal peptide length 31 aa
    • Ymax: 0.615
    • Ymax_pos: 31
    • Cmax: 0.573
    • Cmax_pos: 31
    • Smax: 0.868
    • Smax_pos: 11
    • Smean: 0.739
    • D: 0.663
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 15926105 NCBI
  • RefSeq: NP_373638 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MKFTAIAKAIFVLGILTTSVMITENQSVNAKGKYEKMNRLYDTNKLHQYYSGPSYELTNVSGQSQGYYDSNVLLFNQQNQKFQVFLLGKDENKYKEKTHGLDVFAVPELVDLDGRIFSVSGVTKKNVKSIFESLRTPNLLVKKIDDKDGFSIDEFFFIQKEEVSLKELDFKIRKLLIKKYKLYEGSADKGRIVINMKDENKYEIDLSDKLDFERMADVINSEQIKNIEVNLK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]