NCBI: 26-AUG-2013
Contents
⊟Summary[edit source | edit]
- organism: Staphylococcus aureus N315
- locus tag: SA1598 [new locus tag: SA_RS09000 ]
- pan locus tag?: SAUPAN004476000
- symbol: SA1598
- pan gene symbol?: spdA
- synonym:
- product: hypothetical protein
⊟Genome View[edit source | edit]
⊟Gene[edit source | edit]
⊟General[edit source | edit]
- type: CDS
- locus tag: SA1598 [new locus tag: SA_RS09000 ]
- symbol: SA1598
- product: hypothetical protein
- replicon: chromosome
- strand: +
- coordinates: 1835822..1836457
- length: 636
- essential: no DEG other strains
⊟Accession numbers[edit source | edit]
- Gene ID: 1124444 NCBI
- RefSeq: NP_374887 NCBI
- MicrobesOnline: 103913 MicrobesOnline
⊟Phenotype[edit source | edit]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit source | edit]
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601ATGCAAAAATTCAAAGACTTTTTTTACGATGATTTATCGGTTACACGAGGAAATTATTTT
TTAACTTTAATGGCAGCATTTTTTATTACTATCATTTTATTTATCGGCATAGTTGTCAGT
GAAGTACATTTACTTTATAGCATGCTAATTGTATTAGTAGGTTTAATTCTATTGAGGCTA
TTCAAAATCAATTTATTCTCTTTTAAAAAATTAACATTGTCTCAAGTTATTTATATTATA
GGCGGTGCACTATTAATTTATGGGTTAGATAATCTTTATTTATATTTTCATGACGTACCG
GCAAATGAACTACAATTAGAGCAAGAAATACGAAATACACCATTCTATATTTCTATTTTC
ACTGTTACCATCATCCCCGCTATTGTGGAAGAAATTGTTTTTCGCGGTATGATAATAAGG
GTTATATTCAGAAAACACTTATTTTTAGGGTTACTTGTGTCTAGTTTAGTTTTTGCATCA
TTACACGAATCTGACACTTGGATTGGTTATTTACCTTACTTATATTCTGGTTTGATTTTT
GGTCTAATTTATATAAAAACAAAACGATTAGAAGTGGTAATATTCATGCACTTCTTAAAT
AACTTGTTAGCTCTGCTCTTTATAATATGGGGATAA60
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⊟Protein[edit source | edit]
⊟General[edit source | edit]
- locus tag: SA1598 [new locus tag: SA_RS09000 ]
- symbol: SA1598
- description: hypothetical protein
- length: 211
- theoretical pI: 8.67223
- theoretical MW: 24540.4
- GRAVY: 1.00995
⊟Function[edit source | edit]
- reaction:
- TIGRFAM: exosortase E/protease, VPEID-CTERM system (TIGR04162; EC 3.4.22.-; HMM-score: 30.4)Cell envelopeBiosynthesis and degradation of surface polysaccharides and lipopolysaccharidesCAAX prenyl protease-related protein (TIGR03008; HMM-score: 23.7)
- TheSEED:
- PFAM: Peptidase_U (CL0472) Abi; CAAX protease self-immunity (PF02517; HMM-score: 56)
⊟Structure, modifications & interactions[edit source | edit]
- domains:
- modifications:
- cofactors:
- effectors:
- protein partners:
⊟Localization[edit source | edit]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 7
- LocateP: Multi-transmembrane
- Prediction by SwissProt Classification: Membrane
- Pathway Prediction: Sec-(SPI)
- Intracellular Possibility: 0.17
- Signal Peptide Possibility: -0.5
- N-terminally Anchored Score: 1
- Predicted Cleavage Site: No CleavageSite
- SignalP: no predicted signal peptide
- Ymax: 0.095
- Ymax_pos: 70
- Cmax: 0.174
- Cmax_pos: 41
- Smax: 0.123
- Smax_pos: 66
- Smean: 0.045
- D: 0.075
- predicted transmembrane helices (TMHMM): 7
⊟Accession numbers[edit source | edit]
⊟Protein sequence[edit source | edit]
- MQKFKDFFYDDLSVTRGNYFLTLMAAFFITIILFIGIVVSEVHLLYSMLIVLVGLILLRLFKINLFSFKKLTLSQVIYIIGGALLIYGLDNLYLYFHDVPANELQLEQEIRNTPFYISIFTVTIIPAIVEEIVFRGMIIRVIFRKHLFLGLLVSSLVFASLHESDTWIGYLPYLYSGLIFGLIYIKTKRLEVVIFMHFLNNLLALLFIIWG
⊟Experimental data[edit source | edit]
- experimentally validated: no data available
⊟Expression & Regulation[edit source | edit]
⊟Operon[edit source | edit]
- SA1598 no polycistronic organisation predicted
⊟Regulation[edit source | edit]
- sigma factor:
- regulator:
⊟Transcription pattern[edit source | edit]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit source | edit]
- Aureolib: no data available
⊟Protein stability[edit source | edit]
- half-life: no data available
⊟Biological Material[edit source | edit]
⊟Mutants[edit source | edit]
⊟Expression vector[edit source | edit]
⊟lacZ fusion[edit source | edit]
⊟GFP fusion[edit source | edit]
⊟two-hybrid system[edit source | edit]
⊟FLAG-tag construct[edit source | edit]
⊟Antibody[edit source | edit]
⊟Other Information[edit source | edit]
You are kindly invited to share additional interesting facts.
⊟Literature[edit source | edit]
⊟References[edit source | edit]
⊟Relevant publications[edit source | edit]
Matthew B Frankel, Brandon M Wojcik, Andrea C DeDent, Dominique M Missiakas, Olaf Schneewind
ABI domain-containing proteins contribute to surface protein display and cell division in Staphylococcus aureus.
Mol. Microbiol.: 2010, 78(1);238-52
[PubMed:20923422] [WorldCat.org] [DOI] (I p)