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Pangenome04-0298108BA0217611819-9771193COLECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50N315NCTC8325NewmanRF122ST398T0131TCH60TW20USA300_FPR3757USA300_TCH1516VC40
NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_1761 [new locus tag: SAUSA300_RS09640 ]
  • pan locus tag?: SAUPAN004573000
  • symbol: epiE
  • pan gene symbol?: epiE
  • synonym:
  • product: lantibiotic epidermin immunity protein F

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAUSA300_1761 [new locus tag: SAUSA300_RS09640 ]
  • symbol: epiE
  • product: lantibiotic epidermin immunity protein F
  • replicon: chromosome
  • strand: -
  • coordinates: 1946369..1947130
  • length: 762
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    ATGATACATTTAAAGATAGAAGGTATCAAATTTAAAAATTCTTTCAGTATGTATGTTTTA
    TTAATAAGTCCGCTGGTATTTCTTTGTTTTGCTATTTTCACAGTCTTATTCGCCAAAAGT
    AATACGGGAACAGCGAATAGTGTGTCACCATATATAACTTTACTATTTAATATTTGGCCA
    ATTGCTTTCATCCCGATTGTATTATGTATGGCTTGTAATTCGTTATTTAAAATTGAAATG
    AGAAATAAATCATTTAATTATTACTTAAGTAATAATTGGTCGATTACAAAAGAAATAAGA
    GCAAAGATTTTCATTTTATCAATAGCATTTTTGGTACATTGCTTTTTAGTATTTATTATT
    GCTTATATAGGTGACCTAATTATTAATCCACATCCGGTTAATGCTATGTTGTTATTGGTG
    ACAATATTGTTGATGTATGTAGTATCTCTACCATTGATACCGCTCAACTTTTTATTAACT
    CGATACTTTGGTGTGTTCGTATCAATATTAATAAACTTAGTATTATCAGTCATTTGTGTC
    TTGTTTTTAACATTGAAGAGTTTATTTTGGGTGTTGCCGTGGGGGATAATGCAGAGAATC
    CCGCTTATTACGCTTGGTATACTACCTAATGGTTTAGTTGTAAACCATAATTCAAAATAC
    TTTAATGATCTCAATGCCTTATATATTTCGATTATTGTTAGCATCATTATTTTCGCGATA
    GTAACATTTTTAAATAATAAGAAAAGTTGGCGATTAAAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    762

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAUSA300_1761 [new locus tag: SAUSA300_RS09640 ]
  • symbol: EpiE
  • description: lantibiotic epidermin immunity protein F
  • length: 253
  • theoretical pI: 10.1479
  • theoretical MW: 28936.2
  • GRAVY: 1.11423

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    lantibiotic protection ABC transporter permease subunit, MutE/EpiE family (TIGR03732; HMM-score: 242.2)
    lantibiotic protection ABC transporter permease subunit, MutG family (TIGR03733; HMM-score: 38)
  • TheSEED:  
    Lantibiotic ABC transporter permease 
  • PFAM:
    ABC-2 (CL0181) ABC2_membrane_4; ABC-2 family transporter protein (PF12730; HMM-score: 23.9)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: 0.5
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.385
    • Ymax_pos: 39
    • Cmax: 0.319
    • Cmax_pos: 39
    • Smax: 0.544
    • Smax_pos: 33
    • Smean: 0.287
    • D: 0.347
  • predicted transmembrane helices (TMHMM): 7

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MIHLKIEGIKFKNSFSMYVLLISPLVFLCFAIFTVLFAKSNTGTANSVSPYITLLFNIWPIAFIPIVLCMACNSLFKIEMRNKSFNYYLSNNWSITKEIRAKIFILSIAFLVHCFLVFIIAYIGDLIINPHPVNAMLLLVTILLMYVVSLPLIPLNFLLTRYFGVFVSILINLVLSVICVLFLTLKSLFWVLPWGIMQRIPLITLGILPNGLVVNHNSKYFNDLNALYISIIVSIIIFAIVTFLNNKKSWRLK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]