From AureoWiki
Jump to: navigation, search
NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS12180 [old locus tag: SACOL2316 ]
  • pan locus tag?: SAUPAN005803000
  • symbol: SACOL_RS12180
  • pan gene symbol?: glvC
  • synonym:
  • product: PTS alpha-glucoside transporter subunit IIBC

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS12180 [old locus tag: SACOL2316 ]
  • symbol: SACOL_RS12180
  • product: PTS alpha-glucoside transporter subunit IIBC
  • replicon: chromosome
  • strand: -
  • coordinates: 2376088..2377692
  • length: 1605
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (2376088..2377692) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGAATGCGATAAAGCGTTTCGGTAGTGCAATGATTGTACCGGTATTAATGTTCGCTTTC
    TTTGGGATAGTGCTTGGCTTTGCGACATTATTTAAAAATCCTACAATCATGGGGAGTTTA
    GCAGATCAACATACGTTTTGGTTTAAATTTTGGTCAGTAATAGAATCTGGTGGCTGGGTT
    ATTTTTACGCATATGGAAGTTGTATTTGTTGTAGGTCTACCACTTTCTTTAGCTAAAAAA
    GCACCAGGTCATGCAGCACTTGCAGCATTGATGGGTTACTTAATGTTTAATACATTTATA
    AATGCCATTTTAACACAATGGCCACATACGTTTGGCGCTAATTTAGAAAAAGGCGTTGAA
    AATGTACCTGGTTTAAAATCAATTGCAGGTATTGCCACATTGGATACGAATATTCTAGGT
    GGTATTATTATTTCAGCTATTATTACTTGGATTCACAATAGATACTATAGTAAACGATTA
    CCAGAAATGGTTGGTGTATTCCAAGGTTTAACATTTGTAGTTACGATTTCATTTTTTGTG
    ATGTTACCATTAGCAGCAATTACTTGTGTTATTTGGCCAACTGTTCAGCACGGTATTGGT
    TCAATGCAACACTTTATCATTGCTTCAGGCTATATCGGTGTATGGTTGTATCACTTCTTA
    GAACGTGTATTAATACCAACAGGATTACATCACTTTATTTATGCACCAATTGAAGTTGGA
    CCAGTAGTAGTCAATCACGGCTTGAAAGCTGAATGGTTACAACATTTAAATGAGTTTGCT
    AAGAGTACTAAGCCATTAAAAGAGCAATTCCCTTATGGCTTTATGCTTCAAGGAAATGGG
    AAAGTATTTGGATGTTTAGGTATTGCTTTAGCAATGTATGCTACGACACCTAAAGAAAAT
    CGTAAAAAGGTGGCGGCACTACTTATTCCTGCCACATTAACAGCAGTCGTTGTAGGTATT
    ACTGAGCCATTAGAGTTTACATTCTTATTCATCGCACCATACTTATTTGTTTTACACGCA
    GTTTTAGCAGCTTCAATGGATACTTTAATGTACGCATTTGGTGTTGTAGGTAACATGGGT
    GGTGGCTTGTTAGACTTTATTTCAACAAACTGGTTGCCATTAGGTAAAGAACATTGGGGT
    ACTTATGTTGCACAAGTTATTATCGGTCTGATATTTGTAGCGATTTACTTCTTCTTATTC
    AGATTCTTAATTTTGAAATTTGATATTCCATTACCTGGACGTAAGAAAACAGAAGAGGAA
    GTTAAATTATTTTCTAAGCAAGATTACAAAAATAAAAAAGGTGATAGCGTAGATTCTAAA
    CGTGCTTCATCTGGTAATGAATACGAAGACAAAGCTGCATATTACCTCGACGGTTTAGGC
    GGCAAAGAAAATATCAAAGATGTTACTAACTGTACAACAAGATTACGCTTAACTGTTTAT
    GATGAAAGTAAAGTTGCAGATACGGAATATTTCACGCATCAACAAATGGCACACGGATTA
    GTAAAGAGTGGTAAGAGTATCCAAGTTGTAGTAGGTATGACAGTACCACAAGTTCGTGAA
    GCATTTGAACAAATGGTTGAGGATCAATCGCCCGAAGATAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1605

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS12180 [old locus tag: SACOL2316 ]
  • symbol: SACOL_RS12180
  • description: PTS alpha-glucoside transporter subunit IIBC
  • length: 534
  • theoretical pI: 8.64496
  • theoretical MW: 59339.2
  • GRAVY: 0.364607

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidsPTS system, alpha-glucoside-specific IIBC component (TIGR02005; EC 2.7.1.69; HMM-score: 966.1)
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidsPTS system, maltose and glucose-specific IIBC component (TIGR02004; EC 2.7.1.69; HMM-score: 290.6)
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidsPTS system, glucose-specific IIBC component (TIGR02002; EC 2.7.1.69; HMM-score: 278.1)
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidsPTS system, N-acetylglucosamine-specific IIBC component (TIGR01998; EC 2.7.1.69; HMM-score: 277.2)
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidsPTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 237.7)
    Signal transductionSignal transductionPTSPTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 237.7)
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidsPTS system, IIBC component (TIGR02003; EC 2.7.1.69; HMM-score: 161.9)
    PTS system, beta-glucoside-specific IIABC component (TIGR01995; EC 2.7.1.69; HMM-score: 58.3)
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidsPTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 56)
    Signal transductionSignal transductionPTSPTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 56)
    PTS system, sucrose-specific IIBC component (TIGR01996; EC 2.7.1.69; HMM-score: 52.8)
    PTS system, trehalose-specific IIBC component (TIGR01992; EC 2.7.1.69; HMM-score: 50.2)
  • TheSEED:
  • PFAM:
    PTS_EIIC (CL0493) PTS_EIIC; Phosphotransferase system, EIIC (PF02378; HMM-score: 221.7)
    no clan definedPTS_EIIB; phosphotransferase system, EIIB (PF00367; HMM-score: 53.9)
    Ldr_toxin; Toxin Ldr, type I toxin-antitoxin system (PF13940; HMM-score: 12.5)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.247
    • Ymax_pos: 20
    • Cmax: 0.153
    • Cmax_pos: 42
    • Smax: 0.556
    • Smax_pos: 1
    • Smean: 0.466
    • D: 0.333
  • predicted transmembrane helices (TMHMM): 10

Accession numbers[edit source | edit]

  • GI: 446914245 NCBI
  • RefSeq: WP_000991501 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MNAIKRFGSAMIVPVLMFAFFGIVLGFATLFKNPTIMGSLADQHTFWFKFWSVIESGGWVIFTHMEVVFVVGLPLSLAKKAPGHAALAALMGYLMFNTFINAILTQWPHTFGANLEKGVENVPGLKSIAGIATLDTNILGGIIISAIITWIHNRYYSKRLPEMVGVFQGLTFVVTISFFVMLPLAAITCVIWPTVQHGIGSMQHFIIASGYIGVWLYHFLERVLIPTGLHHFIYAPIEVGPVVVNHGLKAEWLQHLNEFAKSTKPLKEQFPYGFMLQGNGKVFGCLGIALAMYATTPKENRKKVAALLIPATLTAVVVGITEPLEFTFLFIAPYLFVLHAVLAASMDTLMYAFGVVGNMGGGLLDFISTNWLPLGKEHWGTYVAQVIIGLIFVAIYFFLFRFLILKFDIPLPGRKKTEEEVKLFSKQDYKNKKGDSVDSKRASSGNEYEDKAAYYLDGLGGKENIKDVTNCTTRLRLTVYDESKVADTEYFTHQQMAHGLVKSGKSIQVVVGMTVPQVREAFEQMVEDQSPEDK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS12180 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]