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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS06560 [old locus tag: SACOL1285 ]
  • pan locus tag?: SAUPAN003567000
  • symbol: nusA
  • pan gene symbol?: nusA
  • synonym:
  • product: transcription termination/antitermination protein NusA

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS06560 [old locus tag: SACOL1285 ]
  • symbol: nusA
  • product: transcription termination/antitermination protein NusA
  • replicon: chromosome
  • strand: +
  • coordinates: 1298387..1299562
  • length: 1176
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (1298387..1299562) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
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    1021
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    1141
    GTGTCAAGTAATGAATTATTATTAGCTACTGAGTATTTAGAAAAAGAAAAGAAGATTCCT
    AGAGCAGTATTAATTGATGCTATTGAAGCAGCTTTAATTACTGCATACAAAAAGAATTAT
    GATAGTGCAAGAAATGTCCGTGTGGAATTAAATATGGATCAAGGTACTTTCAAAGTTATC
    GCTCGTAAAGATGTTGTTGAAGAAGTATTTGACGACAGAGATGAAGTGGATTTAAGTACA
    GCGCTTGTTAAAAACCCTGCATATGAAATTGGTGATATATACGAAGAAGATGTAACACCT
    AAAGATTTTGGTCGTGTAGGTGCTCAAGCAGCGAAACAAGCAGTAATGCAACGTCTTCGT
    GATGCTGAACGTGAAATTTTATTTGAAGAATTTATAGACAAAGAAGAAGACATACTTACT
    GGAATTATTGACCGTGTTGACCATCGTTATGTATATGTGAATTTAGGTCGTATCGAAGCT
    GTTTTATCTGAAGCAGAAAGAAGTCCTAACGAAAAATATATTCCTAACGAACGTATCAAA
    GTATATGTTAACAAAGTGGAACAAACGACAAAAGGTCCTCAAATCTATGTTTCTCGTAGC
    CATCCAGGTTTATTAAAACGTTTATTTGAACAAGAAGTTCCAGAAATTTACGATGGTACT
    GTAATTGTTAAATCAGTAGCACGTGAAGCTGGCGATCGCTCTAAAATTAGTGTCTTCTCT
    GAAAACAATGATATAGATGCTGTTGGTGCATGTGTTGGTGCTAAAGGCGCACGTGTTGAA
    GCTGTTGTTGAAGAGCTAGGTGGTGAAAAAATCGACATCGTTCAATGGAATGAAGATCCA
    AAAGTATTTGTAAAAAATGCTTTAAGCCCTTCTCAAGTTTTAGAAGTTATTGTTGATGAA
    ACAAATCAATCTACAGTAGTTGTTGTTCCTGATTATCAATTGTCATTAGCGATTGGTAAA
    AGAGGACAAAACGCACGTCTAGCTGCTAAATTAACCGGCTGGAAAATTGATATTAAATCA
    GAAACAGATGCGCGTGAAGCGGGTATCTATCCAGTAGTTGAAGCTGAAAAAGTAACTGAA
    GAAGATGTTGCTTTAGAAGATGCTGACACAACAGAATCAACCGAAGAGGTAAATGATGTT
    TCAGTTGAAACAAATGTAGAGAAAGAATCTGAATAA
    60
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    1176

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS06560 [old locus tag: SACOL1285 ]
  • symbol: NusA
  • description: transcription termination/antitermination protein NusA
  • length: 391
  • theoretical pI: 4.30093
  • theoretical MW: 43740.7
  • GRAVY: -0.409974

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    Genetic information processingTranscriptionTranscription factorstranscription termination factor NusA (TIGR01953; HMM-score: 407.1)
    NusA family KH domain protein, archaeal (TIGR01952; HMM-score: 53.2)
    Rhs element Vgr protein (TIGR01646; HMM-score: 15.1)
  • TheSEED:
  • PFAM:
    no clan definedNusA_N; NusA N-terminal domain (PF08529; HMM-score: 130.8)
    KH (CL0007) KH_5; NusA-like KH domain (PF13184; HMM-score: 101.3)
    OB (CL0021) S1; S1 RNA binding domain (PF00575; HMM-score: 24.4)
    KH (CL0007) KH_2; KH domain (PF07650; HMM-score: 17.7)
    KH_1; KH domain (PF00013; HMM-score: 16.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.119
    • Ymax_pos: 15
    • Cmax: 0.105
    • Cmax_pos: 43
    • Smax: 0.183
    • Smax_pos: 8
    • Smean: 0.136
    • D: 0.126
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446019607 NCBI
  • RefSeq: WP_000097462 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MSSNELLLATEYLEKEKKIPRAVLIDAIEAALITAYKKNYDSARNVRVELNMDQGTFKVIARKDVVEEVFDDRDEVDLSTALVKNPAYEIGDIYEEDVTPKDFGRVGAQAAKQAVMQRLRDAEREILFEEFIDKEEDILTGIIDRVDHRYVYVNLGRIEAVLSEAERSPNEKYIPNERIKVYVNKVEQTTKGPQIYVSRSHPGLLKRLFEQEVPEIYDGTVIVKSVAREAGDRSKISVFSENNDIDAVGACVGAKGARVEAVVEELGGEKIDIVQWNEDPKVFVKNALSPSQVLEVIVDETNQSTVVVVPDYQLSLAIGKRGQNARLAAKLTGWKIDIKSETDAREAGIYPVVEAEKVTEEDVALEDADTTESTEEVNDVSVETNVEKESE

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • nusA no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]