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NCBI: 10-JUN-2013

Summary[edit source | edit]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_2313 [new locus tag: SAUSA300_RS12780 ]
  • pan locus tag?: SAUPAN005878000
  • symbol: SAUSA300_2313
  • pan gene symbol?: lctP2
  • synonym:
  • product: L-lactate permease

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAUSA300_2313 [new locus tag: SAUSA300_RS12780 ]
  • symbol: SAUSA300_2313
  • product: L-lactate permease
  • replicon: chromosome
  • strand: -
  • coordinates: 2485913..2487511
  • length: 1599
  • essential: unknown other strains

Accession numbers[edit source | edit]

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    ATGTTAGTAAATACGTTTAACCCATTTGATAATTTATTATTATCGTCTTTAATTGCAGCA
    ATACCGATTGTACTGTTTTTACTATGTTTAACTGTTTTTAAAATGAAAGGTATTTATGCA
    GCTATTACAACACTTGTTGTAACATTACTAATTGCAATACCATTTTTCAAATTGCCAGTT
    GGTATCGCTTCTGGTGCAGTAGTCGAAGGTTTCTTCCAAGGTATCATTCCGATTGGCTAT
    ATCGTTATGATGGCAGTATTGTTATACAAAATTACTGTTGAATCTGGACAATTTTTAACA
    ATTCAAGATAGTATTACAAATATTTCACAAGACCAACGTATTCAAGTTTTACTTATTGGA
    TTTGCATTCAACGCATTTTTAGAAGGTGCAGCAGGATTTGGTGTACCAATTGCAATTTGT
    GCACTTTTATTAACACAATTAGGATTTAATCCATTAAAAGCTGCGATGTTATGTTTAGTC
    GCAAATGCAGCGTCTGGTGCTTTTGGTGCGATTGGTATCCCTGTAGGTGTTGTAGAAACG
    TTGAAATTACCTGGAGATGTTTCAGTATTAGGTGTTTCTCAATCAGCAACTTTAACATTG
    GCAATCATAAATTTCATTATTCCATTCTTACTTATCTTTATTATTGATGGTTTTAGAGGT
    GTTAAAGAAACATTACCAGCAATTTTAGTAGTTTCAATCACTTATACATTTACTCAAGGA
    TTATTAACTGTATTCAGTGGACCTGAATTAGCAGATATTATTCCACCGTTATTAACAATG
    TTAGCATTAGCAGTATTTTCTAAAAAATTCCAACCAAAACACATTTATCGTGTTAATAAA
    GATGAAGAAATTGAACCTGCAAAAGCACATTCTGCAAAAGCAGTATTACATGCATGGAGC
    CCATTCATTGTATTAACAGTCATTGTAATGATTTGGAGTGCGCCATTCTTTAAAAACTTA
    TTCTTACCAAATGGTGCTTTATCATCATTAGTATTTAAATTCAACTTACCTGGAACAATC
    AGCGAAGTTACGCATAAACCATTAGTATTGACTTTAAATATTATTGGACAAACAGGTACA
    GCTATTTTATTAACTATTATTATTACAATTTTAATGTCTAAAAAGGTTAACTTTAAAGAT
    GCAGGTAGATTATTCGGCGTTACATTTAAAGAGTTGTGGTTACCAGTTCTTACAATTTGT
    TTCATCTTAGCAATTTCTAAAATCACAACTTATGGTGGTTTAAGTGCAGCAATGGGTCAA
    GGTATTGCTAAAGCAGGTAATGTCTTCCCAGTTCTATCACCAATTTTAGGTTGGATAGGT
    GTGTTTATGACAGGATCAGTTGTAAATAACAACTCATTATTTGCACCAATTCAAGCTTCT
    GTTGCACAACAAATTGGAACAAGTGGTTCACTTCTTGTATCTGCTAATACAGTTGGTGGT
    GTAGCGGCAAAATTGATTTCACCACAATCAATTGCAATTGCAACTGCAGCAGTAAAACAA
    GTTGGTAAGGAATCAGAATTATTAAAAATGACATTGAAATACAGTGTATGTTTACTAATA
    TTCATCTGTATTTGGACTTTCATCTTGTCATTATTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1599

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAUSA300_2313 [new locus tag: SAUSA300_RS12780 ]
  • symbol: SAUSA300_2313
  • description: L-lactate permease
  • length: 532
  • theoretical pI: 9.63197
  • theoretical MW: 56675.8
  • GRAVY: 1.01523

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsCarbohydrates, organic alcohols, and acidstransporter, lactate permease (LctP) family (TIGR00795; HMM-score: 525.7)
  • TheSEED:  
    L-lactate permease 
  • PFAM:
    IT (CL0182) Lactate_perm; L-lactate permease (PF02652; HMM-score: 533.7)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 13
  • LocateP: Multi-transmembrane
    • Prediction by SwissProt Classification: Membrane
    • Pathway Prediction: Sec-(SPI)
    • Intracellular Possibility: 0.17
    • Signal Peptide Possibility: 0.5
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • Ymax: 0.143
    • Ymax_pos: 41
    • Cmax: 0.25
    • Cmax_pos: 41
    • Smax: 0.26
    • Smax_pos: 3
    • Smean: 0.117
    • D: 0.133
  • predicted transmembrane helices (TMHMM): 13

Accession numbers[edit source | edit]

Protein sequence[edit source | edit]

  • MLVNTFNPFDNLLLSSLIAAIPIVLFLLCLTVFKMKGIYAAITTLVVTLLIAIPFFKLPVGIASGAVVEGFFQGIIPIGYIVMMAVLLYKITVESGQFLTIQDSITNISQDQRIQVLLIGFAFNAFLEGAAGFGVPIAICALLLTQLGFNPLKAAMLCLVANAASGAFGAIGIPVGVVETLKLPGDVSVLGVSQSATLTLAIINFIIPFLLIFIIDGFRGVKETLPAILVVSITYTFTQGLLTVFSGPELADIIPPLLTMLALAVFSKKFQPKHIYRVNKDEEIEPAKAHSAKAVLHAWSPFIVLTVIVMIWSAPFFKNLFLPNGALSSLVFKFNLPGTISEVTHKPLVLTLNIIGQTGTAILLTIIITILMSKKVNFKDAGRLFGVTFKELWLPVLTICFILAISKITTYGGLSAAMGQGIAKAGNVFPVLSPILGWIGVFMTGSVVNNNSLFAPIQASVAQQIGTSGSLLVSANTVGGVAAKLISPQSIAIATAAVKQVGKESELLKMTLKYSVCLLIFICIWTFILSLL

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

Regulation[edit source | edit]

  • sigma factor:
  • regulator: Rex
    Rex (TF) important in Energy metabolism  RegPrecise

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]