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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS01430 [old locus tag: SA0242 ]
  • pan locus tag?: SAUPAN001124000
  • symbol: SA_RS01430
  • pan gene symbol?: tarJ'
  • synonym:
  • product: ribitol-5-phosphate dehydrogenase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA_RS01430 [old locus tag: SA0242 ]
  • symbol: SA_RS01430
  • product: ribitol-5-phosphate dehydrogenase
  • replicon: chromosome
  • strand: +
  • coordinates: 293627..294652
  • length: 1026
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002745 (293627..294652) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGATTAATCAAGTATATCAACTCGTTGCACCGAGACAGTTCGACGTCACATATAATAAT
    GTTGATATTTATGGTAATCATGTCATCGTAAGACCTTTATACTTGTCTATTTGTGCAGCT
    GATCAAAGGTATTACACAGGTCGAAGAGATGAAAATGTACTGCGCAAAAAATTGCCAATG
    TCATTAGTTCATGAAGCTGTTGGTGAAGTTGTATTCGATAGTAAAGGAGTATTTGAAAAA
    GGTACGAAAGTAGTAATGGTGCCGAATACACCTACAGAGCAACATCATATTATCGCGGAG
    AATTACTTAGCCTCTAGTTATTTTAGATCTAGTGGTTATGATGGTTTTATGCAAGACTAC
    GTTGTGATGGCACATGATCGTATCGTTCCGCTGCCTAATGACATTGATTTGAGTACGATT
    TCATACACAGAGTTAGTGTCAGTAAGTTATCATGCTATACAACGATTTGAACGTAAATCT
    ATACCTTTGAAAAACAGCTTTGGTATTTGGGGTGATGGTAACTTAGGTTATATTACTGCT
    ATTTTGCTACGTAAGTTGTACCCAGAAGCTAAAATTTATGTATTTGGTAAGACAGACTAT
    AAATTAAGTCATTTTTCATTTGTAGATGACATCTTTACAGTAAATCAAATACCAGATGAT
    CTTAAAATTGATCATGCATTTGAATGTGTTGGAGGTAAAGGAAGTCAAGTTGCACTTCAA
    CAAATAGTTGAACATATTTCACCAGAAGGCAGTATTGCTTTGTTAGGCGTAAGTGAATTA
    CCCGTGGAAGTGAATACACGATTAGTACTTGAAAAAGGATTAACGTTGATTGGTAGTAGT
    CGAAGCGGCTCTAAAGATTTTGAGCAAGTTGTTGATTTATATCGTAAGTACCCAGACATA
    GTTGAAAAGTTAGCATTATTAAAAGGACATGAAATTAATGTATGTACGATGCAAGATATC
    GTCCAAGCGTTTGAAATGGATTTATCGACATCTTGGGGAAAAACAGTATTGAAATGGACG
    ATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1026

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA_RS01430 [old locus tag: SA0242 ]
  • symbol: SA_RS01430
  • description: ribitol-5-phosphate dehydrogenase
  • length: 341
  • theoretical pI: 6.18286
  • theoretical MW: 38583
  • GRAVY: -0.0730205

Function[edit source | edit]

  • reaction:
    EC 1.1.1.405?  ExPASy
    Ribitol-5-phosphate 2-dehydrogenase (NADP+)D-ribitol 5-phosphate + NADP+ = D-ribulose 5-phosphate + NADPH
  • TIGRFAM:
    MetabolismEnergy metabolismAmino acids and aminesL-threonine 3-dehydrogenase (TIGR00692; EC 1.1.1.103; HMM-score: 28.7)
    and 1 more
    putative phosphonate catabolism associated alcohol dehydrogenase (TIGR03366; HMM-score: 16.1)
  • TheSEED:
  • PFAM:
    GroES (CL0296) ADH_N; Alcohol dehydrogenase GroES-like domain (PF08240; HMM-score: 36.7)
    NADP_Rossmann (CL0063) ADH_zinc_N; Zinc-binding dehydrogenase (PF00107; HMM-score: 34.2)
    Glu_dehyd_C; Glucose dehydrogenase C-terminus (PF16912; HMM-score: 34)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors: Zn2+
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.101
    • Ymax_pos: 18
    • Cmax: 0.114
    • Cmax_pos: 41
    • Smax: 0.185
    • Smax_pos: 38
    • Smean: 0.096
    • D: 0.099
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446532834 NCBI
  • RefSeq: WP_000610180 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MINQVYQLVAPRQFDVTYNNVDIYGNHVIVRPLYLSICAADQRYYTGRRDENVLRKKLPMSLVHEAVGEVVFDSKGVFEKGTKVVMVPNTPTEQHHIIAENYLASSYFRSSGYDGFMQDYVVMAHDRIVPLPNDIDLSTISYTELVSVSYHAIQRFERKSIPLKNSFGIWGDGNLGYITAILLRKLYPEAKIYVFGKTDYKLSHFSFVDDIFTVNQIPDDLKIDHAFECVGGKGSQVALQQIVEHISPEGSIALLGVSELPVEVNTRLVLEKGLTLIGSSRSGSKDFEQVVDLYRKYPDIVEKLALLKGHEINVCTMQDIVQAFEMDLSTSWGKTVLKWTI

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SA_RS01430 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]