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NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL1557 [new locus tag: SACOL_RS07935 ]
  • pan locus tag?: SAUPAN004067000
  • symbol: SACOL1557
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL1557 [new locus tag: SACOL_RS07935 ]
  • symbol: SACOL1557
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1593474..1594454
  • length: 981
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGTTAAAGTTAAATCCTTACAAGATTGGATTTAGAACAATAAAAACAGCAGTGGGTATG
    ACTTTAGGTGTAATTATTAGTAAGCTGTTAGGTTTAGATAATTATGCTTCAAGCGCCATA
    TTAGTCGTATTATGTATTAAACATACAAAAGTACATTCGCTACAAGCGATTATTTCAAGA
    TTAGTATCATGTTTTTTAGTATTGTTTTTAGGTTCAGCAATATTTAGTTTATTAGGTCAG
    AGTCCAATTGTACTCGGTATTATCGTATTGTTATTTATACCATTAACTGTCGTATTAAAA
    GTACAAGAAGGTGTCATTACGAGTTGCGTTATATTACTTCATGTTTTTAATGCAAAATCA
    ATTGATGCACATTTAATTGTTAATGAAACATTATTACTGTTAATTGGACTAAGCATTGCA
    TTTACAATGAATTTAATGATGCCAAGTTTAGACAAACAACTAGACGAATACAAATGTAAA
    ATTGAGCAACAAATTGCTGATATTTTTAGTAAATATAGTTATATTTGTGAAAAATATGAA
    GATACCATTGCGATTGAATTTGAAGTGTTACTTTTAAATATTAAAAAGGCGAAGTCTATC
    GCGTTCCGAGATGTTAAAAATCATTTTGTTAGAAACGAAAATTCATACTATCATTATTTT
    GATATGCGAGAAGAGCAAGTGGAATTGTTAATGAGAATGAAACCGCTCATCGAAAGTATC
    TGTCATAAAGATCCGCTTTTAAATGATGTTGCGTCACTGCTGAAAGAAATTGGTCTAAAT
    GTGAATAGTAATGACTATACAGCAATGCGTTTACACAATTTGTATGAGACGCGTTTGAAA
    TTGGATGAACTGCCATTGCCAACAACACACAAAGCGCTTAACTCGAGAGCAAGTATTATT
    CAAATATTAAATGAATTAGAAGAATATTTACAAATCAAATCGCAATTTGGTTCATTGAAA
    ATGCATAGTGAAGTAGCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    981

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL1557 [new locus tag: SACOL_RS07935 ]
  • symbol: SACOL1557
  • description: hypothetical protein
  • length: 326
  • theoretical pI: 7.87526
  • theoretical MW: 36972.7
  • GRAVY: 0.371166

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:  
    FIG01108142: hypothetical protein 
  • PFAM:
    FUSC (CL0307) ArAE_1; Aromatic acid exporter family member 1 (PF06081; HMM-score: 146)
    no clan definedArAE_1_C; Putative aromatic acid exporter C-terminal domain (PF11728; HMM-score: 144.1)
    FUSC (CL0307) FUSC_2; Fusaric acid resistance protein-like (PF13515; HMM-score: 18.2)
    DUF2955; Protein of unknown function (DUF2955) (PF11168; HMM-score: 17.6)
    Ig (CL0011) K1; K1 glycoprotein (PF02960; HMM-score: 14.5)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.195
    • Ymax_pos: 13
    • Cmax: 0.147
    • Cmax_pos: 39
    • Smax: 0.452
    • Smax_pos: 6
    • Smean: 0.375
    • D: 0.265
  • predicted transmembrane helices (TMHMM): 4

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MLKLNPYKIGFRTIKTAVGMTLGVIISKLLGLDNYASSAILVVLCIKHTKVHSLQAIISRLVSCFLVLFLGSAIFSLLGQSPIVLGIIVLLFIPLTVVLKVQEGVITSCVILLHVFNAKSIDAHLIVNETLLLLIGLSIAFTMNLMMPSLDKQLDEYKCKIEQQIADIFSKYSYICEKYEDTIAIEFEVLLLNIKKAKSIAFRDVKNHFVRNENSYYHYFDMREEQVELLMRMKPLIESICHKDPLLNDVASLLKEIGLNVNSNDYTAMRLHNLYETRLKLDELPLPTTHKALNSRASIIQILNELEEYLQIKSQFGSLKMHSEVA

Experimental data[edit source | edit]

  • experimentally validated: PeptideAtlas
    experimental localization: Integral membrane [1]

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Andreas Otto, Jan Maarten van Dijl, Michael Hecker, Dörte Becher
    The Staphylococcus aureus proteome.
    Int. J. Med. Microbiol.: 2014, 304(2);110-20
    [PubMed:24439828] [WorldCat.org] [DOI] (I p)

Relevant publications[edit source | edit]