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NCBI: 22-FEB-2026
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: EGJ38_RS09940 [old locus tag: EGJ38_001991 ]
- pan locus tag?: SAUPAN005279000
- symbol: agrC
- pan gene symbol?: agrC
- synonym:
- product: quorum-sensing sensor histidine kinase AgrC
⊟Additional information (user-provided)[edit | edit source]
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: EGJ38_RS09940 [old locus tag: EGJ38_001991 ]
- symbol: agrC
- product: quorum-sensing sensor histidine kinase AgrC
- replicon: chromosome
- strand: +
- coordinates: 2004375..2005667
- length: 1293
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Location: NZ_CM129921 (2004375..2005667) NCBI
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
⊟Additional information (user-provided)[edit | edit source]
⊟DNA sequence[edit | edit source]
- 1
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1261GTGGAAGCATTAAATGATTATAATTACGTTTTATTTGTAATTGTTCAAGTTTCATTAATG
TTCTTTATATCTGCATTTATTAGTGGAATAAGATACAAAAAATCAGATTATATATACATT
ATTGGAATAGTGTTATCTTCAGTATATTTCTTTGACAAAATCGGAAATATTTCACTAGTT
GTTATAACAATTTTTATAATAATTTTTCTCTATTTTAAAATTAGACTATATTCTGTATTT
TTAGTAATGGTTACTCAAATCATTTTATATTGTGCAAATTTCGTTTATATCATTATTTTT
TCATACATTATAACAATTTCACACAGCGTGTTTATAGTTCTACCAATCTTTTTGGTAGTG
TATGTATCAATTTCTTATGCACTTGCCTACATTTTAAATAGAATATTAAAAAGGATAAAT
GGTACATACCTTTCTCTTAATAAAAAATTCCTTACTGTTATAACTATTGTTATAGTAATA
ACATTCTCTTTGTTATTTGCATATTCGCAAATTGATGCGAGTGATGCATCAACAATCAAA
CAGTATTCGCTTTTATTCTTGGGAATTATTATATTACTGAGTATCTTAATTTTTATTTAT
TCTCAATTTACTCTTAAAGAAATGAAATATAAACGTAATCAAGAAGAAATTGAAACCTAT
TATGAATACACATTAAAGATTGAAGCAATTAATAATGAAATGCGCAAGTTCCGTCATGAT
TATGTCAATATCTTGACGACTCTTTCAGAATACATTCGTGAAGATGACATGACCGGTCTT
CGAGACTATTTCAATAAAAATATTGTACCTATGAAAGATAATTTACAAATGAATGCTCTT
AAGTTAAATGGTATTGAGAATCTTAAAGTACGTGAGATTAAAGGTCTTCTAACAGCTAAA
ATTTTACGTGCACAAGAAATGAATATACCGATTAGTATAGAAATACCAGATGAAGTAACT
CGCATTAATTTGAATATGATCGATTTAAGTCGCAGTATTGGTATTATTCTTGATAACGCA
ATAGAGGCATCAAGTGAAATTGATGATCCTATCATTCGAGTTGCATTTATTGAAAGCGAA
AATTCAGTAACGTTTATTGTTATGAATAAATGTGCAGATGATATACCACGTATTCATGAA
TTGTTCCAAGAAAGTTTTTCTACTAAAGGTGAAGGTCGTGGTTTAGGTCTATCAACTTTA
AAAGAAATTGCTGATAATGCAGACAATGTCTTATTAGATACAATTATCGAGAATGGTTTC
TTTATTCAAAAGGTTGAAATTATTAACAACTAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: EGJ38_RS09940 [old locus tag: EGJ38_001991 ]
- symbol: AgrC
- description: quorum-sensing sensor histidine kinase AgrC
- length: 430
- theoretical pI: 5.15112
- theoretical MW: 49655.1
- GRAVY: 0.505116
⊟Function[edit | edit source]
- reaction: EC 2.7.13.3? ExPASyHistidine kinase ATP + protein L-histidine = ADP + protein N-phospho-L-histidine
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: His_Kinase_A (CL0025) HATPase_c_5; GHKL domain (PF14501; HMM-score: 88.6)and 4 moreHATPase_c; Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (PF02518; HMM-score: 27.1)GHD (CL0369) Glyco_hydro_30C; Glycosyl hydrolase family 30 beta sandwich domain (PF17189; HMM-score: 14.7)no clan defined SPOB_a; Sensor_kinase_SpoOB-type, alpha-helical domain (PF14689; HMM-score: 14.1)MTR4-like_stalk; Exosome RNA helicase MTR4-like, stalk (PF21408; HMM-score: 10.3)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 6
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0.0003
- Cytoplasmic Membrane Score: 0.9884
- Cell wall & surface Score: 0.0003
- Extracellular Score: 0.011
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.001991
- TAT(Tat/SPI): 0.000139
- LIPO(Sec/SPII): 0.02433
- predicted transmembrane helices (TMHMM): 6
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_206423041 NCBI
- UniProt:
⊟Additional information (user-provided)[edit | edit source]
⊟Protein sequence[edit | edit source]
- MEALNDYNYVLFVIVQVSLMFFISAFISGIRYKKSDYIYIIGIVLSSVYFFDKIGNISLVVITIFIIIFLYFKIRLYSVFLVMVTQIILYCANFVYIIIFSYIITISHSVFIVLPIFLVVYVSISYALAYILNRILKRINGTYLSLNKKFLTVITIVIVITFSLLFAYSQIDASDASTIKQYSLLFLGIIILLSILIFIYSQFTLKEMKYKRNQEEIETYYEYTLKIEAINNEMRKFRHDYVNILTTLSEYIREDDMTGLRDYFNKNIVPMKDNLQMNALKLNGIENLKVREIKGLLTAKILRAQEMNIPISIEIPDEVTRINLNMIDLSRSIGIILDNAIEASSEIDDPIIRVAFIESENSVTFIVMNKCADDIPRIHELFQESFSTKGEGRGLGLSTLKEIADNADNVLLDTIIENGFFIQKVEIINN
⊟Experimental data[edit | edit source]
- experimentally validated: data available for COL, NCTC8325
- protein localization: data available for COL
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator: AgrA, CodY see EGJ38_001991
⊟Additional information (user-provided)[edit | edit source]
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Additional information (user-provided)[edit | edit source]
⊟Other information (user-provided)[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]