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NCBI: 02-MAR-2017

⊟Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS13075 [old locus tag: SA2279 ]
  • pan locus tag?: SAUPAN006091000
  • symbol: SA_RS13075
  • pan gene symbol?: pgcA
  • synonym:
  • product: phosphoglucomutase

⊟Genome View[edit source | edit]

⊟Gene[edit source | edit]

⊟General[edit source | edit]

  • type: CDS
  • locus tag: SA_RS13075 [old locus tag: SA2279 ]
  • symbol: SA_RS13075
  • product: phosphoglucomutase
  • replicon: chromosome
  • strand: +
  • coordinates: 2554995..2556803
  • length: 1809
  • essential: unknown

⊟Accession numbers[edit source | edit]

  • Location: NC_002745 (2554995..2556803) NCBI
  • MicrobesOnline:

⊟Phenotype[edit source | edit]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    ATGCATTTTCATACACATCTATTATATAATACTTGTGAAAAGTATTGTCTTGGGGCTGTG
    TTTTTTTACTTTTGGGGCGTATTTCTTTATAATTCATTACATAAATGTAAGGGCTTTAGT
    TTTCATGTTTTATTAAGTCTAACTGAGATTTTGAAAGGATGTTTAGCAACAATGGATAAA
    GAATTATGGATAGAAAGAGCTAATGATAGTTTAGTTAAACATTTTTATGAGCAGCAATCT
    GACATTGAACAGCGAGAAGGTTTTGAAAGTAAATTAACATTTGGTACTGCGGGTATACGC
    GGAAAATTCGGTCTTGGTGAAGGTCGACTTAATAAGTTTACTATTGAAAAATTGGCATTA
    GGTTTAGCGCGTTATTTAAATGCCCAAACAAACAGTCCAACAATAGTCATTCATTATGAT
    ATTAGACATCTTTCAACTGAATTCGCCCAAATTATTGCTAATGTATTAGCAAACCATCAA
    ATAACAGTTTATTTACCTGATACATATAAAACGACACCGGAATTATCGTTCGCGGTTCGC
    AATCTTAATACTACTGCCGGCATTATGATTACAGCAAGTCATAATCCGAAAGACTATAAC
    GGCATTAAAGTATATGGTTCTGATGGCGCGCAATTATCGACTGATGCATCTGAGCTTGCA
    AGTCGTTATATCGAAGAAGTTGGCGATCCATTACAGATTGATATACCTATTTCAAAACAA
    AATACATCTTATATCAAACCTTTTCCGAAATCTGTAACTGATGACTATATGAAACACATT
    CAAAATATGATTGGCTATATTCCTAAATCTGATTTACAAGTTGTGTTCACTAGTTTGCAT
    GGTACAAGTGTTCCAATTGTACCTGAGTTATTAAAATCTTTGAATTTCAATCAATTTAAT
    CTTGTAGATGCACAATGTAAACCTGATCCGAATTTTAGTTCAGTTCAAAGTGCTAATCCT
    GAAGATCATCGCGCTTTTGATCAAGCAGTCGAACTTGCAAATAAAAGTCATGCAGACTTA
    TTAATATCAACTGACCCAGATGCAGATCGACTTGGTATTGCTGAACGTGATGCACATGGT
    CATATCACATATTTTAATGGCAACCAAATTGGTGCGCTGTTACTTAATTATCGTATTCAA
    CAAACGTCTCAATTACGTCACCGCTTAATGATTCAATCTATTGTAAGTAGTGAGTTAACA
    AAGTCATTAGCACGCTATAATAATGTTAAATACAAAGAGGTACTGACGGGCTTTAAATTT
    ATTGCTCAGGAAATAAGACAACTGGATGATCATCAAAATATGATTTTCGCATTTGAAGAG
    AGTTACGGTTTTCTATCAGAGCCTTTTGTACGTGATAAAGATGCCGTACAAATTGTGCCA
    CTCATTATAAAATACGCTTCTGAGTTAAAATTATATGGCAAAACATTGAAAGATGAATTA
    GAACAGATTTATCAAACTGTTGGTAGACATGAGGATACATTATTCTCGCATACGCTAGAA
    GGATTAGAAGGTAAGAAAAAAATTGAATCAATTATGACACATTTCCGTTCAAATCCACCG
    CAAGAGATTCAAGGACTGAAAGTGAAAGCAATTGAAGATTATTTAACTAGCGAGGTTTAT
    CATTTGGATAAAGATACAACGTCACAGATTAATTCTTCTAAATCAAATGTTATTCGTGTC
    TTATTTGACGAAGGATTTATCGCTTTACGTCCTTCTGGTACTGAACCTAAAATTAAATTA
    TATGTGTCGTTAAAATGTCCGGATTTTGATGATGTAGCTCAAAAAATTAATGCGATGATT
    TTTAGCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
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    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1809

⊟Protein[edit source | edit]

⊟General[edit source | edit]

  • locus tag: SA_RS13075 [old locus tag: SA2279 ]
  • symbol: SA_RS13075
  • description: phosphoglucomutase
  • length: 602
  • theoretical pI: 6.58718
  • theoretical MW: 68329.3
  • GRAVY: -0.277076

⊟Function[edit source | edit]

  • reaction:
    EC 5.4.2.2?  ExPASy
    Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)Alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate
  • TIGRFAM:
    MetabolismCentral intermediary metabolismAmino sugarsphosphoglucosamine mutase (TIGR03990; EC 5.4.2.10; HMM-score: 171.5)
    Cell structureCell envelopeBiosynthesis and degradation of murein sacculus and peptidoglycanphosphoglucosamine mutase (TIGR01455; EC 5.4.2.10; HMM-score: 98)
    MetabolismCentral intermediary metabolismAmino sugarsphosphoglucosamine mutase (TIGR01455; EC 5.4.2.10; HMM-score: 98)
    MetabolismEnergy metabolismSugarsphosphoglucomutase, alpha-D-glucose phosphate-specific (TIGR01132; EC 5.4.2.2; HMM-score: 74.5)
  • TheSEED:
  • PFAM:
    no clan definedPGM_PMM_I; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain I (PF02878; HMM-score: 142.1)
    PGM_PMM_II; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain II (PF02879; HMM-score: 92.3)
    PGM_PMM_III; Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III (PF02880; HMM-score: 57)
    PGM_PMM_IV; Phosphoglucomutase/phosphomannomutase, C-terminal domain (PF00408; HMM-score: 31.8)
    Peptidase_MH (CL0035) Amidase_3; N-acetylmuramoyl-L-alanine amidase (PF01520; HMM-score: 12.7)
    no clan definedPPP4R2; PPP4R2 (PF09184; HMM-score: 12.4)

⊟Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors: Mg2+
  • effectors:
  • protein partners:

⊟Localization[edit source | edit]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.123
    • Ymax_pos: 56
    • Cmax: 0.118
    • Cmax_pos: 41
    • Smax: 0.219
    • Smax_pos: 43
    • Smean: 0.102
    • D: 0.115
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit source | edit]

  • GI:
  • RefSeq: WP_001835549 NCBI
  • UniProt:

⊟Protein sequence[edit source | edit]

  • MHFHTHLLYNTCEKYCLGAVFFYFWGVFLYNSLHKCKGFSFHVLLSLTEILKGCLATMDKELWIERANDSLVKHFYEQQSDIEQREGFESKLTFGTAGIRGKFGLGEGRLNKFTIEKLALGLARYLNAQTNSPTIVIHYDIRHLSTEFAQIIANVLANHQITVYLPDTYKTTPELSFAVRNLNTTAGIMITASHNPKDYNGIKVYGSDGAQLSTDASELASRYIEEVGDPLQIDIPISKQNTSYIKPFPKSVTDDYMKHIQNMIGYIPKSDLQVVFTSLHGTSVPIVPELLKSLNFNQFNLVDAQCKPDPNFSSVQSANPEDHRAFDQAVELANKSHADLLISTDPDADRLGIAERDAHGHITYFNGNQIGALLLNYRIQQTSQLRHRLMIQSIVSSELTKSLARYNNVKYKEVLTGFKFIAQEIRQLDDHQNMIFAFEESYGFLSEPFVRDKDAVQIVPLIIKYASELKLYGKTLKDELEQIYQTVGRHEDTLFSHTLEGLEGKKKIESIMTHFRSNPPQEIQGLKVKAIEDYLTSEVYHLDKDTTSQINSSKSNVIRVLFDEGFIALRPSGTEPKIKLYVSLKCPDFDDVAQKINAMIFS

⊟Experimental data[edit source | edit]

  • experimentally validated: no data available

⊟Expression & Regulation[edit source | edit]

⊟Operon[edit source | edit]

  • SA_RS13075 no polycistronic organisation predicted

⊟Regulation[edit source | edit]

  • sigma factor:
  • regulator:

⊟Transcription pattern[edit source | edit]

⊟Protein synthesis (provided by Aureolib)[edit source | edit]

⊟Protein stability[edit source | edit]

  • half-life: no data available

⊟Biological Material[edit source | edit]

⊟Mutants[edit source | edit]

⊟Expression vector[edit source | edit]

⊟lacZ fusion[edit source | edit]

⊟GFP fusion[edit source | edit]

⊟two-hybrid system[edit source | edit]

⊟FLAG-tag construct[edit source | edit]

⊟Antibody[edit source | edit]

⊟Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

⊟Literature[edit source | edit]

⊟References[edit source | edit]

⊟Relevant publications[edit source | edit]

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