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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS06960 [old locus tag: SACOL1367 ]
  • pan locus tag?: SAUPAN003706000
  • symbol: SACOL_RS06960
  • pan gene symbol?:
  • synonym:
  • product: gamma-aminobutyrate permease

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS06960 [old locus tag: SACOL1367 ]
  • symbol: SACOL_RS06960
  • product: gamma-aminobutyrate permease
  • replicon: chromosome
  • strand: -
  • coordinates: 1372142..1373596
  • length: 1455
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (1372142..1373596) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    ATGGAAGATAATAAAATGAACCGTAGTCTTAACTCAAGACACATTTCCATGATTGCTATA
    GGTGGTGCAATTGGGACTGGTCTATTTGTAGCTACTGGTAATATCATTTCTCAAGCTGGT
    CCTGGAGGCGCTATACTCGCTTATCTTGTTATTGGTGTCATGCTATATTTCTTAATGTCA
    TCAATTGGAGAGTTGGCAACATTTTATCCAGTATCAGGTTCATTCAGCTCTTATTCAACA
    CGCTTTATTGACTCATCTCTTGGCTTTACCATGGGATGGTTGTATTGGGCATTGTGGTCA
    TTAGTTACAAGTGTTGATGTCATAGTAGCGTCAAATGTGCTTTATTTCTGGGACACATTT
    AAATTTTTCCACCCCATTACTTGGAGCTTAATCTTTATTACAATTTTACTATTATTAAAC
    ATTTTTTCTGTAAAATCATTTGGAGAAACTGAGTTTTGGTTATCATTGATTAAAGTGTTA
    ACAATTATCGTATTCGTTATTTTTGGCTTTTTAATGATTTTCGGTATCTTAGGTGGTCAT
    ACATATGGATTTGAAAACTATACAAAAGGCCAAGCACCGTTTGTTGGTGGTATCTCTGGT
    TTCTTAGGCGTATTATTAGTCGCCGGATTTTCGGTTGGTGGTACAGAAGTAGTAGCAGTA
    ACTGCTGGTGAATCAGATGACCCTAAAAAGTCTATGCCTAAGGCAATTAAACAAGTATTT
    TGGCGTATTCTTTTATTCTATGTCTTATCAATTGCAGTAATTGGTGCAATTATTCCGTAC
    ACAGATCCATCATTATTAAGAGCAAGTAGTTCAATAAGTCAAAGCCCATTTACAATTGTA
    TTCGATAGAGTAGGCATAGCCTTTGCAGCATCAGTAATCAACGCGGTTATTTTAACTTCA
    TTATTATCCGCTGCAAATTCAGGTGTTTATACAACAGGCAGAATGTTGTATTCCTTAAGT
    TCAGACAAAAAAGCACCCCAATTTTTAAGTAAATTAAACAAGACAACTAAGTTACCTTTA
    AGAGCATTATTAACTACTTATGCAGTCGTTGTTATTGTTATTATTTATGCAAACTTTAAT
    TCAAATGCCGTTTTTAATTTACTTGAAATTATTGGTTCAATGATTATAGTTGTTTGGGGA
    TCAAGCATTTGGTCACAAATACGATTGCGACAAGCTATTAAAAAACAAGGTCAAGACCCT
    AATAAGGTCCTACCATATAAAGCACCTTTTTATCCATTAGGACCAATCATTGTCATCACT
    ACACTATTATTCTTGCTATTTGGTGGCTCAGTTGAATATATTTTAAAAGATCAATGGTTA
    AATGCTTTTAAAAACTTTTTACCTTTAATCATTCTAGCGTTGATTTACTTTATTCATAAA
    ATCATTCACAAAACAAAATTTGTAAAGCTAGAAACAATTAATTTAAAACCACACGATTAT
    GACAATCAAAAATAA
    60
    120
    180
    240
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    360
    420
    480
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    720
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    840
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    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1455

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS06960 [old locus tag: SACOL1367 ]
  • symbol: SACOL_RS06960
  • description: gamma-aminobutyrate permease
  • length: 484
  • theoretical pI: 10.0022
  • theoretical MW: 53412.7
  • GRAVY: 0.676653

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesamino acid permease (yeast) (TIGR00913; HMM-score: 396.2)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesGABA permease (TIGR01773; HMM-score: 310.7)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesamino acid transporter (TIGR00909; HMM-score: 106.7)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminestransporter, basic amino acid/polyamine antiporter (APA) family (TIGR00905; HMM-score: 77.7)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesethanolamine permease (TIGR00908; HMM-score: 62.3)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminescationic amino acid transport permease (TIGR00906; HMM-score: 54.8)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesL-type amino acid transporter (TIGR00911; HMM-score: 51.6)
    MetabolismTransport and binding proteinsAmino acids, peptides and aminesarginine-ornithine antiporter (TIGR03810; HMM-score: 51.5)
  • TheSEED:
  • PFAM:
    APC (CL0062) AA_permease; Amino acid permease (PF00324; HMM-score: 409.2)
    AA_permease_2; Amino acid permease (PF13520; HMM-score: 154.5)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 12
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.216
    • Ymax_pos: 31
    • Cmax: 0.225
    • Cmax_pos: 40
    • Smax: 0.473
    • Smax_pos: 22
    • Smean: 0.321
    • D: 0.257
  • predicted transmembrane helices (TMHMM): 11

Accession numbers[edit source | edit]

  • GI: 446312101 NCBI
  • RefSeq: WP_000389956 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MEDNKMNRSLNSRHISMIAIGGAIGTGLFVATGNIISQAGPGGAILAYLVIGVMLYFLMSSIGELATFYPVSGSFSSYSTRFIDSSLGFTMGWLYWALWSLVTSVDVIVASNVLYFWDTFKFFHPITWSLIFITILLLLNIFSVKSFGETEFWLSLIKVLTIIVFVIFGFLMIFGILGGHTYGFENYTKGQAPFVGGISGFLGVLLVAGFSVGGTEVVAVTAGESDDPKKSMPKAIKQVFWRILLFYVLSIAVIGAIIPYTDPSLLRASSSISQSPFTIVFDRVGIAFAASVINAVILTSLLSAANSGVYTTGRMLYSLSSDKKAPQFLSKLNKTTKLPLRALLTTYAVVVIVIIYANFNSNAVFNLLEIIGSMIIVVWGSSIWSQIRLRQAIKKQGQDPNKVLPYKAPFYPLGPIIVITTLLFLLFGGSVEYILKDQWLNAFKNFLPLIILALIYFIHKIIHKTKFVKLETINLKPHDYDNQK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS06960 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]