PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 01-DEC-2025

⊟Summary

• organism: Staphylococcus aureus JSNZ
• locus tag: EGJ38_001144 [new locus tag: EGJ38_RS05715 ]
• pan locus tag^?: SAUPAN003442000
• symbol: EGJ38_001144
• pan gene symbol^?: —
• synonym:
• alternate name: JSNZ_001144
• product: YjjG family noncanonical pyrimidine nucleotidase

⊟Additional information (user-provided)

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: EGJ38_001144 [new locus tag: EGJ38_RS05715 ]
• symbol: EGJ38_001144
• product: YjjG family noncanonical pyrimidine nucleotidase
• replicon: chromosome
• strand: +
• coordinates: 1142965..1143660
• length: 696
• essential: unknown other strains

⊟Accession numbers

• Gene ID:
• RefSeq: MGT2423110 NCBI
• BioCyc:
• MicrobesOnline:

⊟Phenotype

⊟Additional information (user-provided)

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  
  ATGGGGAAATTGGGATATAAAAATATTTTGATAGACTTTGATGATACAATTGTTGATTTT
  TATGATGCAGAAGAATGGGCGTTTCACTATATGGCGAATGTTTTTAATCATAAAGCAACA
  AAGGATGATTTTTTAACATTTAAAAAAATCAATCACCAACATTGGGAAGCTTTTCAACAA
  AATAAATTAACGAAGTCTGAAGTATTATCAGAACGATTTGTGAATTACTTCAAACATCAT
  CAAATGGAAGTTGATGGGCATCGTGCAGATGTGTTATTTAGAAATGGATTAGCAGAAGCT
  AAAGTTAAATACTTTGATCAAACATTAGAAACAATTGTCGAATTATCGAAAAGACATGAT
  TTATATATTGTTACTAATGGTGTAACCGAAACGCAAAAGAGAAGGTTAAATCAGACGCCG
  TTGCATAAATATATTAAAAAGATATTTATATCTGAGGAAACAGGATATCAAAAACCTAAT
  CCGGAATTTTTTAATTATGTTTTTAATGATATTGGTGAGGATGAAAGACAGCACTCGATT
  ATAGTTGGAGATTCTTTAACATCTGACATTCTAGGTGGAATCAATGCGGGTATAGCTACT
  TGCTGGTTTAATTTTAGAGGATTTGATCATAATCCAGGAATTATACCTGATTATGAAATT
  AATTCATGGAAACAACTAAATGATATTGTACGTTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  696
  

⊟Protein

⊟General

• locus tag: EGJ38_001144 [new locus tag: EGJ38_RS05715 ]
• symbol: EGJ38_001144
• description: YjjG family noncanonical pyrimidine nucleotidase
• length: 231
• theoretical pI: 6.28512
• theoretical MW: 27205.4
• GRAVY: -0.5671

⊟Function

• reaction:
  EC 3.1.3.5?  ExPASy
  5'-nucleotidase A 5'-ribonucleotide + H₂O = a ribonucleoside + phosphate
• TIGRFAM:
  noncanonical pyrimidine nucleotidase, YjjG family (TIGR02254; EC 3.1.3.5; HMM-score: 200.1)
  and 17 more
  HAD hydrolase, TIGR02253 family (TIGR02253; HMM-score: 94.7)
  Unknown function Enzymes of unknown specificity HAD hydrolase, family IA, variant 1 (TIGR01549; HMM-score: 54.5)
  haloacid dehalogenase, type II (TIGR01428; EC 3.8.1.2; HMM-score: 41)
  HAD hydrolase, REG-2-like, family IA (TIGR02252; HMM-score: 41)
  Unknown function Enzymes of unknown specificity HAD hydrolase, family IIA (TIGR01460; HMM-score: 37.8)
  Unknown function Enzymes of unknown specificity HAD hydrolase, family IIIA (TIGR01662; HMM-score: 33.7)
  HAD hydrolase, TIGR01459 family (TIGR01459; HMM-score: 33.2)
  Unknown function Enzymes of unknown specificity HAD hydrolase, family IA, variant 3 (TIGR01509; HMM-score: 30.3)
  HAD phosphatase, family IIIA (TIGR01668; EC 3.1.3.-; HMM-score: 26.9)
  Metabolism Energy metabolism Sugars phosphoglycolate phosphatase, bacterial (TIGR01449; EC 3.1.3.18; HMM-score: 22.9)
  epoxide hydrolase N-terminal domain-like phosphatase (TIGR02247; HMM-score: 22.4)
  histidinol-phosphate phosphatase domain (TIGR01656; HMM-score: 21.2)
  beta-phosphoglucomutase family hydrolase (TIGR02009; HMM-score: 19.7)
  Unknown function Enzymes of unknown specificity HAD hydrolase, TIGR01457 family (TIGR01457; HMM-score: 19.5)
  Unknown function Enzymes of unknown specificity HAD hydrolase, TIGR01458 family (TIGR01458; HMM-score: 13.8)
  Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides beta-phosphoglucomutase (TIGR01990; EC 5.4.2.6; HMM-score: 13.8)
  HAD hydrolase, family IA, variant 2 (TIGR01493; HMM-score: 12.9)
• TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
• PFAM:
  HAD (CL0137) HAD_2; haloacid dehalogenase-like hydrolase (PF13419; HMM-score: 74.3)
  and 3 more
  Hydrolase; haloacid dehalogenase-like hydrolase (PF00702; HMM-score: 57.6)
  Hydrolase_like; HAD-hyrolase-like (PF13242; HMM-score: 38.9)
  STIR (CL0173) TIR_3; Toll/interleukin-1 receptor domain (PF18567; HMM-score: 14.6)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9956
  • Cytoplasmic Membrane Score: 0.0017
  • Cell wall & surface Score: 0.0001
  • Extracellular Score: 0.0026
• LocateP:
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.002276
  • TAT(Tat/SPI): 0.000119
  • LIPO(Sec/SPII): 0.000249
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: MGT2423110 NCBI
• UniProt:

⊟Additional information (user-provided)

⊟Protein sequence

• MGKLGYKNILIDFDDTIVDFYDAEEWAFHYMANVFNHKATKDDFLTFKKINHQHWEAFQQNKLTKSEVLSERFVNYFKHHQMEVDGHRADVLFRNGLAEAKVKYFDQTLETIVELSKRHDLYIVTNGVTETQKRRLNQTPLHKYIKKIFISEETGYQKPNPEFFNYVFNDIGEDERQHSIIVGDSLTSDILGGINAGIATCWFNFRGFDHNPGIIPDYEINSWKQLNDIVR

⊟Experimental data

• experimentally validated: data available for COL, NCTC8325
• protein localization: data available for COL
• quantitative data / protein copy number per cell: data available for COL
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Additional information (user-provided)

⊟Transcription pattern

• S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Additional information (user-provided)

⊟Other information (user-provided)

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications