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NCBI: 10-JUN-2013

Summary[edit | edit source]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_2400 [new locus tag: SAUSA300_RS13290 ]
  • pan locus tag?: SAUPAN006012000
  • symbol: SAUSA300_2400
  • pan gene symbol?:
  • synonym:
  • product: glutamyl-aminopeptidase

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SAUSA300_2400 [new locus tag: SAUSA300_RS13290 ]
  • symbol: SAUSA300_2400
  • product: glutamyl-aminopeptidase
  • replicon: chromosome
  • strand: -
  • coordinates: 2585499..2586575
  • length: 1077
  • essential: unknown other strains

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGAATCAGTCAGTCAAATTACTTAAACATTTAACAGATGTAAACGGCATTGCTGGTTAT
    GAAATGCAAGTTAAAGAAGCAATGCGTAACTATATAGAGCCTGTCAGTGATCAAATTATT
    GAAGATAACTTGGGTGGCATTTTTGGAAAGAAAAATGCTGAGAATGGTCAATACTCAATT
    ATGATTTCTGGTCATATGGATGAAGTTGGTTTTATGGTAACAAAGATTGATAAACATGGT
    TTTATTTCATTTACGCCAGTTGGTGGATGGTGGAATCAAGTCATGCTATCTCAAAAAGTA
    ACGATTACAACAGATTCGGGCAAAGAAATTAGAGGTATCATCGGTTCTAAACCGCCACAT
    GTCTTAACGCCTGAAGAACGTAAAAAGCCAATGGAAATCAAAAATATGTTTATAGATATT
    GGTGTTAGTAGCAAGGAAGAAGCTGAAGAAGCTGGCGTTGAAGTAGGCAATATGGTTACG
    CCATATAGTGAATTTGAAGTGCTTGCAAATGATAAATATTTAACTGCGAAAGCATTTGAT
    AATCGCTATGGCTGTGCATTAGCTATTGAGGTATTAAAACGTTTAAAAGATGAAAATATT
    GGCATTAACTTATACAGTGGTGCCACAGTGCAAGAAGAAGTTGGTTTGCGTGGTGCGAAA
    GTGGCAGCGAATACGATTAAACCAGACTTGGCGATAGCTGTCGATGTAGGTATTGCTTAT
    GATACCCCAGGTATGTCAGGTCAAACGAGCGATAGTAAACTAGGCGGTGGTCCAGTTGTC
    ATTATGATGGATGCTACAAGTATTGCTCACCAAGGTTTGCGAAAGCATATTAAAGATGTA
    GCTAAGGAACATAACATCGAAGTACAATGGGATACGACACCAGGTGGAGGTACAGATGCG
    GGAAGTATTCATGTCGCAAATGAAGGTATTCCAACGATGACAATCGGTGTTACGCTGCGA
    TACATGCATTCTAATGTTTCAGTGCTCAATGTAGATGATTATGAAAATTCTATCCGTCTT
    GTTACTGAAATTGTCCGTTCATTGAATGATGAAAGTTATAAAAATATCATGTGGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1077

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SAUSA300_2400 [new locus tag: SAUSA300_RS13290 ]
  • symbol: SAUSA300_2400
  • description: glutamyl-aminopeptidase
  • length: 358
  • theoretical pI: 5.03289
  • theoretical MW: 39192.4
  • GRAVY: -0.236592

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Degradation of proteins, peptides, and glycopeptides glutamyl aminopeptidase (TIGR03107; EC 3.4.11.7; HMM-score: 307)
    and 3 more
    hydrolase, peptidase M42 family (TIGR03106; HMM-score: 75.9)
    peptidase T-like protein (TIGR01883; HMM-score: 30.1)
    Metabolism Amino acid biosynthesis Glutamate family acetylornithine deacetylase (ArgE) (TIGR01892; EC 3.5.1.16; HMM-score: 13.7)
  • TheSEED  :
    • M42 glutamyl aminopeptidase, cellulase
  • PFAM:
    Peptidase_MH (CL0035) Peptidase_M42; M42 glutamyl aminopeptidase (PF05343; HMM-score: 393.5)
    and 3 more
    Peptidase_M20; Peptidase family M20/M25/M40 (PF01546; HMM-score: 38.8)
    Peptidase_M28; Peptidase family M28 (PF04389; HMM-score: 26.1)
    Peptidase_M18; Aminopeptidase I zinc metalloprotease (M18) (PF02127; HMM-score: 22.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors: a divalent metal cation
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP: Intracellular
    • Prediction by SwissProt Classification: Cytoplasmic
    • Pathway Prediction: No pathway
    • Intracellular possibility: 1
    • Signal peptide possibility: -1
    • N-terminally Anchored Score: 1
    • Predicted Cleavage Site: No CleavageSite
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00513
    • TAT(Tat/SPI): 0.000392
    • LIPO(Sec/SPII): 0.00083
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MNQSVKLLKHLTDVNGIAGYEMQVKEAMRNYIEPVSDQIIEDNLGGIFGKKNAENGQYSIMISGHMDEVGFMVTKIDKHGFISFTPVGGWWNQVMLSQKVTITTDSGKEIRGIIGSKPPHVLTPEERKKPMEIKNMFIDIGVSSKEEAEEAGVEVGNMVTPYSEFEVLANDKYLTAKAFDNRYGCALAIEVLKRLKDENIGINLYSGATVQEEVGLRGAKVAANTIKPDLAIAVDVGIAYDTPGMSGQTSDSKLGGGPVVIMMDATSIAHQGLRKHIKDVAKEHNIEVQWDTTPGGGTDAGSIHVANEGIPTMTIGVTLRYMHSNVSVLNVDDYENSIRLVTEIVRSLNDESYKNIMW

Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]