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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA0837 [new locus tag: SA_RS04750 ]
  • pan locus tag?: SAUPAN003116000
  • symbol: SA0837
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA0837 [new locus tag: SA_RS04750 ]
  • symbol: SA0837
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 950291..951436
  • length: 1146
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGATTCGAATTCAAGATAATACAATAAGGGATGGTATGCAACAAAGTAATGTTCGAAAA
    AGTCTAATTATAAAAAAAGAAGTATTGAAACAAATTAACAAGTTAAATATAAATTCTGTT
    GAAGTAGGCATGTGTACAACTATCGAGGATGAATTTAATATTCATCAATTCAGAGACATT
    TTAAGTCCTGAAAAAGAATTAGTAGTATTGACTAGGCTTAATGAAAAAGAAATAAAAAAA
    ATAGTCAAATTGAAAATTCATAATTTAGTGGTAAAAATACTATTGCCAATATCTGACTTG
    CATATAAAAGAAAAGCTTAATTTTTCAAATAAATATTATATTCAGAAAATCAAAGACTGC
    TTGGATATATTAAAGAAAGATAAAAAAGGAGTAGATATTTGTTTTGAAGATGCAACAAGG
    ACTTCTAGAGAAAAATTGAAAGAATACATGGAAATTATTTCAAAATATCAAGTTAGAACA
    GTTACATTTGCGGACACTGTAGGATGTTCGACACCATTAGAATACGGAGATATTTTTAAT
    TACTTTGTAAAAAAATATTCTAACATAATTTTTTCTGCTCATTGTCATAACGATCTAGGG
    TTGGCTACTGCAAATACATTAGCTGCAATTTTAAATGGTGCAAAGCAAATAGAAACTACA
    TTTTTGGGAATTGGTGAGAGAGCGGGTAATGCTCCTATTGAGGAAATAATTACTATTTTG
    ACAAAAAAACAAATAGAAAGTACGGAATTCACTTTACCCGACGTATATAAAACTAGTATT
    AATATTTCTAAAATTCTCGATTTTCAAATATCAGAAAACAAACCTATAATTGGTGAAAAT
    ATATTTAAACATGAATCAGGAATTCATCAAGATGGTACTAAAAAAAATATAAATATGTAT
    CAATATTTAGTTCCTAGTGATTTAGGATTGAAAAATTCACAAGTTGTTCAGTTTCCAATA
    AGTAATATTTCTAGTAAGAAAATCTTGCACAATAAATTTAAATCAATAGTTAACACTGAA
    GAAATTGATGAAAATATTTCTTTCTATAAACTTGTGAACAAGTTTTCACCTGAAGTAGCA
    CCTGAAGATACAGTGGATTTACTTCAGATAATAAAAAGGAGGAGTAAAGATGGAAATTTT
    AAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1146

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA0837 [new locus tag: SA_RS04750 ]
  • symbol: SA0837
  • description: hypothetical protein
  • length: 381
  • theoretical pI: 9.15783
  • theoretical MW: 43688.3
  • GRAVY: -0.304199

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismAmino acid biosynthesisPyruvate family2-isopropylmalate synthase (TIGR00973; EC 2.3.3.13; HMM-score: 230.2)
    MetabolismBiosynthesis of cofactors, prosthetic groups, and carriersOtherhomocitrate synthase (TIGR02660; EC 2.3.3.14; HMM-score: 225)
    MetabolismCentral intermediary metabolismNitrogen fixationhomocitrate synthase (TIGR02660; EC 2.3.3.14; HMM-score: 225)
    isopropylmalate/citramalate/homocitrate synthases (TIGR02090; HMM-score: 204.4)
    homocitrate synthase (TIGR02146; EC 2.3.3.14; HMM-score: 172.6)
    Unknown functionGeneralcitramalate synthase (TIGR00977; EC 2.3.1.182; HMM-score: 105.8)
    MetabolismEnergy metabolismOther4-hydroxy-2-oxovalerate aldolase (TIGR03217; EC 4.1.3.39; HMM-score: 63.3)
    MetabolismAmino acid biosynthesisPyruvate family2-isopropylmalate synthase (TIGR00970; EC 2.3.3.13; HMM-score: 56.4)
    MetabolismTransport and binding proteinsCations and iron carrying compoundsoxaloacetate decarboxylase alpha subunit (TIGR01108; EC 4.1.1.3; HMM-score: 27.3)
    MetabolismEnergy metabolismOtheroxaloacetate decarboxylase alpha subunit (TIGR01108; EC 4.1.1.3; HMM-score: 27.3)
  • TheSEED:  
    FIG01108309: hypothetical protein 
  • PFAM:
    TIM_barrel (CL0036) HMGL-like; HMGL-like (PF00682; HMM-score: 192.5)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.124
    • Ymax_pos: 38
    • Cmax: 0.105
    • Cmax_pos: 51
    • Smax: 0.206
    • Smax_pos: 30
    • Smean: 0.121
    • D: 0.123
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MIRIQDNTIRDGMQQSNVRKSLIIKKEVLKQINKLNINSVEVGMCTTIEDEFNIHQFRDILSPEKELVVLTRLNEKEIKKIVKLKIHNLVVKILLPISDLHIKEKLNFSNKYYIQKIKDCLDILKKDKKGVDICFEDATRTSREKLKEYMEIISKYQVRTVTFADTVGCSTPLEYGDIFNYFVKKYSNIIFSAHCHNDLGLATANTLAAILNGAKQIETTFLGIGERAGNAPIEEIITILTKKQIESTEFTLPDVYKTSINISKILDFQISENKPIIGENIFKHESGIHQDGTKKNINMYQYLVPSDLGLKNSQVVQFPISNISSKKILHNKFKSIVNTEEIDENISFYKLVNKFSPEVAPEDTVDLLQIIKRRSKDGNFK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]