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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS00250 [old locus tag: SACOL0047 ]
  • pan locus tag?: SAUPAN000110000
  • symbol: SACOL_RS00250
  • pan gene symbol?:
  • synonym:
  • product: dihydroneopterin aldolase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS00250 [old locus tag: SACOL0047 ]
  • symbol: SACOL_RS00250
  • product: dihydroneopterin aldolase
  • replicon: chromosome
  • strand: -
  • coordinates: 54775..55842
  • length: 1068
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (54775..55842) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
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    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGTCACAATATAAAACGAAACACATTAATGATTTCACTAAAAAAGAATTACAAGAATTG
    AGTTCTAAGGGTCAATTAATTGACGTTCGACATCCTGAAGAATTTGAATTAGGACACATT
    AAAAACGCTTTATTACATTCAGTTGAAAATATAGAGACTTTTAAACAAAGCAAAAATAAA
    ACTTACTATATCTATTGTAAAAGTGGTAATAGAAGTAGAAAAGCCAGTCAATTTCTTGCA
    CAACGCGGATACGATGTAGTGAATTTAGACGGAGGTTATACCGCATACGAACAACAACAT
    CATAATGATAATTTATCTAAAGTAAAAGAAGATAGAGAAATTAAAGATAATCGTAAGACA
    TTCAATTATAGTAATCTACAGTGTCCAGGACCTATTGTTAATATTAGTAAAGAAATCAAA
    AACATCGCTATTGGCGATCAAATAGAAGTTGTTGTGACTGATCACGGATTTTTAAATGAT
    ATTAAAAGTTGGGTCAAACAAACTGGACATACGCTTGTTAGACTCAACGATTTTGGCAAT
    GAAATTCGCGCTATTATTCAAAAAGAAGAAAATAAAAATATAGAAGTGACACACACGAAA
    AGTGGAACAACAATTGTTTTATTTAGCGGCGAGCTAGATAAAGCAGTTGCAGCAATGATT
    ATTGCTAATGGTGCTAAAGCTGCAGGTAGAGATGTAACCATTTTTTGCACATTTTGGGGC
    TTAAATGCACTTAAAAAAATTCAAAGTCAACGTATTAAGAAAAAAGGTATTGCAAAACTT
    TTTGACTTCATGCTTCCAAATTCACCAATTAACATGCCTATTTCTAAAATGAATATGTTT
    GGTTTAGGCAATCTAATGATGCGTTATGTCATGAAAAAGAAAAATGTCGATACTTTACCT
    TCTCTTATTGATCAAGCAGTTGAGCAAGGTGTTAAACTTATCGCTTGTACAATGAGTATG
    GATGTGATGGGCATTACAAAAGAAGAACTACGTGATGATGTAGAATACGGTGGCGTAGGT
    GCATATATTGGATATACAGAACAAGCTAATCACAATTTATTTATATAA
    60
    120
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    960
    1020
    1068

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS00250 [old locus tag: SACOL0047 ]
  • symbol: SACOL_RS00250
  • description: dihydroneopterin aldolase
  • length: 355
  • theoretical pI: 9.29673
  • theoretical MW: 40204.9
  • GRAVY: -0.434085

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingProtein synthesistRNA and rRNA base modificationtRNA 2-selenouridine synthase (TIGR03167; EC 2.9.1.-; HMM-score: 37.6)
    phage shock operon rhodanese PspE (TIGR02981; EC 2.8.1.1; HMM-score: 34.2)
    selenium metabolism protein YedF (TIGR03527; HMM-score: 27.2)
    thiazole biosynthesis domain (TIGR04271; HMM-score: 22.6)
  • TheSEED:
  • PFAM:
    DsrEFH-like (CL0394) DrsE_2; DsrE/DsrF/DrsH-like family (PF13686; HMM-score: 184.7)
    TusA-like (CL0397) TusA; Sulfurtransferase TusA (PF01206; HMM-score: 62.8)
    Phosphatase (CL0031) Rhodanese; Rhodanese-like domain (PF00581; HMM-score: 57.8)
    DsrEFH-like (CL0394) DrsE; DsrE/DsrF-like family (PF02635; HMM-score: 40)
    no clan definedUPF0180; Uncharacterised protein family (UPF0180) (PF03698; HMM-score: 24.4)
    DUF413; Protein of unknown function, DUF (PF04219; HMM-score: 13.1)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.131
    • Ymax_pos: 11
    • Cmax: 0.106
    • Cmax_pos: 5
    • Smax: 0.198
    • Smax_pos: 4
    • Smean: 0.172
    • D: 0.147
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446007176 NCBI
  • RefSeq: WP_000085031 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MSQYKTKHINDFTKKELQELSSKGQLIDVRHPEEFELGHIKNALLHSVENIETFKQSKNKTYYIYCKSGNRSRKASQFLAQRGYDVVNLDGGYTAYEQQHHNDNLSKVKEDREIKDNRKTFNYSNLQCPGPIVNISKEIKNIAIGDQIEVVVTDHGFLNDIKSWVKQTGHTLVRLNDFGNEIRAIIQKEENKNIEVTHTKSGTTIVLFSGELDKAVAAMIIANGAKAAGRDVTIFCTFWGLNALKKIQSQRIKKKGIAKLFDFMLPNSPINMPISKMNMFGLGNLMMRYVMKKKNVDTLPSLIDQAVEQGVKLIACTMSMDVMGITKEELRDDVEYGGVGAYIGYTEQANHNLFI

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS00250 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]