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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 03-AUG-2016

Summary[edit source | edit]

  • organism: Staphylococcus aureus NCTC8325
  • locus tag: SAOUHSC_00062
  • pan locus tag?: SAUPAN000903000
  • symbol: SAOUHSC_00062
  • pan gene symbol?:
  • synonym:
  • product: hypothetical protein

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAOUHSC_00062
  • symbol: SAOUHSC_00062
  • product: hypothetical protein
  • replicon: chromosome
  • strand: -
  • coordinates: 68201..69073
  • length: 873
  • essential: no DEG other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGAATAAACTTCGAGACACTACTTTTCTATCATATTTATTTACTATCATATTGTGGGGA
    TCTGCATTTCCAATGATAAAGATTGCGTTAAATGATTTTAGTGCAGAATCATTGTCGGCA
    TTTCGTTTAATTTTAGCAACAATAATTCTCTTGCCGTTCGTAATTATAAAGAAATTGCCT
    ACCCCTGAACTAAGAGATATCCCTGTTATTTTTATTTTAGGATTTTGTGGATTTGTGATA
    TATCACACAGCTTTAAATTTTGGTGAAACTTTGATTAGTGCAGGTATATCTGGAATTCTA
    GTCTCTACAACGCCTATTTTTTCTAGTGCTTTAGCTTATATATTTTTAAAAGAGCATTTT
    TCAAAATGGAATTGGTTAAGTTCACTCGTCGCATTTATAGGAATATCCATTATTTCAATA
    AGTAAAGATGATTACACAACTATTAATGTATTAGGTGTTTTTATTATTTTACTTGCATCT
    TTTAGTGAAAGTTTGTATTTTACTTTCCAGAAAAAATACATAGAAAAATACGGCTTCATC
    GCTTTCACACTATATACAATAATGGCAAGCTCACCATTTATGCTTATTTTTATTCCTGAA
    ATCATCAACGATATACACGGCGCCACTTTTACATCAATAGTATCGGTACTTTATTTAGCT
    ATATTCCCTACTATAATTCCATACGTTTTGCTTGCTTATATTGTGAAGTCAGTTGGTGTC
    TCTGATGCAACAATGTCTCTTTATTTAACACCTATCGTTTCTTTATTATTATCTTATCTG
    TTATTAGACGAGCTACCAACAACCCTTGCTATTATAGGCGGAATTATCACTCTACTAGGC
    GTTAGTTTAAGTAACTTCTTTCAAAATACATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    873

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAOUHSC_00062
  • symbol: SAOUHSC_00062
  • description: hypothetical protein
  • length: 290
  • theoretical pI: 6.2511
  • theoretical MW: 32209.2
  • GRAVY: 1.03483

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsAmino acids, peptides and aminescarboxylate/amino acid/amine transporter (TIGR00950; HMM-score: 110.3)
    Hypothetical proteinsConservedTpt phosphate/phosphoenolpyruvate translocator (TIGR00817; HMM-score: 17.9)
    MetabolismTransport and binding proteinsUnknown substrateprotein RarD (TIGR00688; HMM-score: 15.8)
  • TheSEED:  
    RNA MetabolismRNA processing and modificationQueuosine-Archaeosine Biosynthesis Permease of the drug/metabolite transporter (DMT) superfamily 
    Virulence, Disease and DefenseResistance to antibiotics and toxic compoundsCobalt-zinc-cadmium resistance Permease of the drug/metabolite transporter (DMT) superfamily 
  • PFAM:
    DMT (CL0184) EamA; EamA-like transporter family (PF00892; HMM-score: 154.7)
    TPT; Triose-phosphate Transporter family (PF03151; HMM-score: 24.4)
    EmrE; Putative multidrug resistance efflux transporter (PF13536; HMM-score: 20.2)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.146
    • Ymax_pos: 32
    • Cmax: 0.158
    • Cmax_pos: 32
    • Smax: 0.258
    • Smax_pos: 3
    • Smean: 0.147
    • D: 0.147
  • predicted transmembrane helices (TMHMM): 10

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MNKLRDTTFLSYLFTIILWGSAFPMIKIALNDFSAESLSAFRLILATIILLPFVIIKKLPTPELRDIPVIFILGFCGFVIYHTALNFGETLISAGISGILVSTTPIFSSALAYIFLKEHFSKWNWLSSLVAFIGISIISISKDDYTTINVLGVFIILLASFSESLYFTFQKKYIEKYGFIAFTLYTIMASSPFMLIFIPEIINDIHGATFTSIVSVLYLAIFPTIIPYVLLAYIVKSVGVSDATMSLYLTPIVSLLLSYLLLDELPTTLAIIGGIITLLGVSLSNFFQNT

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

  1. Ulrike Mäder, Pierre Nicolas, Maren Depke, Jan Pané-Farré, Michel Debarbouille, Magdalena M van der Kooi-Pol, Cyprien Guérin, Sandra Dérozier, Aurelia Hiron, Hanne Jarmer, Aurélie Leduc, Stephan Michalik, Ewoud Reilman, Marc Schaffer, Frank Schmidt, Philippe Bessières, Philippe Noirot, Michael Hecker, Tarek Msadek, Uwe Völker, Jan Maarten van Dijl
    Staphylococcus aureus Transcriptome Architecture: From Laboratory to Infection-Mimicking Conditions.
    PLoS Genet.: 2016, 12(4);e1005962
    [PubMed:27035918] [WorldCat.org] [DOI] (I e)

Relevant publications[edit source | edit]