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NCBI: 26-AUG-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus N315
  • locus tag: SA2414 [new locus tag: SA_RS13830 ]
  • pan locus tag?: SAUPAN006329000
  • symbol: SA2414
  • pan gene symbol?: gpxA2
  • synonym:
  • product: hypothetical protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SA2414 [new locus tag: SA_RS13830 ]
  • symbol: SA2414
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 2708243..2708740
  • length: 498
  • essential: no DEG other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAATAATAGAAATGTGTATGATATCGAAGTAAGTGATTATAAAGGCTTAACTTATAAA
    TTAGAAGCATTTAGAGGTAAAGTGATTTTAGTTGTTAATACTGCAACAGAATGTATATAT
    AGCGAACAATTGAAAAAACTAGAGACTTTGTTTCAAAAATATAAGGATCGTGGGTTTGTA
    GTGTTGAGTTTTCCGAATAATAATTTTGACAATCGACAACCAGGTTCTAATGAAGAAATC
    TTGAAAATTAGTCGTGAGAAATTTGGTGTTACATTTCCAGTGCTAGCTAAAATATCTGTG
    AACGGGAACGATGAACATCCGTTATTTACGCATTTAAAGAATGAACAACCAGGAATCTTT
    GGGTCCCCAATAAAATGGAATTTCACAAAATTTATAATCGATCGACAAGGCAATGTTGTA
    AATCGATTCTTGCCAATGGAAGATCCATTGGATATATCGACAAATATAGAAATATTATTG
    CAAGAATCTTCATCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    498

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SA2414 [new locus tag: SA_RS13830 ]
  • symbol: SA2414
  • description: hypothetical protein
  • length: 165
  • theoretical pI: 6.53912
  • theoretical MW: 19007.5
  • GRAVY: -0.400606

Function[edit | edit source]

  • TIGRFAM:
    putative glutathione peroxidase Gpx7 (TIGR02540; EC 1.11.1.9; HMM-score: 106.6)
  • TheSEED  :
    • Glutathione peroxidase (EC 1.11.1.9)
    • Thioredoxin peroxidase (EC 1.11.1.24)
    Stress Response Oxidative stress Glutathione: Redox cycle  Glutathione peroxidase (EC 1.11.1.9)
    and 1 more
    Stress Response Oxidative stress Glutathione: Redox cycle  Glutathione peroxidase family protein
  • PFAM:
    Thioredoxin (CL0172) GSHPx; Glutathione peroxidase (PF00255; HMM-score: 111.2)
    and 4 more
    AhpC-TSA; AhpC/TSA family (PF00578; HMM-score: 20.6)
    Redoxin; Redoxin (PF08534; HMM-score: 19.3)
    no clan defined DUF2691; Protein of unknown function (DUF2691) (PF10903; HMM-score: 13.9)
    Thioredoxin (CL0172) SCO1-SenC; SCO1/SenC (PF02630; HMM-score: 12.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00904
    • TAT(Tat/SPI): 0.000446
    • LIPO(Sec/SPII): 0.002575
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MNNRNVYDIEVSDYKGLTYKLEAFRGKVILVVNTATECIYSEQLKKLETLFQKYKDRGFVVLSFPNNNFDNRQPGSNEEILKISREKFGVTFPVLAKISVNGNDEHPLFTHLKNEQPGIFGSPIKWNFTKFIIDRQGNVVNRFLPMEDPLDISTNIEILLQESSS

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]