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Summary[edit source | edit]

  • pan ID?: SAUPAN006207000
  • symbol?: mvaS
  • description?: hydroxymethylglutaryl-CoA synthase

      descriptions from strain specific annotations:

    • hydroxymethylglutaryl-CoA synthase
    • 3-hydroxy-3-methylglutaryl-CoA synthase
    • HMG-CoA synthase
    • 3-hydroxy-3-methylglutaryl coenzyme A synthase
  • strand?: +
  • coordinates?: 6266953..6268119
  • synteny block?: BlockID0049310
  • occurrence?: in 100% of 32 strains

Orthologs[edit source | edit]

    COL:
    N315:
    SA2334 (mvaS)
    NCTC8325:
    Newman:
    NWMN_2446 (mvaS)
    USA300_FPR3757:
    04-02981:
    SA2981_2482 (mvaS)
    08BA02176:
    C248_2603 (mvaS)
    11819-97:
    MS7_2551
    71193:
    ST398NM01_2596
    ECT-R 2:
    ECTR2_2398
    ED133:
    SAOV_2590
    ED98:
    SAAV_2612
    HO 5096 0412:
    SAEMRSA15_24490 (mvaS)
    JH1:
    SaurJH1_2622
    JH9:
    SaurJH9_2569
    JKD6008:
    SAA6008_02584 (mvaS)
    JKD6159:
    SAA6159_02442 (mvaS)
    LGA251:
    SARLGA251_23210 (mvaS)
    M013:
    M013TW_2518
    MRSA252:
    SAR2626 (mvaS)
    MSHR1132:
    SAMSHR1132_23660
    MSSA476:
    SAS2432
    Mu3:
    SAHV_2530 (mvaS)
    Mu50:
    SAV2546 (mvaS)
    MW2:
    MW2467 (mvaS)
    RF122:
    SAB2420 (mvaS)
    ST398:
    SAPIG2596
    T0131:
    SAT0131_02755
    TCH60:
    HMPREF0772_10645 (mvaS)
    TW20:
    SATW20_26680 (mvaS)
    USA300_TCH1516:
    USA300HOU_2540 (mvaS)
    VC40:
    SAVC_11610

Genome Viewer[edit source | edit]

COL chromosome
N315 chromosome
NCTC8325 chromosome
Newman chromosome
USA300_FPR3757 chromosome

Alignments[edit source | edit]

  • alignment of orthologues:
    CLUSTAL format alignment by MAFFT L-INS-i (v7.205)


    COL             MTIGIDKINFYVPKYYVDMAKLAEARQVDPNKFLIGIGQTEMAVSPVNQDIVSMGANAAK
    N315            MTIGIDKINFYVPKYYVDMAKLAEARQVDPNKFLIGIGQTEMAVSPVNQDIVSMGANAAK
    NCTC8325        MTIGIDKINFYVPKYYVDMAKLAEARQVDPNKFLIGIGQTEMAVSPVNQDIVSMGANAAK
    Newman          MTIGIDKINFYVPKYYVDMAKLAEARQVDPNKFLIGIGQTEMAVSPVNQDIVSMGANAAK
    USA300_FPR3757  MTIGIDKINFYVPKYYVDMAKLAEARQVDPNKFLIGIGQTEMAVSPVNQDIVSMGANAAK
                    ************************************************************

    COL             DIITDEDKKKIGMVIVATESAVDAAKAAAVQIHNLLGIQPFARCFEMKEACYAATPAIQL
    N315            DIITDEDKKKIGMVIVATESAVDAAKAAAVQIHNLLGIQPFARCFEMKEACYAATPAIQL
    NCTC8325        DIITDEDKKKIGMVIVATESAVDAAKAAAVQIHNLLGIQPFARCFEMKEACYAATPAIQL
    Newman          DIITDEDKKKIGMVIVATESAVDAAKAAAVQIHNLLGIQPFARCFEMKEACYAATPAIQL
    USA300_FPR3757  DIITDEDKKKIGMVIVATESAVDAAKAAAVQIHNLLGIQPFARCFEMKEACYAATPAIQL
                    ************************************************************

    COL             AKDYLATRPNEKVLVIATDTARYGLNSGGEPTQGAGAVAMVIAHNPSILALNEDAVAYTE
    N315            AKDYLATRPNEKVLVIATDTARYGLNSGGEPTQGAGAVAMVIAHNPSILALNEDAVAYTE
    NCTC8325        AKDYLATRPNEKVLVIATDTARYGLNSGGEPTQGAGAVAMVIAHNPSILALNEDAVAYTE
    Newman          AKDYLATRPNEKVLVIATDTARYGLNSGGEPTQGAGAVAMVIAHNPSILALNEDAVAYTE
    USA300_FPR3757  AKDYLATRPNEKVLVIATDTARYGLNSGGEPTQGAGAVAMVIAHNPSILALNEDAVAYTE
                    ************************************************************

    COL             DVYDFWRPTGHKYPLVDGALSKDAYIRSFQQSWNEYAKRQGKSLADFASLCFHVPFTKMG
    N315            DVYDFWRPTGHKYPLVDGALSKDAYIRSFQQSWNEYAKRQGKSLADFASLCFHVPFTKMG
    NCTC8325        DVYDFWRPTGHKYPLVDGALSKDAYIRSFQQSWNEYAKRQGKSLADFASLCFHVPFTKMG
    Newman          DVYDFWRPTGHKYPLVDGALSKDAYIRSFQQSWNEYAKRQGKSLADFASLCFHVPFTKMG
    USA300_FPR3757  DVYDFWRPTGHKYPLVDGALSKDAYIRSFQQSWNEYAKRQGKSLADFASLCFHVPFTKMG
                    ************************************************************

    COL             KKALESIIDNADETTQERLRSGYEDAVDYNRYVGNIYTGSLYLSLISLLENRDLQAGETI
    N315            KKALESIIDNADETTQERLRSGYEDAVDYNRYVGNIYTGSLYLSLISLLENRDLQAGETI
    NCTC8325        KKALESIIDNADETTQERLRSGYEDAVDYNRYVGNIYTGSLYLSLISLLENRDLQAGETI
    Newman          KKALESIIDNADETTQERLRSGYEDAVDYNRYVGNIYTGSLYLSLISLLENRDLQAGETI
    USA300_FPR3757  KKALESIIDNADETTQERLRSGYEDAVDYNRYVGNIYTGSLYLSLISLLENRDLQAGETI
                    ************************************************************

    COL             GLFSYGSGSVGEFYSATLVEGYKDHLDQAAHKALLNNRTEVSVDAYETFFKRFDDVEFDE
    N315            GLFSYGSGSVGEFYSATLVEGYKDHLDQAAHKALLNNRTEVSVDAYETFFKRFDDVEFDE
    NCTC8325        GLFSYGSGSVGEFYSATLVEGYKDHLDQAAHKALLNNRTEVSVDAYETFFKRFDDVEFDE
    Newman          GLFSYGSGSVGEFYSATLVEGYKDHLDQAAHKALLNNRTEVSVDAYETFFKRFDDVEFDE
    USA300_FPR3757  GLFSYGSGSVGEFYSATLVEGYKDHLDQAAHKALLNNRTEVSVDAYETFFKRFDDVEFDE
                    ************************************************************

    COL             EQDAVHEDRHIFYLSNIENNVREYHRPE
    N315            EQDAVHEDRHIFYLSNIENNVREYHRPE
    NCTC8325        EQDAVHEDRHIFYLSNIENNVREYHRPE
    Newman          EQDAVHEDRHIFYLSNIENNVREYHRPE
    USA300_FPR3757  EQDAVHEDRHIFYLSNIENNVREYHRPE
                    ****************************