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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2009 [new locus tag: SACOL_RS10490 ]
  • pan locus tag?: SAUPAN005197000
  • symbol: SACOL2009
  • pan gene symbol?:
  • synonym:
  • product: tetracenomycin polyketide synthesis O-methyltransferase TcmP

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL2009 [new locus tag: SACOL_RS10490 ]
  • symbol: SACOL2009
  • product: tetracenomycin polyketide synthesis O-methyltransferase TcmP
  • replicon: chromosome
  • strand: -
  • coordinates: 2069080..2069925
  • length: 846
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAAGCAACTGGTTGGAATTCCCGAATCAATGTTAATTCCTTTGATAGCTCGAGCAAAA
    GAGTACGAAAACGAAAAACCAATAATAAAAGACGCACTATCAAAAAAAATATTTGATGGT
    TTAGATGATATGTACAAAAATGTTACATGTGATGACATGTCTCAAATTGGAATTAGTATA
    CGTACTGTGATAATAGATTGTGTTACTAAGAGGCTTATCAAGGATAATAAAGATTTAATC
    GTGGTCAATATAGGTTGTGGCTTAGATACAAGGTTTCAAAGATTTAATAAAGAAAAAATA
    TCATGGATAGATTTAGATGTACCAGAATCAATAGAAATACGAAAAACATTTTTTAAAGAA
    AGTAATAGTTATAAGATGATATCTAAATCTATGCTAGATTACAGTTGGATTGATGATGTC
    AAAAATTATAAATTTTTTAATAGTAAGTCAGATATATTGTTTATTATTGAAGGTGTATTG
    ATGTATTTTGATGAGAGTGTAATGACTCAATTATTGGACACTATTATCAAAAAGATGGGA
    GATCATAATTTGACATTTGCGATTGAATTTTGCTCAAAAACAATTGCGAATAATACAAAG
    AGACATCAATCGGTATCAAAGTTATCCTCACAACCTGTTTTTAAATATGGTTACAATGAT
    TTAAAAAAATTGAATGAAATTTTACCAAATACAATAAGAGTAATACATGAATATAATTAT
    TTTGACTATTATAAGAATCGATGGGGCTTATTTGGATATTGTAGATTTATACCTTATTTA
    AAAAAAAGGTTAAACAATAAAATAGTACTTATGAAATATAAAGTTCCAAAGAGACAGAGA
    CATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    846

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL2009 [new locus tag: SACOL_RS10490 ]
  • symbol: SACOL2009
  • description: tetracenomycin polyketide synthesis O-methyltransferase TcmP
  • length: 281
  • theoretical pI: 9.74266
  • theoretical MW: 33222.7
  • GRAVY: -0.339502

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Unknown functionEnzymes of unknown specificitymethyltransferase, TIGR00027 family (TIGR00027; EC 2.1.1.-; HMM-score: 41.6)
  • TheSEED:  
    FIG01107971: hypothetical protein 
  • PFAM:
    NADP_Rossmann (CL0063) LCM; Leucine carboxyl methyltransferase (PF04072; HMM-score: 53.8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.163
    • Ymax_pos: 20
    • Cmax: 0.159
    • Cmax_pos: 20
    • Smax: 0.312
    • Smax_pos: 17
    • Smean: 0.169
    • D: 0.165
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MKQLVGIPESMLIPLIARAKEYENEKPIIKDALSKKIFDGLDDMYKNVTCDDMSQIGISIRTVIIDCVTKRLIKDNKDLIVVNIGCGLDTRFQRFNKEKISWIDLDVPESIEIRKTFFKESNSYKMISKSMLDYSWIDDVKNYKFFNSKSDILFIIEGVLMYFDESVMTQLLDTIIKKMGDHNLTFAIEFCSKTIANNTKRHQSVSKLSSQPVFKYGYNDLKKLNEILPNTIRVIHEYNYFDYYKNRWGLFGYCRFIPYLKKRLNNKIVLMKYKVPKRQRH

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]