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NCBI: 02-MAR-2017

Summary[edit source | edit]

  • organism: Staphylococcus aureus N315
  • locus tag: SA_RS13395 [old locus tag: SA2337 ]
  • pan locus tag?: SAUPAN006212000
  • symbol: SA_RS13395
  • pan gene symbol?: feoB
  • synonym:
  • product: ferrous iron transporter B

Genome View[edit source | edit]

Gene[edit source | edit]

General[edit source | edit]

  • type: CDS
  • locus tag: SA_RS13395 [old locus tag: SA2337 ]
  • symbol: SA_RS13395
  • product: ferrous iron transporter B
  • replicon: chromosome
  • strand: -
  • coordinates: 2623372..2625366
  • length: 1995
  • essential: unknown

Accession numbers[edit source | edit]

  • Location: NC_002745 (2623372..2625366) NCBI
  • MicrobesOnline:

Phenotype[edit source | edit]

  • Share your knowledge and add information here. [edit]

DNA sequence[edit source | edit]

  • 1
    61
    121
    181
    241
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    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    ATGGAAAATTATTGTATTTTAGGAAATCCTAATGTTGGTAAAACATCTTTGTTTAACGCT
    TTAACTGGTTCGTATGAATATATAGGCAACTGGAGTGGCGTAACGGTAGAGAAAAAAGTA
    GGGAAACTTAAAGAAAATGTAGGACAATTAATTGATTTACCAGGTACATATGATTTATCG
    CCGATTTCTAAAGATGAAACTGTAGTGACAGACTATTTATTAAACGATTCATTTTCAGGA
    ATCATTAACATTGTTGATGCGAGTCAACTAAAAAGAAATGTGCAATTAACAGTACAATTG
    TTAGAACTTAATCAACCAATATACATCGGATTAAATATGATTGATGTAGCTACAAAGCGC
    GGGATAAAAATCGATTATCATAAATTGATGAAAAAGTTAAAAACACCTATTTTTCCAGTT
    GTGGCACGTACAGGCAAAGGAACAAAATATTTACTTGGCGAAATAAAGCATCTAGGGGAA
    GGGTATCAACCGCATTTTAAAATCAATTATGGTGAGAAGATTGAAGAGACAATTAAAAAT
    ATGTGTCAAATAATAATGACAGAGACATCTCATGATAAGTATCAAGCTAGGTTTATTGCG
    ATTCAATTCTTATTAAATAACATGCAAATTGCAAACGAACTTAATTCAGAGGTTGTAAAT
    AAATTGTCGAGTTTACGTGATCAAGTTGCTGAACAAGTAGGGGCTGTATCTGTTCGTCGA
    GAGATGGAGCGTATACGCAATCATTATATTGAGACGTTATTGCAAGACGTGGTAACGTAT
    CCAGATGAAGATAAGCAATATTTCAGCTCTAGAATAGACAAGATATTAACACATAAATAT
    ATAGGGATGCCTATCTTTCTAGCAATTATGTGGTTGATCTTTCAAACTACATTTACATGG
    ATTGGCACACCTTTGTCGGATCAACTCGATGCATTTATAGGTGGTACATTTACAGATAGT
    GTGAAGACGATTATGAATTATCTAGGGGTTATACCATTTTTACAAGATTTAATTACAGAT
    GGCATTATTGCTGGTGTAGGATCAGTATTAGTCTTTGTACCACAAATTGTTGTGCTCTTT
    TTCTTTATATCTTTATTAGAAGATTCAGGTTATATGGCACGTATTGCGGTTTTAATGGAT
    CGTATTATGGAATCGTTCGGTTTAAGCGGGAAGTCTTTTATACCAATGATTATCGGATTT
    GGTTGTAATGTACCGAGTATTATGGCTGCGCGCAGTATTGAAAATGAAAAAGAGCGTTTA
    ACAACGATATTAATTGCACCATTCATGTCATGCTCTGCTAGACTGCCAGTGTATGCGTTG
    TTCGTAGGTATCTTTTTCAAAGAGAATCAATCTTTAGTAGTATTAAGCCTGTATGTTTTA
    GGTATTATTATGGCATTTTTAGTCAGTACAGTACTTACTAAGACGATTTTAAAAAATGAT
    AATGCAATCTTTATTGTGGAATTGCCAACATACCGTGTGCCTTCCATTAAAACGTTGTGG
    CGTAGTACTTGGGAAAAGGCTAAGGGCTTTGTTCGTAAAGCAGGTACATTTATTTTTGGC
    GGCTCAGTAGTCATTTGGCTATTAAGTTATGTAGGACCACATGGTATCAATGTGAATATC
    AATCAAAGTTTTTTACATATGGTTGGTAGTTTCTTTGGTATGTTAGTGCAACCGCTCGGA
    TTTGGAACATGGCAAGCAGGTGCTACGTTAGTGCCAGGATTTTTAGCAAAAGAAGTTATC
    GTAAGTTCGATGGCGATTATCTATTCATCAGGTGATGCAGGCCTTGTTAATGTGATTCAA
    AATCAATTCACACCGCTATCTGCGTATGCATTTATGATATTTATACTATTGTATATTCCT
    TGTGTTTCTACAGTGGCAGCAATCCGTAAAGAGACTTATTCATGGAAATGGACGGCACTT
    GCAGTTGCCTATCCTCTAGTCACTGCATATGTCTTAACATTCATTTTTTATCAAGTCGGA
    CATTTATTTGTTTAA
    60
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    840
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    1260
    1320
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    1560
    1620
    1680
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    1860
    1920
    1980
    1995

Protein[edit source | edit]

General[edit source | edit]

  • locus tag: SA_RS13395 [old locus tag: SA2337 ]
  • symbol: SA_RS13395
  • description: ferrous iron transporter B
  • length: 664
  • theoretical pI: 8.54816
  • theoretical MW: 74352.8
  • GRAVY: 0.370783

Function[edit source | edit]

  • reaction:
  • TIGRFAM:
    MetabolismTransport and binding proteinsCations and iron carrying compoundsferrous iron transport protein B (TIGR00437; HMM-score: 624.2)
    Unknown functionGeneralsmall GTP-binding protein domain (TIGR00231; HMM-score: 42)
    Genetic information processingProtein synthesisOtherribosome-associated GTPase EngA (TIGR03594; HMM-score: 34.9)
    Genetic information processingProtein synthesisOtherribosome biogenesis GTP-binding protein YlqF (TIGR03596; HMM-score: 27.3)
    Genetic information processingProtein synthesisOtherribosome biogenesis GTP-binding protein YsxC (TIGR03598; HMM-score: 23.3)
    Genetic information processingProtein synthesisOtherGTP-binding protein Era (TIGR00436; HMM-score: 20.6)
    Genetic information processingProtein fateProtein modification and repair[FeFe] hydrogenase H-cluster maturation GTPase HydF (TIGR03918; HMM-score: 20.4)
    Genetic information processingProtein synthesisOtherObg family GTPase CgtA (TIGR02729; HMM-score: 17.6)
    Unknown functionGeneralGTP-binding protein YchF (TIGR00092; HMM-score: 15.4)
    Unknown functionGeneralGTP-binding protein HflX (TIGR03156; HMM-score: 11.4)
    Genetic information processingProtein synthesistRNA and rRNA base modificationtRNA modification GTPase TrmE (TIGR00450; EC 3.6.-.-; HMM-score: 10.4)
  • TheSEED:
  • PFAM:
    P-loop_NTPase (CL0023) FeoB_N; Ferrous iron transport protein B (PF02421; HMM-score: 190.7)
    no clan definedGate; Nucleoside recognition (PF07670; HMM-score: 152.2)
    FeoB_C; Ferrous iron transport protein B C terminus (PF07664; HMM-score: 67.9)
    P-loop_NTPase (CL0023) MMR_HSR1; 50S ribosome-binding GTPase (PF01926; HMM-score: 56)
    SRPRB; Signal recognition particle receptor beta subunit (PF09439; HMM-score: 23.1)
    ATP_bind_1; Conserved hypothetical ATP binding protein (PF03029; HMM-score: 13.4)
    Peptidase_CA (CL0125) Transglut_core2; Transglutaminase-like superfamily (PF13369; HMM-score: 11.3)

Structure, modifications & interactions[edit source | edit]

  • domains:
  • modifications:
  • cofactors:
  • effectors:
  • protein partners:

Localization[edit source | edit]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 9
  • LocateP:
  • SignalP: no predicted signal peptide
    • Ymax: 0.131
    • Ymax_pos: 11
    • Cmax: 0.112
    • Cmax_pos: 35
    • Smax: 0.24
    • Smax_pos: 7
    • Smean: 0.181
    • D: 0.15
  • predicted transmembrane helices (TMHMM): 10

Accession numbers[edit source | edit]

  • GI: 446355060 NCBI
  • RefSeq: WP_000432915 NCBI
  • UniProt:

Protein sequence[edit source | edit]

  • MENYCILGNPNVGKTSLFNALTGSYEYIGNWSGVTVEKKVGKLKENVGQLIDLPGTYDLSPISKDETVVTDYLLNDSFSGIINIVDASQLKRNVQLTVQLLELNQPIYIGLNMIDVATKRGIKIDYHKLMKKLKTPIFPVVARTGKGTKYLLGEIKHLGEGYQPHFKINYGEKIEETIKNMCQIIMTETSHDKYQARFIAIQFLLNNMQIANELNSEVVNKLSSLRDQVAEQVGAVSVRREMERIRNHYIETLLQDVVTYPDEDKQYFSSRIDKILTHKYIGMPIFLAIMWLIFQTTFTWIGTPLSDQLDAFIGGTFTDSVKTIMNYLGVIPFLQDLITDGIIAGVGSVLVFVPQIVVLFFFISLLEDSGYMARIAVLMDRIMESFGLSGKSFIPMIIGFGCNVPSIMAARSIENEKERLTTILIAPFMSCSARLPVYALFVGIFFKENQSLVVLSLYVLGIIMAFLVSTVLTKTILKNDNAIFIVELPTYRVPSIKTLWRSTWEKAKGFVRKAGTFIFGGSVVIWLLSYVGPHGINVNINQSFLHMVGSFFGMLVQPLGFGTWQAGATLVPGFLAKEVIVSSMAIIYSSGDAGLVNVIQNQFTPLSAYAFMIFILLYIPCVSTVAAIRKETYSWKWTALAVAYPLVTAYVLTFIFYQVGHLFV

Experimental data[edit source | edit]

  • experimentally validated: no data available

Expression & Regulation[edit source | edit]

Operon[edit source | edit]

  • SA_RS13395 no polycistronic organisation predicted

Regulation[edit source | edit]

  • sigma factor:
  • regulator:

Transcription pattern[edit source | edit]

Protein synthesis (provided by Aureolib)[edit source | edit]

Protein stability[edit source | edit]

  • half-life: no data available

Biological Material[edit source | edit]

Mutants[edit source | edit]

Expression vector[edit source | edit]

lacZ fusion[edit source | edit]

GFP fusion[edit source | edit]

two-hybrid system[edit source | edit]

FLAG-tag construct[edit source | edit]

Antibody[edit source | edit]

Other Information[edit source | edit]

You are kindly invited to share additional interesting facts.

Literature[edit source | edit]

References[edit source | edit]

Relevant publications[edit source | edit]