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NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2357 [new locus tag: SACOL_RS12380 ]
  • pan locus tag?: SAUPAN005869000
  • symbol: SACOL2357
  • pan gene symbol?: htrB
  • synonym:
  • product: ABC transporter permease

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL2357 [new locus tag: SACOL_RS12380 ]
  • symbol: SACOL2357
  • product: ABC transporter permease
  • replicon: chromosome
  • strand: -
  • coordinates: 2416132..2417187
  • length: 1056
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAAATTAGCGATAAAAGAGATTATGTTTTACAAATTTCGTTATATTTTAATCACATTA
    ATCATTCTTTTATTAAGTATTATGGTGTTATTTATTAGTGGTTTAGCTCAAGGGCTTGGT
    AGGGAGAATATTTCGTTATTTGAACACTTTGATAATGATGAATATGTTGTTCAAAAAATG
    AAAGAGCCGCAAATTGAGAAATCGCAACTTAGTGATACGCAACAGAATCAAATTAAAAAG
    GTAATTCATCAAGAACCATATAAAATGAATATTCAAACATTGAAATTATCTAATAAAGAA
    CAAGATGTGATTACAATGAATGACGTTAAACAACAACGCATACAACTTAAAAAAGGTGAT
    TATCCTAAAAATGCTCATGAGGTCGCTATTAATGATAAGTTAGCTGCAGACAACATTAGA
    GTCGGGGATAGATTACATTTTAAAAATAATTCAACTAGTTATAGAGTTTCTGGTATTTTA
    AACGACACAATGTATGCGCATAGTTCCATTGTGCTATTGAACGATAACGGATTTAATGCA
    TTGAATAAGGTTAATACGGCATTTTATCCAGTGAAAAATTTAACACAACAACAACGTGAT
    GAGCTTAATAAAATAAATGACGTTCAAGTTGTGAGTGAAAAAGATTTAACAGGTAATATT
    GCGAGTTATCAAGCAGAGCAAGCACCGTTAAATATGATGATTGTTAGTTTGTTTGCTATT
    ACAGCAATCGTTCTAAGTGCATTTTTCTATGTTATGACGATTCAAAAAATATCACAAATT
    GGCATTTTGAAAGCAATTGGTATTAAGACAAGACATTTATTGAGTGCGTTAGTTTTACAA
    ATTTTAACACTAACAATAATTGGGGTAGGTATTGCTGTGATCATCATAGTAGGACTATCA
    TTTATGATGCCGGTAACGATGCCTTTTTACTTAACAACGCAAAATATTTTATTAATGGTG
    GGGATATTTATATTAGTAGCGATTTTAGGTGCCTCACTATCATTTATCAAATTATTTAAA
    GTGGATCCTATCGAAGCAATTGGAGGTGCAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1056

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL2357 [new locus tag: SACOL_RS12380 ]
  • symbol: SACOL2357
  • description: ABC transporter permease
  • length: 351
  • theoretical pI: 9.58764
  • theoretical MW: 39481.3
  • GRAVY: 0.265242

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    acidobacterial duplicated orphan permease (TIGR03434; HMM-score: 32.9)
    MetabolismTransport and binding proteinsOtherABC exporter transmembrane subunit, DevC protein (TIGR01185; HMM-score: 17.2)
  • TheSEED:  
    Iron acquisition and metabolismIron acquisition and metabolism - no subcategoryHeme, hemin uptake and utilization systems in GramPositives Heme efflux system permease HrtB 
  • PFAM:
    no clan definedMacB_PCD; MacB-like periplasmic core domain (PF12704; HMM-score: 33.2)
    BPD_transp_1 (CL0404) FtsX; FtsX-like permease family (PF02687; HMM-score: 26.8)
    no clan definedDUF1195; Protein of unknown function (DUF1195) (PF06708; HMM-score: 11.4)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0
    • Signal Peptide Possibility: 0.5
    • N-terminally Anchored Score: -1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.172
    • Ymax_pos: 39
    • Cmax: 0.16
    • Cmax_pos: 39
    • Smax: 0.417
    • Smax_pos: 38
    • Smean: 0.127
    • D: 0.155
  • predicted transmembrane helices (TMHMM): 4

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MKLAIKEIMFYKFRYILITLIILLLSIMVLFISGLAQGLGRENISLFEHFDNDEYVVQKMKEPQIEKSQLSDTQQNQIKKVIHQEPYKMNIQTLKLSNKEQDVITMNDVKQQRIQLKKGDYPKNAHEVAINDKLAADNIRVGDRLHFKNNSTSYRVSGILNDTMYAHSSIVLLNDNGFNALNKVNTAFYPVKNLTQQQRDELNKINDVQVVSEKDLTGNIASYQAEQAPLNMMIVSLFAITAIVLSAFFYVMTIQKISQIGILKAIGIKTRHLLSALVLQILTLTIIGVGIAVIIIVGLSFMMPVTMPFYLTTQNILLMVGIFILVAILGASLSFIKLFKVDPIEAIGGAE

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]