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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus COL
  • locus tag: SACOL_RS12300 [old locus tag: SACOL2342 ]
  • pan locus tag?: SAUPAN005846000
  • symbol: SACOL_RS12300
  • pan gene symbol?: corA
  • synonym:
  • product: cobalt transporter CorA

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SACOL_RS12300 [old locus tag: SACOL2342 ]
  • symbol: SACOL_RS12300
  • product: cobalt transporter CorA
  • replicon: chromosome
  • strand: -
  • coordinates: 2402115..2403062
  • length: 948
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002951 (2402115..2403062) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGCTTTAAAGATACGGTATCAAACTACATATGAACCGTTTAAAGTAGTTGATGATATC
    AAAGAGATACCAAAAGATGCGACTATTGTTTGGTATGATTTTGATGAACCGAATGAACAA
    GAAAATGAATGGTTTAAAGCACATTTTAATTTTAATGATTTAGAAGTGGATGATGCAATT
    AACGGTATGCCACGAGCTAAATATAAATCTTATAAAGATTATCAATACTTAGTATTCCAT
    AGTATTATGGGGTCAAACTATTCACCAATAGCACTAAATATTTTTATACAAGACAATGTA
    TTAGTAACATATCATCATCAAACGTTGGAATCATTAAATAAAGTAGTCTATAAGTATATG
    AATACATTAGATGCAGAATTAGATTGTGCAGATGTCGTCATATTAATTTTAGATATGATG
    GTTGATAAATATTTCAACTTTGTATATGCACTTGAAGATAGTGTTTATCATTTTGAAGAC
    CGCCATGTAGATGATCGCTTTAATAAAATGGTCATGGATAGTGTCTTTAAGTTACGTTCG
    GATTTGATTAAAGTAAAACGTGTACTGTTTCCTATGCAAGAGCTAATTGATACAATGAAA
    CAAAATGGTGATTTGATTATAGATAATAAACATTCGCTATACATTCAACATATCGATGAC
    CACTTGATTAAGCAACGTAATATCATTCGTACTGCTCAAGAAATGACAAACGAAATACGA
    GAAAATTTTGAGTCATACACGTCATTTAGAATGAATAGTATTATGCAAGTACTGACATTA
    GTATCAGTTATATTTTCACCGTTAACATTCATAGCTGGGATTTATGGTATGAACTTTGTA
    AATATGCCGGCATTACATTTACATTATGGATATTATATTTGCTTAGCTGTAATGTTTGTT
    ATAGCTGTCGTATTAATCATCTTTTTCAGACGTAAAAAATGGTTTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    948

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SACOL_RS12300 [old locus tag: SACOL2342 ]
  • symbol: SACOL_RS12300
  • description: cobalt transporter CorA
  • length: 315
  • theoretical pI: 5.76074
  • theoretical MW: 37526.2
  • GRAVY: -0.067619

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsCations and iron carrying compoundsmagnesium and cobalt transport protein CorA (TIGR00383; HMM-score: 206.9)
  • TheSEED:
  • PFAM:
    no clan definedCorA; CorA-like Mg2+ transporter protein (PF01544; HMM-score: 244.6)
    DUF2207; Predicted membrane protein (DUF2207) (PF09972; HMM-score: 17.9)
    Transporter (CL0375) Claudin_2; PMP-22/EMP/MP20/Claudin tight junction (PF13903; HMM-score: 13.9)
    GAG-polyprotein (CL0523) Retrotran_gag_2; gag-polypeptide of LTR copia-type (PF14223; HMM-score: 13.5)
    no clan definedSlyX; SlyX (PF04102; HMM-score: 13.4)
    Tetraspannin (CL0347) Tetraspannin; Tetraspanin family (PF00335; HMM-score: 11.2)
    RND_permease (CL0322) MMPL; MMPL family (PF03176; HMM-score: 8)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.04
    • Cytoplasmic Membrane Score: 9.96
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 2
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.102
    • Ymax_pos: 11
    • Cmax: 0.107
    • Cmax_pos: 48
    • Smax: 0.13
    • Smax_pos: 1
    • Smean: 0.102
    • D: 0.102
  • predicted transmembrane helices (TMHMM): 2

Accession numbers[edit source | edit]

  • GI: 447108175 NCBI
  • RefSeq: WP_001185431 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MALKIRYQTTYEPFKVVDDIKEIPKDATIVWYDFDEPNEQENEWFKAHFNFNDLEVDDAINGMPRAKYKSYKDYQYLVFHSIMGSNYSPIALNIFIQDNVLVTYHHQTLESLNKVVYKYMNTLDAELDCADVVILILDMMVDKYFNFVYALEDSVYHFEDRHVDDRFNKMVMDSVFKLRSDLIKVKRVLFPMQELIDTMKQNGDLIIDNKHSLYIQHIDDHLIKQRNIIRTAQEMTNEIRENFESYTSFRMNSIMQVLTLVSVIFSPLTFIAGIYGMNFVNMPALHLHYGYYICLAVMFVIAVVLIIFFRRKKWF

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SACOL_RS12300 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]