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NCBI: 26-AUG-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA2075 [new locus tag: SA_RS11930 ]
  • pan locus tag?: SAUPAN005741000
  • symbol: FdhD
  • pan gene symbol?: fdhD
  • synonym:
  • product: formate dehydrogenase accessory protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA2075 [new locus tag: SA_RS11930 ]
  • symbol: FdhD
  • product: formate dehydrogenase accessory protein
  • replicon: chromosome
  • strand: +
  • coordinates: 2335372..2336169
  • length: 798
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAACAAAGATGTATCTTTAGGTCAACCAATTGTTAGATATGAAGATGGAAAATTATTC
    AATACAACAGATCAATATGTGACAGAATTTCCACTTACAATTATGGTGAATGGTGAAGAA
    TTTGCGACTGTTATATGCAGTCCAACAAACCTTGAGGAGTTAGTCATTGGATTTCTGGCT
    TCGGAAGGTGCCATTTTAAAGCGAGATGAATTAAAATCTGTGCTGATTGATGATAGTAAA
    GGTTTTGCCCATGTTGAACTTAATAAAGATTTAGGCGATCGCTTTCAATATTCCACAAAA
    CGAATGATTGCATCTTGTTGTGGAAAGAGTCGTGAGTTTTATTTTCAAAATGATGCTGCT
    ATCGCTAAAACTTCTATGTCTAAAATCACTTTAACTCCAATACAAATTATTAACATGATG
    ACTCGATTACAAAGTGCAAGTCATATTTACCAAGAAACAGGTGGCTTACATAATGCTGCT
    ATAAGCGATGGTTTGACATTTTTTGTACATCGACAAGACATTGGTAGACATAACGCTCTA
    GATAAATTATATGGATTTTGTATCCAGCGACATATTACTGTCCGAGATAAAGTATTAATT
    TTTAGTGGACGTATTTCATCAGAAATTTTAATTAAAGCCGCGAAAATCGGTGTTGGCGTC
    ATTTTATCTAAATCAGCTCCGACAACGCTTGCTGTAACCTTAGCTAATGACCTAAATATT
    ACGGCAGTAGGTTTTATTCGAAATGGTGGCTTTAATATATATAGTCATCCAGAACGTATC
    ATCGACTCTGAACAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    798

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA2075 [new locus tag: SA_RS11930 ]
  • symbol: FdhD
  • description: formate dehydrogenase accessory protein
  • length: 265
  • theoretical pI: 7.17929
  • theoretical MW: 29397.6
  • GRAVY: -0.0260377

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismEnergy metabolismAnaerobicformate dehydrogenase family accessory protein FdhD (TIGR00129; HMM-score: 240.5)
    MetabolismEnergy metabolismElectron transportformate dehydrogenase family accessory protein FdhD (TIGR00129; HMM-score: 240.5)
  • TheSEED:  
    RespirationRespiration - no subcategoryFormate hydrogenase Formate dehydrogenase chain D (EC 1.2.1.2) 
  • PFAM:
    CDA (CL0109) FdhD-NarQ; FdhD/NarQ family (PF02634; HMM-score: 240.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.099
    • Ymax_pos: 48
    • Cmax: 0.112
    • Cmax_pos: 43
    • Smax: 0.142
    • Smax_pos: 36
    • Smean: 0.074
    • D: 0.09
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MNKDVSLGQPIVRYEDGKLFNTTDQYVTEFPLTIMVNGEEFATVICSPTNLEELVIGFLASEGAILKRDELKSVLIDDSKGFAHVELNKDLGDRFQYSTKRMIASCCGKSREFYFQNDAAIAKTSMSKITLTPIQIINMMTRLQSASHIYQETGGLHNAAISDGLTFFVHRQDIGRHNALDKLYGFCIQRHITVRDKVLIFSGRISSEILIKAAKIGVGVILSKSAPTTLAVTLANDLNITAVGFIRNGGFNIYSHPERIIDSEQ

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • FdhD no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]