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NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL0185 [new locus tag: SACOL_RS00945 ]
  • pan locus tag?: SAUPAN001057000
  • symbol: SACOL0185
  • pan gene symbol?:
  • synonym:
  • product: peptide ABC transporter permease

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL0185 [new locus tag: SACOL_RS00945 ]
  • symbol: SACOL0185
  • product: peptide ABC transporter permease
  • replicon: chromosome
  • strand: +
  • coordinates: 216035..217342
  • length: 1308
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    TTGTATCACAAGGCATTTTACAAGTTTGTATTATCGGTATTAAGCTTGCCAATATTTTTA
    TATGCAGTGATAAAGTTTTTCTTTTCTGCTAAGAGGAAAAATTTTTACGCTAATAATTCT
    GAAATTTCAGAAATTGAACAGGCGTTACATCAAAAATATAAATATTTATCGCAGCAAAAG
    TCATCCACACAAATACATAAAGAAGCATTAAAAATATTCAAGGCACAAAGTTCTAATACG
    AGTTCAAAGAATATTGAACAAGCACATTTTTCAACATACTTTGAAAATGTATTATTTCAT
    AAGTTCATCATGATCAAAGTGATATTGGCCTTGCCGATGTTCATCTTATTGACTTTTTAT
    TTACAGCCATTAGTTAGATATATTTTTGAACGAATTGTCATGGCTGTGATTGTCATCATT
    GGTGTTATTGTCAGTGTGTTTACCATTCTGTATTTTTCACCGCTTGATGCGGCTTATAGC
    ATACTGGGACAAAATGCAACAAAGGCACAGATACATCAATTCAATGTATTACATCATCTT
    AACGAACCTTATTTTATTCAATTGTGGGATACCATCAAGGGTGTTTTTACCTTTGACTTA
    GGTACGACTTACAAAGGGAATGAGGTTGTGACTAAAGCAGTTGGCGAAAGAATTCCAATT
    ACAATAATTGTCGCAGTATTAGCGCTAATGGTGGCATTAATTATTGCAATACCAATTGGT
    ATTATCAGTGCGATGAAGCGAAATAGTTGGCTTGATATCACGTTAATGATAATTGCATTA
    ATTGGTTTATCTATTCCAAGTTTCTGGCAAGGGCTATTATTCATTTTAGCGTTCTCATTG
    AAATTGGATATTTTGCCACCATCTTATATGCCAGAACATCCAATATCGTTGATTTTACCT
    GTACTTGTCATTGGAACAAGTATTGCTGCTTCTATCACGCGTATGACAAGGTCTTCTGTA
    CTTGAAGTAATGCGCAGCGATTATGTTTTAACTGCTTATGCAAAAGGATTATCGACGACA
    CAAGTTGTTATTAAACATATTTTGAAAAATGCCATTATTCCAATTGTAACGTTAGTTGGT
    CTTCTAGTGGCAGAGTTACTAGGCGGTTCAGCAGTGACGGAACAAGTATTTAACATTAAT
    GGTATCGGGCGTTATATCGTCCAAAAACAACTAATACCTGATATTCCAGCAGTCATGGGT
    GGGGTCGTATATATATCAATTGTAATATCTTTAGCAAACTTAATTATTGATATATTTTAT
    GCTTTAATCGATCCAAAATTACGTAGTGAAATCAACGAAAGGAAGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1308

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL0185 [new locus tag: SACOL_RS00945 ]
  • symbol: SACOL0185
  • description: peptide ABC transporter permease
  • length: 435
  • theoretical pI: 9.94543
  • theoretical MW: 48878
  • GRAVY: 0.668276

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsCations and iron carrying compoundsnickel ABC transporter, permease subunit NikB (TIGR02789; EC 3.6.3.24; HMM-score: 205.8)
    MetabolismTransport and binding proteinsCations and iron carrying compoundsnickel ABC transporter, permease subunit NikC (TIGR02790; EC 3.6.3.24; HMM-score: 35.8)
  • TheSEED:  
    Sulfur MetabolismOrganic sulfur assimilationUtilization of glutathione as a sulphur source Putative glutathione transporter, permease component 
  • PFAM:
    BPD_transp_1 (CL0404) BPD_transp_1; Binding-protein-dependent transport system inner membrane component (PF00528; HMM-score: 139.4)
    Transporter (CL0375) Fig1; Ca2+ regulator and membrane fusion protein Fig1 (PF12351; HMM-score: 18.5)
    no clan definedOrbi_VP2; Orbivirus outer capsid protein VP2 (PF00898; HMM-score: 10.4)
    DUF3995; Protein of unknown function (DUF3995) (PF13160; HMM-score: 10.3)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 8
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -0.5
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.244
    • Ymax_pos: 23
    • Cmax: 0.187
    • Cmax_pos: 38
    • Smax: 0.679
    • Smax_pos: 1
    • Smean: 0.453
    • D: 0.326
  • predicted transmembrane helices (TMHMM): 8

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MYHKAFYKFVLSVLSLPIFLYAVIKFFFSAKRKNFYANNSEISEIEQALHQKYKYLSQQKSSTQIHKEALKIFKAQSSNTSSKNIEQAHFSTYFENVLFHKFIMIKVILALPMFILLTFYLQPLVRYIFERIVMAVIVIIGVIVSVFTILYFSPLDAAYSILGQNATKAQIHQFNVLHHLNEPYFIQLWDTIKGVFTFDLGTTYKGNEVVTKAVGERIPITIIVAVLALMVALIIAIPIGIISAMKRNSWLDITLMIIALIGLSIPSFWQGLLFILAFSLKLDILPPSYMPEHPISLILPVLVIGTSIAASITRMTRSSVLEVMRSDYVLTAYAKGLSTTQVVIKHILKNAIIPIVTLVGLLVAELLGGSAVTEQVFNINGIGRYIVQKQLIPDIPAVMGGVVYISIVISLANLIIDIFYALIDPKLRSEINERK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]