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NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL2506 [new locus tag: SACOL_RS13135 ]
  • pan locus tag?: SAUPAN006109000
  • symbol: sarT
  • pan gene symbol?: sarT
  • synonym:
  • product: accessory regulator T

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL2506 [new locus tag: SACOL_RS13135 ]
  • symbol: sarT
  • product: accessory regulator T
  • replicon: chromosome
  • strand: -
  • coordinates: 2563256..2563612
  • length: 357
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    ATGAATGATTTGAAAAGCAAGAGCAATATTAAATTAATGAAAAGAGTATTAACTACATAT
    GAGCTGCGTAAATATTTAAAAAAATATTTTTGTCTTACATTAGATAATTATTTAGTATTA
    GCATATTTAGATGTATTTAAAAATGATGAAGGTAAATATTTTATGAGAGACATTATAAGT
    TATATCGGTATAGACCAATCTAGAATTGTTAAAAGCGTAAAAGATTTATCAAAAAAGGGT
    TACTTGAATAAATGTAGAGACCCACATGATAGTAGAAATGTAATCATTGTTGTTTCTGTA
    AAACAACACAATTATATTAAAAATCTTTTGAGTGAAATAAATATTAATGAAACATAA
    60
    120
    180
    240
    300
    357

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL2506 [new locus tag: SACOL_RS13135 ]
  • symbol: SarT
  • description: accessory regulator T
  • length: 118
  • theoretical pI: 9.99051
  • theoretical MW: 13988.3
  • GRAVY: -0.39322

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Signal transductionRegulatory functionsDNA interactionsstaphylococcal accessory regulator family (TIGR01889; HMM-score: 116.5)
  • TheSEED:  
    Transcriptional regulator SarT (Staphylococcal accessory regulator T) 
  • PFAM:
    HTH (CL0123) HTH_27; Winged helix DNA-binding domain (PF13463; HMM-score: 28.2)
    MarR_2; MarR family (PF12802; HMM-score: 26.5)
    MarR; MarR family (PF01047; HMM-score: 19.5)
    TrmB; Sugar-specific transcriptional regulator TrmB (PF01978; HMM-score: 18.6)
    HTH_36; Helix-turn-helix domain (PF13730; HMM-score: 13.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular Possibility: 1
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.189
    • Ymax_pos: 11
    • Cmax: 0.105
    • Cmax_pos: 53
    • Smax: 0.524
    • Smax_pos: 3
    • Smean: 0.323
    • D: 0.241
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MNDLKSKSNIKLMKRVLTTYELRKYLKKYFCLTLDNYLVLAYLDVFKNDEGKYFMRDIISYIGIDQSRIVKSVKDLSKKGYLNKCRDPHDSRNVIIVVSVKQHNYIKNLLSEININET

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]