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NCBI: 10-JUN-2013

⊟Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1017 [new locus tag: SACOL_RS05190 ]
  • pan locus tag?: SAUPAN003186000
  • symbol: SACOL1017
  • pan gene symbol?: —
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit source | edit]

⊟Gene[edit source | edit]

⊟General[edit source | edit]

  • type: CDS
  • locus tag: SACOL1017 [new locus tag: SACOL_RS05190 ]
  • symbol: SACOL1017
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1024606..1025691
  • length: 1086
  • essential: unknown other strains

⊟Accession numbers[edit source | edit]

⊟Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

⊟DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGTTAAACAAGGTTTGGTTCCGAACTGGCATCGCTCTGATTATGCTGTTCATTCTCATC
    AAACTATTTATGGAAGTGCACGAAGTATTTACTCCAATAGCTACAATCATCGGTTCTGTA
    TTTCTTCCATTTTTAATTAGTGGTTTTTTATTTTATATCTGTCTACCTTTTCAAAACTTA
    CTTGAAAAAGTCGGTTTTCCAAGATGGGCTAGTATAACAACAATCATGTTAGCTTTGTTT
    GCTATTATCGGCTTAATTGTTGCGTTTGTTGCACCAATCATCATTTCAAATATCAACAAT
    TTAATTAGTCAGACACCTGCCCTACAAAAAGAAGCAGAGCAAATTATTAAATTCGCACTA
    GCTCAAATGGATAAATTACCTGAAGATGTAACAAGTAGAATTACAAATATGGTTAAATCA
    ATGGGTGATGGCGTTACTAATATTTTATCTAATTCATTACAGTACATTACATCATTAATT
    TCAACCATCTTCTTATTGATTATGGTTCCATTCTTCTTAATTTATATGTTAAAAGACCAT
    GAAAAATTTATCCCAGCTGTTGCTAAATTTTTCAAAGGTGAACGTAAAGTATTTTTCGTA
    GATTTATTAACTGATTTAAACTTTACATTAAAATCTTACATTCAAGGTCAAGTAACTGTC
    AGTGTTATTTTAGGTATATTCTTATATATCGGTTATTCAATTATTGACTTACCATATATT
    CCTTTATTAGTACTATTTGCTGGTGTCGCAAACTTAATTCCTTTCTTAGGTTCATGGTTA
    TCATTTGCACCTGCAGCAATACTCGGTATTATAGATAGTCCTACTACATTTATATGGGTT
    TGTATCATTACATTAATTGCACATCAACTTGAAGGTAATATCATTACACCAAATGTAATG
    GGTAAATCTTTAAGTATCCATCCTTTAACAATTATCGTTGTTATTTTAGCAGCAGGAGAT
    TTAGGTGGCTTTACATTAGTTCTGATTGCAGTGCCATTATATGCTGTACTTAAAACGGTT
    GTTAGTAATATTTTCAAATACCGCCAACGCATTATTGATAAAGCAAACAGTAATGTTAAG
    GACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1086

⊟Protein[edit source | edit]

⊟General[edit source | edit]

  • locus tag: SACOL1017 [new locus tag: SACOL_RS05190 ]
  • symbol: SACOL1017
  • description: hypothetical protein
  • length: 361
  • theoretical pI: 9.22205
  • theoretical MW: 40154.1
  • GRAVY: 0.97036

⊟Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Cellular processesCellular processesSporulation and germinationsporulation integral membrane protein YtvI (TIGR02872; HMM-score: 76.9)
    P-type conjugative transfer protein TrbJ (TIGR02780; HMM-score: 11.1)
  • TheSEED:  
    UPF0118 membrane protein SAV1012 
  • PFAM:
    no clan definedAI-2E_transport; AI-2E family transporter (PF01594; HMM-score: 211.2)
    ECSCR; Endothelial cell-specific chemotaxis regulator (PF15820; HMM-score: 6.2)

⊟Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

⊟Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 8
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.135
    • Ymax_pos: 11
    • Cmax: 0.111
    • Cmax_pos: 25
    • Smax: 0.234
    • Smax_pos: 2
    • Smean: 0.17
    • D: 0.149
  • predicted transmembrane helices (TMHMM): 9

⊟Accession numbers[edit source | edit]

⊟Protein sequence[edit source | edit]

  • MLNKVWFRTGIALIMLFILIKLFMEVHEVFTPIATIIGSVFLPFLISGFLFYICLPFQNLLEKVGFPRWASITTIMLALFAIIGLIVAFVAPIIISNINNLISQTPALQKEAEQIIKFALAQMDKLPEDVTSRITNMVKSMGDGVTNILSNSLQYITSLISTIFLLIMVPFFLIYMLKDHEKFIPAVAKFFKGERKVFFVDLLTDLNFTLKSYIQGQVTVSVILGIFLYIGYSIIDLPYIPLLVLFAGVANLIPFLGSWLSFAPAAILGIIDSPTTFIWVCIITLIAHQLEGNIITPNVMGKSLSIHPLTIIVVILAAGDLGGFTLVLIAVPLYAVLKTVVSNIFKYRQRIIDKANSNVKD

⊟Experimental data[edit source | edit]

  • experimentally validated: PeptideAtlas
    experimental localization: Integral membrane [1] [2]

⊟Expression & Regulation[edit source | edit]

⊟Operon[edit source | edit]

  • SACOL1017 no polycistronic organisation predicted

⊟Regulation[edit source | edit]

  • sigma factor:
  • regulator:

⊟Transcription pattern[edit source | edit]

⊟Protein synthesis (provided by Aureolib)[edit source | edit]

⊟Protein stability[edit source | edit]

  • half-life: no data available

⊟Biological Material[edit source | edit]

⊟Mutants[edit source | edit]

⊟Expression vector[edit source | edit]

⊟lacZ fusion[edit source | edit]

⊟GFP fusion[edit source | edit]

⊟two-hybrid system[edit source | edit]

⊟FLAG-tag construct[edit source | edit]

⊟Antibody[edit source | edit]

⊟Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

⊟Literature[edit source | edit]

⊟References[edit source | edit]

  1. ↑ Dörte Becher, Kristina Hempel, Susanne Sievers, Daniela Zühlke, Jan Pané-Farré, Andreas Otto, Stephan Fuchs, Dirk Albrecht, Jörg Bernhardt, Susanne Engelmann, Uwe Völker, Jan Maarten van Dijl, Michael Hecker
    A proteomic view of an important human pathogen--towards the quantification of the entire Staphylococcus aureus proteome.
    PLoS ONE: 2009, 4(12);e8176
    [PubMed:19997597] [WorldCat.org] [DOI] (I e)
  2. ↑ Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int. J. Med. Microbiol.: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit source | edit]

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