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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS07475 [old locus tag: SACOL1465 ]
  • pan locus tag?: SAUPAN003861000
  • symbol: SACOL_RS07475
  • pan gene symbol?: cvfC
  • synonym:
  • product: virulence factor C

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS07475 [old locus tag: SACOL1465 ]
  • symbol: SACOL_RS07475
  • product: virulence factor C
  • replicon: chromosome
  • strand: -
  • coordinates: 1476298..1477422
  • length: 1125
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (1476298..1477422) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGGAAATTTTACGTATAGAGCCAACACCAAGTCCAAATACAATGAAAGTTGTTTTGTCA
    TATACAAGAGAAGACAAGTTATCTAATACTTATAAAAAAGTAGAAGAAACACAACCAAGA
    TTTATAAATCAGTTGTTATCTATAGATGGTATCACTTCCATTTTTCATGTCATGAACTTC
    TTAGCTGTTGATAAGGCACCAAAAGCTGATTGGGAAGTCATATTACCTGATATTAAAGCT
    GCTTTTTCTGATGCGAATAAGGTTTTAGAATCTGTAAATGAACCTCAAATTGACAATCAT
    TTTGGTGAAATTAAAGCTGAATTATTAACTTTTAAGGGTATACCGTATCAAATTAAGCTA
    ACTTCTGCTGACCAAGAATTAAGAGAACAATTACCACAAACATATGTTGACCATATGACT
    CAAGCGCAAACAGCACATGACAATATTGTTTTTATGCGTAAATGGCTAGATTTAGGAAAT
    CGCTATGGAAATATTCAAGAAGTAATGGATGGTGTCCTAGAAGAAGTGCTAGCTACCTAT
    CCAGAATCACAGTTACCCGTATTGGTAAAACATGCTTTAGAAGAAAATCACGCAACTAAT
    AATTATCATTTCTATCGACATGTCTCTTTGGATGAATATCATGCAACTGATAATTGGAAG
    ACTCGATTACGAATGTTAAACCATTTTCCAAAGCCGACTTTTGAAGATATACCGCTGCTT
    GATTTAGCTTTATCTGATGAAAAAGTACCGGTTAGACGTCAAGCGATTGTATTATTAGGT
    ATGATTGAAAGTAAAGAAATTTTACCGTATTTATATAAGGGGCTTCGTGATAAAAGTCCT
    GCTGTAAGAAGAACAGCAGGGGATTGCATAAGCGATTTAGGGTATCCAGAGGCACTACCA
    GAAATGGTGCTACTATTAGATGATCCACAGAAAATCGTTAGGTGGCGTGCTGCTATGTTT
    ATCTTTGATGAAGGTAATGCAGAGCAGCTTCCCGCACTAAAAGCCCATATTAATGACAAT
    GCGTTTGAAGTTAAATTACAAATTGAAATGGCCATATCTCGTATTGAAAACGGAGATGAA
    GCACTTGGTTCAGTATGGAAACAAATGGCAAACAGAACAATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1125

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS07475 [old locus tag: SACOL1465 ]
  • symbol: SACOL_RS07475
  • description: virulence factor C
  • length: 374
  • theoretical pI: 5.09121
  • theoretical MW: 42922.9
  • GRAVY: -0.338235

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:
  • PFAM:
    no clan definedVirulence_fact; Virulence factor (PF13769; HMM-score: 89)
    Nfu_N; Scaffold protein Nfu/NifU N terminal (PF08712; HMM-score: 64.4)
    TPR (CL0020) HEAT_2; HEAT repeats (PF13646; HMM-score: 53.8)
    HEAT_EZ; HEAT-like repeat (PF13513; HMM-score: 32.6)
    HEAT; HEAT repeat (PF02985; HMM-score: 32.4)
    Cnd1; non-SMC mitotic condensation complex subunit 1 (PF12717; HMM-score: 27.1)
    HEAT_PBS; PBS lyase HEAT-like repeat (PF03130; HMM-score: 17.3)
    no clan definedDUF4088; Protein of unknown function (DUF4088) (PF13317; HMM-score: 12.5)
    TPR (CL0020) Adaptin_N; Adaptin N terminal region (PF01602; HMM-score: 10.7)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.127
    • Ymax_pos: 14
    • Cmax: 0.111
    • Cmax_pos: 69
    • Smax: 0.227
    • Smax_pos: 5
    • Smean: 0.164
    • D: 0.141
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446326795 NCBI
  • RefSeq: WP_000404650 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MEILRIEPTPSPNTMKVVLSYTREDKLSNTYKKVEETQPRFINQLLSIDGITSIFHVMNFLAVDKAPKADWEVILPDIKAAFSDANKVLESVNEPQIDNHFGEIKAELLTFKGIPYQIKLTSADQELREQLPQTYVDHMTQAQTAHDNIVFMRKWLDLGNRYGNIQEVMDGVLEEVLATYPESQLPVLVKHALEENHATNNYHFYRHVSLDEYHATDNWKTRLRMLNHFPKPTFEDIPLLDLALSDEKVPVRRQAIVLLGMIESKEILPYLYKGLRDKSPAVRRTAGDCISDLGYPEALPEMVLLLDDPQKIVRWRAAMFIFDEGNAEQLPALKAHINDNAFEVKLQIEMAISRIENGDEALGSVWKQMANRTI

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS07475 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]