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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA2219 [new locus tag: SA_RS12745 ]
  • pan locus tag?: SAUPAN005978000
  • symbol: SA2219
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA2219 [new locus tag: SA_RS12745 ]
  • symbol: SA2219
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2491623..2492009
  • length: 387
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAAACTAACACAAACGCATGCTGAAATTTTAAAATTTATCATTGTTGGCGGCATTAAT
    ACGTTAAATTATTATGTTGTCTATTTATTGCTGTTAAAATTATTACACATTGAATATATG
    ATTAGTCATATTACCGGATTTCTAGTCGCTTTTGTGATTTCGTATTATTTGAATTGTTAT
    TTTGTTTACAGGGTAAAACCTACTTGGAGAAAATTCATTAGTTTTCCAATTACGCAGATT
    GTCAACGTAAGCTTACAAACAGTTTTATTATATGTTTTTGTATCCTGGCTAAATTTGCCA
    GCGGAAATTGCGCCATTTGCAGGTTTAGTGATTACGATACCCATCACATTTGTATTATCT
    AAATGGATTTTAAAAGATAGTAATTAA
    60
    120
    180
    240
    300
    360
    387

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA2219 [new locus tag: SA_RS12745 ]
  • symbol: SA2219
  • description: hypothetical protein
  • length: 128
  • theoretical pI: 9.70953
  • theoretical MW: 14864.8
  • GRAVY: 0.907812

Function[edit | edit source]

  • TIGRFAM:
  • TheSEED  :
    • Putative sugar translocase in surface polysaccharides biosynthesis
  • PFAM:
    no clan defined GtrA; GtrA-like protein (PF04138; HMM-score: 82.4)
    and 2 more
    DUF4229; Protein of unknown function (DUF4229) (PF14012; HMM-score: 8.3)
    MNHE; Na+/H+ ion antiporter subunit (PF01899; HMM-score: 7.8)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular possibility: 0.17
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.000708
    • TAT(Tat/SPI): 0.000085
    • LIPO(Sec/SPII): 0.012672
  • predicted transmembrane helices (TMHMM): 4

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MKLTQTHAEILKFIIVGGINTLNYYVVYLLLLKLLHIEYMISHITGFLVAFVISYYLNCYFVYRVKPTWRKFISFPITQIVNVSLQTVLLYVFVSWLNLPAEIAPFAGLVITIPITFVLSKWILKDSN

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]