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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus USA300_FPR3757
  • locus tag: SAUSA300_RS12610 [old locus tag: SAUSA300_2282 ]
  • pan locus tag?: SAUPAN005823000
  • symbol: SAUSA300_RS12610
  • pan gene symbol?: lyrA
  • synonym:
  • product: lysostaphin resistance protein A

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SAUSA300_RS12610 [old locus tag: SAUSA300_2282 ]
  • symbol: SAUSA300_RS12610
  • product: lysostaphin resistance protein A
  • replicon: chromosome
  • strand: +
  • coordinates: 2454333..2455592
  • length: 1260
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_007793 (2454333..2455592) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGAAGAACAATAAAATTTCTGGTTTTCAATGGGCAATGACGATTTTCGTCTTCTTTGTC
    ATTACAATGGCGTTATCCATTATGCTCAGAGATTTCCAGTCTATAATTGGTGTCAAACAC
    TTTATATTTGAAGTTACAGATCTAGCACCATTAATTGCTGCAATCATTTGTATACTCGTT
    TTCAAATATAAAAAGGTCCAACTTGCAGGTTTAAAATTCTCAATCAGCCTGAAAGTAATT
    GAACGTCTATTGCTAGCTTTAATTTTACCTTTAATTATTCTAATTATTGGTATGTACAGC
    TTTAATACATTTGCAGATAGCTTTATTTTATTACAATCAACAGGCTTATCAGTACCTATT
    ACACACATTCTGATTGGACATATTCTGATGGCGTTCGTAGTAGAATTCGGATTCCGTTCA
    TACTTACAAAATATTGTTGAAACGAAAATGAACACGTTCTTTGCAAGTATTGTTGTTGGT
    TTGATGTATTCAGTTTTCTCAGCAAATACAACTTATGGTACAGAATTTGCTGCTTATAAC
    TTCCTTTATACATTCTCATTCTCTATGATTCTTGGTGAATTAATTAGAGCGACTAAAGGA
    CGTACAATTTATATTGCAACGACATTCCATGCTTCAATGACATTCGGACTTATTTTCTTG
    TTTAGCGAAGAAATCGGCGATCTATTTTCAATCAAAGTCATCGCCATTTCAACAGCAATC
    GTTGCAGTAGGATACATTGGTTTAAGCTTAATTATCCGAGGTATTGCATATTTAACAACA
    AGACGAAACCTTGAAGAACTTGAGCCTAATAATTATTTAGACCATGTCAATGACGATGAA
    GAAACTAATCATACTGAGGCTGAAAAATCTTCTTCAAATATTAAAGATGCTGAAAAAACA
    GGTGTAGCTACTGCATCAACGGTTGGTGTTGCTAAAAATGATACTGAAAATACAGTGGCT
    GACGAACCAAGCATTCATGAAGGTACTGAAAAAACAGAACCTCAACATCACATAGGTAAT
    CAAACTGAATCTAATCATGATGAAGATCATGACATCACTTCGGAGTCAGTAGAATCAGCA
    GAATCAGTTAAACAAGCACCACAAAGTGACGATTTAACAAACGATTCAAATGAAGATGAA
    ATAGAGCAATCATTAAAAGAACCTGCGACTTATAAAGAAGACAGACGTTCATCAGTTGTA
    ATTGATGCAGAAAAACATATCGAAAAAACTGAAGAACAATCTTCAGATAAAAACAAATAA
    60
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    1020
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    1140
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    1260

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SAUSA300_RS12610 [old locus tag: SAUSA300_2282 ]
  • symbol: SAUSA300_RS12610
  • description: lysostaphin resistance protein A
  • length: 419
  • theoretical pI: 4.68169
  • theoretical MW: 46785
  • GRAVY: 0.0937947

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:
  • PFAM:
    no clan definedKinocilin; Kinocilin protein (PF15033; HMM-score: 15.8)
    Peptidase_U (CL0472) Abi; CAAX protease self-immunity (PF02517; HMM-score: 14)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 8
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.145
    • Ymax_pos: 11
    • Cmax: 0.161
    • Cmax_pos: 27
    • Smax: 0.246
    • Smax_pos: 8
    • Smean: 0.207
    • D: 0.169
  • predicted transmembrane helices (TMHMM): 8

Accession numbers[edit source | edit]

  • GI: 446717129 NCBI
  • RefSeq: WP_000794442 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MKNNKISGFQWAMTIFVFFVITMALSIMLRDFQSIIGVKHFIFEVTDLAPLIAAIICILVFKYKKVQLAGLKFSISLKVIERLLLALILPLIILIIGMYSFNTFADSFILLQSTGLSVPITHILIGHILMAFVVEFGFRSYLQNIVETKMNTFFASIVVGLMYSVFSANTTYGTEFAAYNFLYTFSFSMILGELIRATKGRTIYIATTFHASMTFGLIFLFSEEIGDLFSIKVIAISTAIVAVGYIGLSLIIRGIAYLTTRRNLEELEPNNYLDHVNDDEETNHTEAEKSSSNIKDAEKTGVATASTVGVAKNDTENTVADEPSIHEGTEKTEPQHHIGNQTESNHDEDHDITSESVESAESVKQAPQSDDLTNDSNEDEIEQSLKEPATYKEDRRSSVVIDAEKHIEKTEEQSSDKNK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SAUSA300_RS12610 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]