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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS06830 [old locus tag: SA1201 ]
  • pan locus tag?: SAUPAN003764000
  • symbol: SA_RS06830
  • pan gene symbol?: trpD
  • synonym:
  • product: anthranilate phosphoribosyltransferase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA_RS06830 [old locus tag: SA1201 ]
  • symbol: SA_RS06830
  • product: anthranilate phosphoribosyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 1374540..1375538
  • length: 999
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002745 (1374540..1375538) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
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    481
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    901
    961
    ATGACATTACTAACAAGAATAAAAACTGAAACTATATTACTTGAAAGCGACATTAAAGAG
    CTAATCGATATACTTATTTCTCCTAGTATTGGAACTGATATTAAATATGAATTACTTAGT
    TCCTATTCGGAGCGAGAAATCCAACAACAAGAATTAACATATATTGTACGTAGCTTAATT
    AATACAATGTATCCACATCAACCATGTTATGAAGGGGCTATGTGTGTGTGCGGCACAGGT
    GGTGACAAGTCAAATAGTTTCAACATTTCAACGACTGTTGCTTTTGTTGTAGCAAGTGCT
    GGCGTAAAAGTTATAAAACATGGTAATAAAAGTATTACCTCAAATTCAGGTAGTACGGAT
    TTGTTAAATCAAATGAACATACAAACAACAACTGTTGATGATACACCTAACCAATTAAAT
    GAAAAAGACCTTGTATTCATTGGTGCAACTGAATCATATCCAATCATGAAGTATATGCAA
    CCAGTTAGAAAAATGATTGGAAAGCCTACAATATTAAACCTTGTGGGTCCATTAATTAAT
    CCATATCACTTAACGTATCAAATGGTAGGCGTCTTTGATCCTACAAAGTTAAAGTTAGTT
    GCTAAAACGATTAAAGATTTAGGTAGAAAACGTGCAATCGTTTTACATGGTGCAAATGGT
    ATGGATGAAGCAACACTATCTGGTGATAATTTGATATATGAATTGACTGAAGATGGAGAA
    ATCAAAAATTACACATTAAATGCGACTGATTATGGTTTGAAACATGCGCCGAATAGTGAT
    TTTAAAGGCGGTTCACCTGAAGAAAATTTAGCAATCTCCCTTAATATCTTGAATGGTAAA
    GATCAGTCAAGTCGACGTGATGTTGTCTTACTAAATGCGGGTTTAAGCCTTTATGTTGCA
    GAGAAAGTGGATACCATCGCAGAAGGCATAGAACTTGCAACTACATTGATTGATAATGGT
    GAAGCATTGAAAAAATACCATCAAATGAGAGGTGAATAA
    60
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Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA_RS06830 [old locus tag: SA1201 ]
  • symbol: SA_RS06830
  • description: anthranilate phosphoribosyltransferase
  • length: 332
  • theoretical pI: 5.2323
  • theoretical MW: 36525.6
  • GRAVY: -0.195181

Function[edit source | edit]

  • reaction:
    EC 2.4.2.18?  ExPASy
    Anthranilate phosphoribosyltransferaseN-(5-phospho-D-ribosyl)-anthranilate + diphosphate = anthranilate + 5-phospho-alpha-D-ribose 1-diphosphate
  • TIGRFAM:
    MetabolismAmino acid biosynthesisAromatic amino acid familyanthranilate phosphoribosyltransferase (TIGR01245; EC 2.4.2.18; HMM-score: 293.7)
    putative thymidine phosphorylase (TIGR02645; EC 2.4.2.4; HMM-score: 20.6)
    AMP phosphorylase (TIGR03327; EC 2.4.-.-; HMM-score: 20.1)
    MetabolismPurines, pyrimidines, nucleosides, and nucleotidesOtherpyrimidine-nucleoside phosphorylase (TIGR02644; EC 2.4.2.2; HMM-score: 17.6)
  • TheSEED:
  • PFAM:
    no clan definedGlycos_transf_3; Glycosyl transferase family, a/b domain (PF00591; HMM-score: 265.5)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors: Mg2+
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.114
    • Ymax_pos: 13
    • Cmax: 0.124
    • Cmax_pos: 32
    • Smax: 0.148
    • Smax_pos: 5
    • Smean: 0.129
    • D: 0.12
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit source | edit]

  • GI: 446095978 NCBI
  • RefSeq: WP_000173833 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MTLLTRIKTETILLESDIKELIDILISPSIGTDIKYELLSSYSEREIQQQELTYIVRSLINTMYPHQPCYEGAMCVCGTGGDKSNSFNISTTVAFVVASAGVKVIKHGNKSITSNSGSTDLLNQMNIQTTTVDDTPNQLNEKDLVFIGATESYPIMKYMQPVRKMIGKPTILNLVGPLINPYHLTYQMVGVFDPTKLKLVAKTIKDLGRKRAIVLHGANGMDEATLSGDNLIYELTEDGEIKNYTLNATDYGLKHAPNSDFKGGSPEENLAISLNILNGKDQSSRRDVVLLNAGLSLYVAEKVDTIAEGIELATTLIDNGEALKKYHQMRGE

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SA_RS06830 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]