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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS11460 [old locus tag: SA1990 ]
  • pan locus tag?: SAUPAN005584000
  • symbol: SA_RS11460
  • pan gene symbol?:
  • synonym:
  • product: alpha/beta hydrolase

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA_RS11460 [old locus tag: SA1990 ]
  • symbol: SA_RS11460
  • product: alpha/beta hydrolase
  • replicon: chromosome
  • strand: -
  • coordinates: 2261522..2262406
  • length: 885
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002745 (2261522..2262406) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGGGAGTTAAAAGTGTGAAGAAAATTTTTGTAATTATTACGACATTGTTAGCGGTCGCT
    ATTATTATAGGCTCTATTATTACGGTGGTGTTTAGTCAACGACAGGCACAAACATTTAAA
    ATACAACAACAGCAATTTGTTAAAAAGCCAATTCCAACATTGTTCTTACATGGATTTGGT
    GGTAGTGCCAATTCTGAAAAGTTTATGGTGAAGCAAGCAGAAAAAAGAGGGGTAACTAAA
    GATATCATCACTGCTTACGTTTCAAAGGATGGTGCAGTGACATTTAAAGGGAAACTAAGA
    AAAGATGCAGTGAATCCTATTGTGAAAATTGAACTTGAAAATAACAGACAAGGCTATTTG
    GATAAGAATGCTGCGTGGTTTAAAAATGTACTGACTAAGTTACAATCTGAATACAATTTC
    GATAAATTCAACTTTGTCGGTCACTCAATGGGGAACTTAACATTTGCACAATATATGATG
    ACATATGGTAACGACAAGTCACTGCCACAGTTAAACAAACAAGTGAATATTGCAGGGACA
    TTTAATGGTGTTTTAAATATGAATGAAGATGTCAATGAAATTACAGTTGATAAAGATGGT
    AAACCAAGTCGAATGAATCAACCTTATCAGCAATTACGCGTGCTAAAAGATATTTATAAA
    GGTAAAGGTATCGAAGTGCTAAATATTTATGGAGATTTGAAAGATGGTACACATTCAGAC
    GGCAGAGTGTCTAATAGTTCTTCGAAATCATTAAAATATTTACTGGGAAATAGTCCGAAA
    AGTTATCGAGAATCTAAATATGAAGGTGAGCCTGCACAACATAGTCAGCTTCATGAGAAT
    GAAAATGTTGCTAATGAGTTAATCGACTTCTTATGGAAAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
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    840
    885

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA_RS11460 [old locus tag: SA1990 ]
  • symbol: SA_RS11460
  • description: alpha/beta hydrolase
  • length: 294
  • theoretical pI: 10.1578
  • theoretical MW: 33155.8
  • GRAVY: -0.446259

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
  • TheSEED:
  • PFAM:
    AB_hydrolase (CL0028) DUF915; Alpha/beta hydrolase of unknown function (DUF915) (PF06028; HMM-score: 344.1)
    Abhydrolase_1; alpha/beta hydrolase fold (PF00561; HMM-score: 16.1)
    DUF676; Putative serine esterase (DUF676) (PF05057; HMM-score: 15.7)
    DUF900; Alpha/beta hydrolase of unknown function (DUF900) (PF05990; HMM-score: 12.1)
    Hydrolase_4; Serine aminopeptidase, S33 (PF12146; HMM-score: 11.7)
    no clan definedDAG1; Dystroglycan (Dystrophin-associated glycoprotein 1) (PF05454; HMM-score: 11.4)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helix: 1
  • LocateP:
  • SignalP: Signal peptide length 37 aa
    • Ymax: 0.469
    • Ymax_pos: 37
    • Cmax: 0.564
    • Cmax_pos: 37
    • Smax: 0.618
    • Smax_pos: 3
    • Smean: 0.442
    • D: 0.458
  • predicted transmembrane helices (TMHMM): 1

Accession numbers[edit source | edit]

  • GI:
  • RefSeq: WP_001792547 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MGVKSVKKIFVIITTLLAVAIIIGSIITVVFSQRQAQTFKIQQQQFVKKPIPTLFLHGFGGSANSEKFMVKQAEKRGVTKDIITAYVSKDGAVTFKGKLRKDAVNPIVKIELENNRQGYLDKNAAWFKNVLTKLQSEYNFDKFNFVGHSMGNLTFAQYMMTYGNDKSLPQLNKQVNIAGTFNGVLNMNEDVNEITVDKDGKPSRMNQPYQQLRVLKDIYKGKGIEVLNIYGDLKDGTHSDGRVSNSSSKSLKYLLGNSPKSYRESKYEGEPAQHSQLHENENVANELIDFLWKK

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SA_RS11460 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]