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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40

NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0400 [new locus tag: SA_RS02290 ]
  • pan locus tag?: SAUPAN002141000
  • symbol: lpl4
  • pan gene symbol?: lpl4
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA0400 [new locus tag: SA_RS02290 ]
  • symbol: lpl4
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 460417..461202
  • length: 786
  • essential: no DEG

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAGGGATTCAAAAAGAGTAGTATTGTACATAAGCATTATGGTGTTGAGTATTTTTATA
    ATTGGTTGTGGCAAAGGTAATGAAATAAAAGAAGACGCAAAGGAAGAACAAATCAAAAAG
    AGCTTTGCGAAAACGTTAGATATGTATCCAATCAAAAATCTCGAGGACCTATATGATAAA
    GAAGGATATCGAGATGGCGAATTTAAAAAAGGTGACAAAGGGATGTGGACGATTTACACA
    GATTTCGCCAAAAGTAATAGACCAGGTGTATTAGATAATGAAGGTATGGTTTTAAATTTG
    GATAGAAATACACGAACGGCCAAGGGATATTATTTTGTAGATACTATATATGACAATCAT
    GAAAACTCTTATAGTAAAAATTATAGAGTTGAGATGAAAAACAATAAAATTATTTTATTA
    GACAAGGTGGAAGATCAAAAACTTAAAGAAAGAATAGAAAACTTTAAATTTTTCGGACAA
    TATGCCGATTTCAAGAGTTTGAAAAGTTACAACCATGGCGACGTTTCAATTAATAGTAAT
    GTTCCAAGTTATGACGCGAAATTTAAAATGAGTAATAAAGATGAAAATGTTAAGCAATTA
    AGAAGCCGTTATAACATTCCTACTGATAAAGCTCCAATATTAAAAATGCATATTGATGGG
    GACTTAAAAGGCAGTTCCGTTGGATATAAAAAGTTAGAAATAGACTTTTCAAAAGAAGAA
    AATAGCGAATTATCAATAGTCGATTCATTAAATTTTCAACCTGCCAAAAATAAAGATGAT
    GAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    786

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA0400 [new locus tag: SA_RS02290 ]
  • symbol: Lpl4
  • description: hypothetical protein
  • length: 261
  • theoretical pI: 8.29137
  • theoretical MW: 30329.1
  • GRAVY: -0.838314

Function[edit source | edit]

  • TIGRFAM:
    Staphylococcus tandem lipoproteins (TIGR01742; HMM-score: 383)
  • TheSEED:  
    Tandem lipoprotein within Pathogenicity island 
  • PFAM:
    LolA_LolB (CL0048) DUF576; Csa1 family (PF04507; HMM-score: 371)
    and 1 more
    no clan definedFidL_like; FidL-like putative membrane protein (PF15941; HMM-score: 12.5)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • LocateP: Lipid anchored
    • Prediction by SwissProt Classification: Extracellular
    • Pathway Prediction: Sec-(SPII)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: IFIIGCG
  • SignalP: no predicted signal peptide
    • Ymax: 0.285
    • Ymax_pos: 27
    • Cmax: 0.176
    • Cmax_pos: 34
    • Smax: 0.69
    • Smax_pos: 20
    • Smean: 0.444
    • D: 0.347
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MRDSKRVVLYISIMVLSIFIIGCGKGNEIKEDAKEEQIKKSFAKTLDMYPIKNLEDLYDKEGYRDGEFKKGDKGMWTIYTDFAKSNRPGVLDNEGMVLNLDRNTRTAKGYYFVDTIYDNHENSYSKNYRVEMKNNKIILLDKVEDQKLKERIENFKFFGQYADFKSLKSYNHGDVSINSNVPSYDAKFKMSNKDENVKQLRSRYNIPTDKAPILKMHIDGDLKGSSVGYKKLEIDFSKEENSELSIVDSLNFQPAKNKDDE

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]