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NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL0639 [new locus tag: SACOL_RS03300 ]
  • pan locus tag?: SAUPAN002374000
  • symbol: SACOL0639
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL0639 [new locus tag: SACOL_RS03300 ]
  • symbol: SACOL0639
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 671333..671674
  • length: 342
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    ATGAAAAATACATTCCTTATTTGTGATGAATGTCAGGCAGTCAATATAAGAACGTTACAA
    AAGAAGTTGGAAAAATTAGATCCCGATGCTGAAATCGTGATAGGTTGTCAATCTTATTGT
    GGACCTGGACGCCGAAAAACATTCACTTTTGTTAATAACCGCCCACTGGCTGCGCTTACT
    GAAGAAGAATTAATCGAAAAAGTTTCTCAACAATTAAAGAAACCACGTGATCCTGAAGAA
    GAAGAGCGTTTAAGAAAACGACATGAAGAACGTAAACGTCGTAAAGAAGAACAAGATAGA
    AAGCTTAAAGAAAAATTAGAAAAGCGAAAAGCACAACAATAA
    60
    120
    180
    240
    300
    342

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL0639 [new locus tag: SACOL_RS03300 ]
  • symbol: SACOL0639
  • description: hypothetical protein
  • length: 113
  • theoretical pI: 9.89847
  • theoretical MW: 13535.5
  • GRAVY: -1.31239

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingProtein synthesistRNA aminoacylationglutamyl-tRNA(Gln) amidotransferase, subunit D (TIGR02153; EC 6.3.5.-; HMM-score: 8.9)
  • TheSEED:  
    FIG01308914: hypothetical protein YwzC 
  • PFAM:
    no clan definedDUF1450; Protein of unknown function (DUF1450) (PF07293; HMM-score: 31.7)
    Zn_Beta_Ribbon (CL0167) DUF2072; Zn-ribbon containing protein (PF09845; HMM-score: 15.7)
    BCLiA (CL0551) APG6; Autophagy protein Apg6 (PF04111; HMM-score: 8.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 0.83
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.136
    • Ymax_pos: 23
    • Cmax: 0.107
    • Cmax_pos: 27
    • Smax: 0.221
    • Smax_pos: 21
    • Smean: 0.158
    • D: 0.145
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MKNTFLICDECQAVNIRTLQKKLEKLDPDAEIVIGCQSYCGPGRRKTFTFVNNRPLAALTEEELIEKVSQQLKKPRDPEEEERLRKRHEERKRRKEEQDRKLKEKLEKRKAQQ

Experimental data[edit source | edit]

  • experimental localization: Cytoplasmic [1]

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int. J. Med. Microbiol.: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

Relevant publications[edit source | edit]