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NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1038 [new locus tag: SACOL_RS05300 ]
  • pan locus tag?: SAUPAN003223000
  • symbol: SACOL1038
  • pan gene symbol?:
  • synonym:
  • product: membrane protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL1038 [new locus tag: SACOL_RS05300 ]
  • symbol: SACOL1038
  • product: membrane protein
  • replicon: chromosome
  • strand: +
  • coordinates: 1046941..1048905
  • length: 1965
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    ATGAAATGGTTCAAATTAATACTTGATGTTACAATCTTCATTCTGATTGCTATATTGTTA
    TTTGTTTATACATATAAAGAAAACGAAGAAATATTGCCTGATACTAAATACCCTATAGCG
    GTAACTGACTGGAATAAAAAATATAGTAAAAATGAGATTTATAAACGTATAGATCAATTC
    GCTAAAAATGAGAACGTAGCAATCTATAAATCAACTTCAAATTATACAAACAAAAACGTA
    GATAAAGATATATATGTATTTAATAAATCAAAAGCAGCAACTATCACTCCTTTTAATGCT
    AAATATAACATTCATTATTTAAGTGACGACGAAGTATTAAAAAAAGATATCAAAGGGAGT
    TATTTTGTAAAAGACAAAAATTTTGACGTGTCTAAATTCATAAATTTTTTAAAAGAATAT
    GGTGTTACTGCTGAATCATACAAAATAGATCATATGATGATTGCCGTTGGTGTCATTAAA
    CAAATGAATATAGTAGTTCCATTATCCTCACTTTTAATCGTTTATTTTATTTATTATATT
    TTCGAAAAGAACATTAATTTCAAAGCGTATGCGATTAAGTATTTAAATGGTTTTACATTA
    AGAAAAATAATTTTCGAAAATTTTTCAAAGAAATGCACGTATTGGGTAACGTTAATCATA
    ACTCAAATTCTTTTAACTACAAGTGTACTTTGGATATTAAATTACACGGGTAATTTAGAT
    TTATTCATATTAAGAATAGTTCTGCTTTCATGTCTTTTCATTTTAACGATTAGTGTTATT
    AATTTATGGACTTTCTTAATGTTACTAAATTTAAATATTGCAAATATGATTAAAGGTAAG
    CAGCACTTTAAAACAATTCGTTTTATTAATACAGTTTGTAAAAGTATTCTCTTAGTACTA
    ATAGCTAATGTAATGATAGAAAATACTAGTGTTATTAAAGATTTGAATAAAATAAAAGAA
    ACTGAGAAATATTGGAATGTATTAGATGATTATTACACGATTGAATTTGCACCTTATCAC
    GAAACAAAACAAAGTTTGATTGATAATATGGTGCGATCAGAACAATTAGTAAAGGCTAGT
    GAAGCAGAAAATAATGCGATTTTATTCAAACCAAAGGGTGACTCCGTTGACAATGACAAC
    TTTTCGCCTGATGAGGGGAATGTAATATTAGTAAATAATCAGTTCTGGTCGATTTATTAC
    AAGCAGTTTCAACCTGATATTCCGATAAAAAATCAAAAAAATAATGTCGAAGTAATTATT
    CCACAAAAGTTTCATGCAATGCGTAATGAAATCAATCAAGCATATCATTCATGGTTTGAA
    TTTGTACAAAATAAAAATAATAAAGAGAATAAGTTATCTATACAGTTTATCAACAAAAAT
    GATTGTCGAATTTTTTCATTTGATGCACGAGATAGTCGCCATTTGTCATTTATAGAGGCG
    CCAATCATTGTGAATGTTCAGGCATCAGATTTATCGAATGATTTTTATTATGCCATGATC
    AGTCAAGGCGGGTATTTATTCAAAAATTATGACGCGCTAGTAAAAAATATTGAAAAGTAT
    CATCTTGATGGGGAAATCAGTGGAATAACCAATTATAAAGATAGCGTGATGGAAATGTAT
    CATGAAAACAATTTGAAATTAACAGTACTCAACTTTTCACAAATCATTATCGCAATCATT
    TTAATAATTATTATTTTATTTGATGTGAAATATTATTTTGAACAGCATCGAAAATTACTC
    GTAATCAAAAAGCTATATGGTTATTCAACATTAAGAGCCAATTACCAATACTTATTAATA
    AATAATATAGTTGTTATTTTTATTGGAATATTGACGAATGTAATTTTACATTCTCACTAT
    ATAATGATGTTATTTGCAACGATTCTTGTCGTTCAAATATTATTGCAGATTTGCAGCCTA
    TACTATCATGGCCGACGTTTTAATGAAGTTATCAAGGAGTTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1965

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL1038 [new locus tag: SACOL_RS05300 ]
  • symbol: SACOL1038
  • description: membrane protein
  • length: 654
  • theoretical pI: 9.18491
  • theoretical MW: 77014.4
  • GRAVY: 0.0704893

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Cellular processesCellular processesToxin production and resistancebacteriocin-associated integral membrane protein (TIGR01654; HMM-score: 751.8)
  • TheSEED:  
    membrane spanning protein 
  • PFAM:
    BPD_transp_1 (CL0404) DUF1430; Protein of unknown function (DUF1430) (PF07242; HMM-score: 47.6)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.154
    • Ymax_pos: 11
    • Cmax: 0.143
    • Cmax_pos: 28
    • Smax: 0.3
    • Smax_pos: 4
    • Smean: 0.233
    • D: 0.185
  • predicted transmembrane helices (TMHMM): 7

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MKWFKLILDVTIFILIAILLFVYTYKENEEILPDTKYPIAVTDWNKKYSKNEIYKRIDQFAKNENVAIYKSTSNYTNKNVDKDIYVFNKSKAATITPFNAKYNIHYLSDDEVLKKDIKGSYFVKDKNFDVSKFINFLKEYGVTAESYKIDHMMIAVGVIKQMNIVVPLSSLLIVYFIYYIFEKNINFKAYAIKYLNGFTLRKIIFENFSKKCTYWVTLIITQILLTTSVLWILNYTGNLDLFILRIVLLSCLFILTISVINLWTFLMLLNLNIANMIKGKQHFKTIRFINTVCKSILLVLIANVMIENTSVIKDLNKIKETEKYWNVLDDYYTIEFAPYHETKQSLIDNMVRSEQLVKASEAENNAILFKPKGDSVDNDNFSPDEGNVILVNNQFWSIYYKQFQPDIPIKNQKNNVEVIIPQKFHAMRNEINQAYHSWFEFVQNKNNKENKLSIQFINKNDCRIFSFDARDSRHLSFIEAPIIVNVQASDLSNDFYYAMISQGGYLFKNYDALVKNIEKYHLDGEISGITNYKDSVMEMYHENNLKLTVLNFSQIIIAIILIIIILFDVKYYFEQHRKLLVIKKLYGYSTLRANYQYLLINNIVVIFIGILTNVILHSHYIMMLFATILVVQILLQICSLYYHGRRFNEVIKEF

Experimental data[edit source | edit]

  • experimental localization: Integral membrane [1]

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int. J. Med. Microbiol.: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

Relevant publications[edit source | edit]