NCBI: 10-JUN-2013

⊟Summary

• organism: Staphylococcus aureus USA300_FPR3757
• locus tag: SAUSA300_1197 [new locus tag: SAUSA300_RS06465 ]
• pan locus tag^?: SAUPAN003622000
• symbol: SAUSA300_1197
• pan gene symbol^?: bsaA
• synonym:
• product: glutathione peroxidase

⊟Gene

⊟General

• type: CDS
• locus tag: SAUSA300_1197 [new locus tag: SAUSA300_RS06465 ]
• symbol: SAUSA300_1197
• product: glutathione peroxidase
• replicon: chromosome
• strand: -
• coordinates: 1319065..1319541
• length: 477
• essential: unknown other strains

⊟Accession numbers

• Gene ID: 3915120 NCBI
• RefSeq: YP_493894 NCBI
• MicrobesOnline: 1292712 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
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  301
  361
  421
  
  ATGGAGACAATTTATGATTTTGTAGTAGAAACAAATAAAGGTGTTACTTACAAATTAGAT
  GCATATAAGGGTGACGTTATGCTAATTGTTAATACAGCTAGCGAATGTGGCTTTACTTCA
  CAATTTGAAGGTTTGCAATCATTATACGAGAAATACAAAGATCAAGGGTTTGTAATTCTA
  GGTTTCCCTTGTAATCAATTTGGTGGCCAAGAACCTGGTTCAGGCGAAGAAGCAGCTCAA
  AACTGTAAATTAAACTATGGTGTTACCTTCCCTATGCATCAAAAAATAGACGTAAAAGGG
  GAACATCAATTACCTTTATTTAGATATTTGACTGCGGCACAACACGGATTCTTTAATGAG
  AAAATCAAATGGAATTTCACTAAGTTTTTAGTGGATCGCGAAGGTAACGTTGTTAAACGA
  TTTGCACCTCAAAAAAAACCTGTTCAAATCGAAAGAGAAATAGAAAAATTATTATAA
  60
  120
  180
  240
  300
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  420
  477
  

⊟Protein

⊟General

• locus tag: SAUSA300_1197 [new locus tag: SAUSA300_RS06465 ]
• symbol: SAUSA300_1197
• description: glutathione peroxidase
• length: 158
• theoretical pI: 6.77696
• theoretical MW: 18117.6
• GRAVY: -0.423418

⊟Function

• reaction:
• TIGRFAM:
  putative glutathione peroxidase Gpx7 (TIGR02540; EC 1.11.1.9; HMM-score: 131.3)
• TheSEED:  
  Stress ResponseOxidative stressGlutathione: Redox cycle Glutathione peroxidase (EC 1.11.1.9) 
  Glutathione: Redox cycle Thioredoxin peroxidase (EC 1.11.1.15) 
• PFAM:
  Thioredoxin (CL0172) GSHPx; Glutathione peroxidase (PF00255; HMM-score: 131.5)
  AhpC-TSA; AhpC/TSA family (PF00578; HMM-score: 25.7)
  Redoxin; Redoxin (PF08534; HMM-score: 19.1)

⊟Structure, modifications & interactions

• domains:
• modifications:
• cofactors:
• effectors:
• protein partners:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helices: 0
• LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular Possibility: 1
  • Signal Peptide Possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • Ymax: 0.125
  • Ymax_pos: 43
  • Cmax: 0.12
  • Cmax_pos: 43
  • Smax: 0.165
  • Smax_pos: 32
  • Smean: 0.093
  • D: 0.113
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 87160345 NCBI
• RefSeq: YP_493894 NCBI
• UniProt: A0A0H2XEC3 UniProt

⊟Protein sequence

• METIYDFVVETNKGVTYKLDAYKGDVMLIVNTASECGFTSQFEGLQSLYEKYKDQGFVILGFPCNQFGGQEPGSGEEAAQNCKLNYGVTFPMHQKIDVKGEHQLPLFRYLTAAQHGFFNEKIKWNFTKFLVDREGNVVKRFAPQKKPVQIEREIEKLL

⊟Experimental data

• experimentally validated: no data available

⊟Expression & Regulation

⊟Operon

• SAUSA300_1197 no polycistronic organisation predicted

⊟Regulation

• sigma factor:
• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: data available for COL

⊟Protein stability

• half-life: no data available

⊟Other Information

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