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NCBI: 22-FEB-2026

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: EGJ38_RS00445 [old locus tag: EGJ38_000088 ]
  • pan locus tag?: SAUPAN000959000
  • symbol: EGJ38_RS00445
  • pan gene symbol?: —
  • synonym:
  • product: bifunctional metallophosphatase/5'-nucleotidase

⊟Additional information (user-provided)[edit | edit source]

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EGJ38_RS00445 [old locus tag: EGJ38_000088 ]
  • symbol: EGJ38_RS00445
  • product: bifunctional metallophosphatase/5'-nucleotidase
  • replicon: chromosome
  • strand: +
  • coordinates: 101602..103137
  • length: 1536
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NZ_CM129921 (101602..103137) NCBI
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGTCAAACATAGCATTTTATGTCGTGAGTGACGTACATGGTTATATTTTCCCAACAGAT
    TTTACGAGTAGAAATCAATATCAGCCTATGGGATTGTTACTAGCGAATCATGTTATAGAA
    CAAGACAGAAGGCAGTATGACCAAAGTTTTAAAATAGATAATGGTGATTTTTTGCAAGGG
    TCACCATTTTGTAATTACTTAATCGCGCATAGCGGCAGTAGTCAGCCTTTAGTTGATTTT
    TATAATCGAATGGCATTCGACTTTGGTACGCTTGGTAATCATGAATTTAATTATGGATTA
    CCATACTTAAAAGACACTTTACGCAGACTCAATTATCCAGTTTTGTGCGCTAATATTTAT
    GAAAATGATAGTACATTGACTGATAACGGTGTGCAGTATTTTCAGGTTGGAGATCAAACG
    GTTGGTGTGATAGGTTTAACGACACAATTTATTCCCCATTGGGAACAACCAGAGCATATT
    CAGTCACTTACGTTTCATAGTGCTTTTGAAACACTTCAACAACACTTACCTGAAATGAAG
    CGACATGCAGATATCATTGTGGTTTGTTACCATGGTGGATTTGAAAAGGATTTAGAAAGT
    GGTACGCCGACCGAAGTGTTAACGGGTGAAAATGAAGGATATGCCATGTTAGAAGCGTTT
    TCTAAAGATATAGATATCTTTATTACGGGTCACCAACATCGACAAATTGCTGAAAGGTTT
    AAGCAAACGGCTGTGATTCAACCTGGTACGAGAGGTACAACTGTAGGCAAAGTTGTCTTG
    AGTACTGATGAATATGAAAATGTATCCGTTGAATCATGTGAATTACTTCCTGTTATAGAT
    GATTCCACATTTACTATTGATGAAGATGACCAACATATACGAAAGCAGTTAGAGGACTGG
    TTAGATTACGAAATTACTACATTGCCATATGATATGACGATTAATCATGCATTTGAGGCA
    CGTGTAGCTCCGCATCCTTTTACTAATTTTATGAATTACGCTTTTTTAGAAAAAAGTGGT
    GCAGATGTTGCATGTACAGCTTTGTTTGATTCTGCTAGTGGTTTCAAGCAAGTCGTGACG
    ATGCGAGATGTTATTAACAATTACCCATTTCCAAATACATTTAAAGTTTTAGCTGTAAGT
    GGTGCCAAACTTAAAGAAGCCATTGAACGATCAGCAGAATATTTTGACGTGAAAAATGAT
    AAAGTAAGTGTAAGCGCAGACTTCCTTGAACCCAAACCACAACACTTTAATTATGATATA
    TATGGTGGCGTAAGTTATACCATTAATGTTGGCAGACCAAAGGGACAACGTGTGAGTAAT
    ATGATGATTCAAGGTCACGCAGTTGATTTAAAGCAGACATATACAATTTGTGTAAATAAT
    TATCGTGCAGTTGGCGGTGGTCAGTATGATATGTATATCGAAGCGCCAGTTGTAAAAGAT
    ATTCAAGTTGAAGGCGCACAATTACTTATTGATTTTTTATCAAATAATAATTTGATGCGT
    ATCCCGCAAGTTGTTGATTTTAAAGTTGAAAAGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1536


⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EGJ38_RS00445 [old locus tag: EGJ38_000088 ]
  • symbol: EGJ38_RS00445
  • description: bifunctional metallophosphatase/5'-nucleotidase
  • length: 511
  • theoretical pI: 4.69503
  • theoretical MW: 57995.7
  • GRAVY: -0.304892

⊟Function[edit | edit source]

  • reaction:
    EC 3.1.3.5?  ExPASy
    5'-nucleotidase A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate
  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Other 2',3'-cyclic-nucleotide 2'-phosphodiesterase (TIGR01390; EC 3.1.4.16; HMM-score: 171.2)
    and 4 more
    thiosulfohydrolase SoxB (TIGR04486; HMM-score: 82.1)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pyridine nucleotides NAD nucleotidase (TIGR01530; EC 3.1.3.5,3.6.1.22; HMM-score: 59)
    Metabolism Transport and binding proteins Other NAD nucleotidase (TIGR01530; EC 3.1.3.5,3.6.1.22; HMM-score: 59)
    Unknown function Enzymes of unknown specificity phosphodiesterase, MJ0936 family (TIGR00040; EC 3.1.-.-; HMM-score: 18.1)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    NadN_C (CL0781) 5_nucleotid_C; 5'-nucleotidase, C-terminal domain (PF02872; HMM-score: 98.6)
    and 3 more
    Calcineurin (CL0163) Metallophos; Calcineurin-like phosphoesterase (PF00149; HMM-score: 32.9)
    Metallophos_2; Calcineurin-like phosphoesterase superfamily domain (PF12850; HMM-score: 16.6)
    PGA_cap; Bacterial capsule synthesis protein PGA_cap (PF09587; HMM-score: 15.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.11
    • Cytoplasmic Membrane Score: 0.02
    • Cellwall Score: 8.97
    • Extracellular Score: 0.9
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9915
    • Cytoplasmic Membrane Score: 0.0026
    • Cell wall & surface Score: 0.0009
    • Extracellular Score: 0.005
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005944
    • TAT(Tat/SPI): 0.000207
    • LIPO(Sec/SPII): 0.001346
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000065049 NCBI
  • UniProt:

⊟Additional information (user-provided)[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSNIAFYVVSDVHGYIFPTDFTSRNQYQPMGLLLANHVIEQDRRQYDQSFKIDNGDFLQGSPFCNYLIAHSGSSQPLVDFYNRMAFDFGTLGNHEFNYGLPYLKDTLRRLNYPVLCANIYENDSTLTDNGVQYFQVGDQTVGVIGLTTQFIPHWEQPEHIQSLTFHSAFETLQQHLPEMKRHADIIVVCYHGGFEKDLESGTPTEVLTGENEGYAMLEAFSKDIDIFITGHQHRQIAERFKQTAVIQPGTRGTTVGKVVLSTDEYENVSVESCELLPVIDDSTFTIDEDDQHIRKQLEDWLDYEITTLPYDMTINHAFEARVAPHPFTNFMNYAFLEKSGADVACTALFDSASGFKQVVTMRDVINNYPFPNTFKVLAVSGAKLKEAIERSAEYFDVKNDKVSVSADFLEPKPQHFNYDIYGGVSYTINVGRPKGQRVSNMMIQGHAVDLKQTYTICVNNYRAVGGGQYDMYIEAPVVKDIQVEGAQLLIDFLSNNNLMRIPQVVDFKVEK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Additional information (user-provided)[edit | edit source]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Additional information (user-provided)[edit | edit source]

⊟Other information (user-provided)[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]


⊟Relevant publications[edit | edit source]

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