NCBI: 10-JUN-2013

⊟Summary

• organism: Staphylococcus aureus USA300_FPR3757
• locus tag: SAUSA300_0881 [new locus tag: SAUSA300_RS04750 ]
• pan locus tag^?: SAUPAN003121000
• symbol: SAUSA300_0881
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Gene

⊟General

• type: CDS
• locus tag: SAUSA300_0881 [new locus tag: SAUSA300_RS04750 ]
• symbol: SAUSA300_0881
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 968183..969301
• length: 1119
• essential: unknown other strains

⊟Accession numbers

• Gene ID: 3913055 NCBI
• RefSeq: YP_493581 NCBI
• MicrobesOnline: 1292396 MicrobesOnline

⊟Phenotype

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⊟DNA sequence

• 1
  61
  121
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  481
  541
  601
  661
  721
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  841
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  1021
  1081
  
  ATGAATAAGTTAATACTTGGGATTTATTTATACCGAATTTTTTCACGAGCATACTTTTAT
  TTACCGTTTTTATTAATTTACTTTTTGATTCAAGGTTATTCCATAATACAATTAGAAATA
  TTAATGGCGTCTTATGGCATTGCAGCATTTTTATTCTCTCTATACAAAGAGAAGTGTTTT
  AAAATTTGTAACTTAAAAGATTCTAATAAATTAGTTGTTAGTGAAATATTCAAAATCATC
  GGTTTATTGTTGTTATTATATCAAAATCAATATTTAATTTTAGTAGTGGCACAAATATTA
  TTAGGGTTAAGTTACTCAATGATGGCGGGTGTTGATACCGCAATAATTAAAAGAAATATA
  ACAAATGAGAAATACGTACAAAATAAGTCAAATAGCTATATGTTCCTATCATTATTAATT
  TCAGGGATTATAGGTAGTTATCTTTATGGAATAAATATTAAATGGCCTATAATAATGACT
  GGTATATTTTCAATTCTAACAATTATAATTATTCGATGCACATTAGTTGAAAATAGGGAA
  TTAAATTTAATAGGAGAAACAAAGGGAAAGATAAAGAAATTTCTACCAGAAGAGAAGTTT
  TGGATATTGCATTATTCTTTTTTAAGAGCGTTAATATTAGGATTTTTTATAGGATTTATT
  CCAATTAATATATATAATGATTTAAAACTGAATAATTTACAATTTATTTCAGTATTAACT
  TGTTACACAGTTATGGGTTTTGTATCTTCACGTTATTTAACTAAATACTTGAATTATAAG
  TTTGTGTCAGAAATTTGTTTAGTAATATTTTTAATAATATATACATATCAAAGTTTCATA
  GCAGTTACTATTTCTATGATATTTTTAGGTATTTCTTCAGGGTTAACTCGTCCACAAACT
  ATAAATAAACTTTCTAGCAGTAGTAACTTAAGAGTGATGCTTAATTATGCAGAAACGTTA
  TATTTTATTTTTAATATCGCATTTTTACTTATGGGTGGTTACTTATATACAATAGGAACT
  ATTCAATACTTAATATTATTTATTTCGTTATTAATTTTTATATATTTAATAATAATATTT
  TATTTTACAAGGAGAGAGCAACATGAAAATAAAAACTGA
  60
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  1020
  1080
  1119
  

⊟Protein

⊟General

• locus tag: SAUSA300_0881 [new locus tag: SAUSA300_RS04750 ]
• symbol: SAUSA300_0881
• description: hypothetical protein
• length: 372
• theoretical pI: 9.71449
• theoretical MW: 43314.8
• GRAVY: 0.756183

⊟Function

• reaction:
• TIGRFAM:
  multidrug resistance protein (TIGR00880; HMM-score: 27.4)
• TheSEED:  
  Putative uncharacterized protein MW0861 
• PFAM:
  MFS (CL0015) MFS_1; Major Facilitator Superfamily (PF07690; HMM-score: 38.2)

⊟Structure, modifications & interactions

• domains:
• modifications:
• cofactors:
• effectors:
• protein partners:

⊟Localization

• PSORTb: Cytoplasmic Membrane
  • Cytoplasmic Score: 0
  • Cytoplasmic Membrane Score: 10
  • Cellwall Score: 0
  • Extracellular Score: 0
  • Internal Helices: 10
• LocateP: Multi-transmembrane
  • Prediction by SwissProt Classification: Membrane
  • Pathway Prediction: Sec-(SPI)
  • Intracellular Possibility: 0.17
  • Signal Peptide Possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • Ymax: 0.098
  • Ymax_pos: 69
  • Cmax: 0.136
  • Cmax_pos: 44
  • Smax: 0.128
  • Smax_pos: 2
  • Smean: 0.051
  • D: 0.08
• predicted transmembrane helices (TMHMM): 11

⊟Accession numbers

• GI: 87160454 NCBI
• RefSeq: YP_493581 NCBI
• UniProt: A0A0H2XGM3 UniProt

⊟Protein sequence

• MNKLILGIYLYRIFSRAYFYLPFLLIYFLIQGYSIIQLEILMASYGIAAFLFSLYKEKCFKICNLKDSNKLVVSEIFKIIGLLLLLYQNQYLILVVAQILLGLSYSMMAGVDTAIIKRNITNEKYVQNKSNSYMFLSLLISGIIGSYLYGINIKWPIIMTGIFSILTIIIIRCTLVENRELNLIGETKGKIKKFLPEEKFWILHYSFLRALILGFFIGFIPINIYNDLKLNNLQFISVLTCYTVMGFVSSRYLTKYLNYKFVSEICLVIFLIIYTYQSFIAVTISMIFLGISSGLTRPQTINKLSSSSNLRVMLNYAETLYFIFNIAFLLMGGYLYTIGTIQYLILFISLLIFIYLIIIFYFTRREQHENKN

⊟Experimental data

• experimentally validated: no data available

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SAUSA300_0879 > SAUSA300_0880 > SAUSA300_0881 > SAUSA300_0882

⊟Regulation

• sigma factor:
• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Other Information

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