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NCBI: 22-FEB-2026
⊟Summary[edit | edit source]
- organism: Staphylococcus aureus JSNZ
- locus tag: EGJ38_RS10665 [old locus tag: EGJ38_002137 ]
- pan locus tag?: SAUPAN005555000
- symbol: sepA
- pan gene symbol?: sepA
- synonym:
- product: multidrug efflux transporter SepA
⊟Additional information (user-provided)[edit | edit source]
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: EGJ38_RS10665 [old locus tag: EGJ38_002137 ]
- symbol: sepA
- product: multidrug efflux transporter SepA
- replicon: chromosome
- strand: -
- coordinates: 2154030..2154503
- length: 474
- essential: unknown other strains
⊟Accession numbers[edit | edit source]
- Location: NZ_CM129921 (2154030..2154503) NCBI
- BioCyc:
- MicrobesOnline:
⊟Phenotype[edit | edit source]
⊟Additional information (user-provided)[edit | edit source]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421ATGATTGTGAATTATCTTAAACATAAGTTTTATAACTTGTTAACTACAATGATTGTTCTC
TTTATTTTTGTACTTTCTGGTGCGATTTTTTTAACATTTCTAGGGTTTGGTTTATATGGA
TTAAGTAGAATACTTATTTATTTTAGGTTGGGTGACTTTACATATAATAGAAGTATGTAC
GATAACCTATTATATTATGGCAGTTATATAATCTTTGGGTACTTCATCATATTTGCAGTC
GAGCATTTAATGGATTATTTTAGAAAAATGTTGCCTGAAAATGCATATTTTAGAGGCGCG
ACTTTTCATTTGATTTCTTACACAGTTGCAACAACGTTATTTTATTTTATTATTCATCTG
AACTATGTGTATATCAATATCGATTTTTGGGTCATCATGGTTATTATAGGGTTCTTATAT
GTTTGTAAGCTTCAATTTTACCCTGAAAGTAAAAATTTAAATAATAGAAAATAG60
120
180
240
300
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420
474
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: EGJ38_RS10665 [old locus tag: EGJ38_002137 ]
- symbol: SepA
- description: multidrug efflux transporter SepA
- length: 157
- theoretical pI: 9.40365
- theoretical MW: 18899.3
- GRAVY: 0.681529
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
- PFAM: no clan defined SepA; Multidrug Resistance efflux pump (PF17080; HMM-score: 138.6)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 4
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0.0002
- Cytoplasmic Membrane Score: 0.9894
- Cell wall & surface Score: 0
- Extracellular Score: 0.0104
- LocateP:
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.002375
- TAT(Tat/SPI): 0.000374
- LIPO(Sec/SPII): 0.032554
- predicted transmembrane helices (TMHMM): 4
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq: WP_000636857 NCBI
- UniProt:
⊟Additional information (user-provided)[edit | edit source]
⊟Protein sequence[edit | edit source]
- MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
⊟Experimental data[edit | edit source]
- experimentally validated:
- protein localization:
- quantitative data / protein copy number per cell:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Additional information (user-provided)[edit | edit source]
⊟Transcription pattern[edit | edit source]
- S.aureus Expression Data Browser: data available for NCTC8325
⊟Protein synthesis (provided by Aureolib)[edit | edit source]
- Aureolib: no data available
⊟Protein stability[edit | edit source]
- half-life: no data available
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Additional information (user-provided)[edit | edit source]
⊟Other information (user-provided)[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]