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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000088
  • pan locus tag?: SAUPAN000959000
  • symbol: JSNZ_000088
  • pan gene symbol?: —
  • synonym:
  • product: bifunctional UDP-sugar hydrolase/5'-nucleotidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000088
  • symbol: JSNZ_000088
  • product: bifunctional UDP-sugar hydrolase/5'-nucleotidase
  • replicon: chromosome
  • strand: +
  • coordinates: 101602..103137
  • length: 1536
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    ATGTCAAACATAGCATTTTATGTCGTGAGTGACGTACATGGTTATATTTTCCCAACAGAT
    TTTACGAGTAGAAATCAATATCAGCCTATGGGATTGTTACTAGCGAATCATGTTATAGAA
    CAAGACAGAAGGCAGTATGACCAAAGTTTTAAAATAGATAATGGTGATTTTTTGCAAGGG
    TCACCATTTTGTAATTACTTAATCGCGCATAGCGGCAGTAGTCAGCCTTTAGTTGATTTT
    TATAATCGAATGGCATTCGACTTTGGTACGCTTGGTAATCATGAATTTAATTATGGATTA
    CCATACTTAAAAGACACTTTACGCAGACTCAATTATCCAGTTTTGTGCGCTAATATTTAT
    GAAAATGATAGTACATTGACTGATAACGGTGTGCAGTATTTTCAGGTTGGAGATCAAACG
    GTTGGTGTGATAGGTTTAACGACACAATTTATTCCCCATTGGGAACAACCAGAGCATATT
    CAGTCACTTACGTTTCATAGTGCTTTTGAAACACTTCAACAACACTTACCTGAAATGAAG
    CGACATGCAGATATCATTGTGGTTTGTTACCATGGTGGATTTGAAAAGGATTTAGAAAGT
    GGTACGCCGACCGAAGTGTTAACGGGTGAAAATGAAGGATATGCCATGTTAGAAGCGTTT
    TCTAAAGATATAGATATCTTTATTACGGGTCACCAACATCGACAAATTGCTGAAAGGTTT
    AAGCAAACGGCTGTGATTCAACCTGGTACGAGAGGTACAACTGTAGGCAAAGTTGTCTTG
    AGTACTGATGAATATGAAAATGTATCCGTTGAATCATGTGAATTACTTCCTGTTATAGAT
    GATTCCACATTTACTATTGATGAAGATGACCAACATATACGAAAGCAGTTAGAGGACTGG
    TTAGATTACGAAATTACTACATTGCCATATGATATGACGATTAATCATGCATTTGAGGCA
    CGTGTAGCTCCGCATCCTTTTACTAATTTTATGAATTACGCTTTTTTAGAAAAAAGTGGT
    GCAGATGTTGCATGTACAGCTTTGTTTGATTCTGCTAGTGGTTTCAAGCAAGTCGTGACG
    ATGCGAGATGTTATTAACAATTACCCATTTCCAAATACATTTAAAGTTTTAGCTGTAAGT
    GGTGCCAAACTTAAAGAAGCCATTGAACGATCAGCAGAATATTTTGACGTGAAAAATGAT
    AAAGTAAGTGTAAGCGCAGACTTCCTTGAACCCAAACCACAACACTTTAATTATGATATA
    TATGGTGGCGTAAGTTATACCATTAATGTTGGCAGACCAAAGGGACAACGTGTGAGTAAT
    ATGATGATTCAAGGTCACGCAGTTGATTTAAAGCAGACATATACAATTTGTGTAAATAAT
    TATCGTGCAGTTGGCGGTGGTCAGTATGATATGTATATCGAAGCGCCAGTTGTAAAAGAT
    ATTCAAGTTGAAGGCGCACAATTACTTATTGATTTTTTATCAAATAATAATTTGATGCGT
    ATCCCGCAAGTTGTTGATTTTAAAGTTGAAAAGTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1536

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000088
  • symbol: JSNZ_000088
  • description: bifunctional UDP-sugar hydrolase/5'-nucleotidase
  • length: 511
  • theoretical pI: 4.69503
  • theoretical MW: 57995.7
  • GRAVY: -0.304892

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Other 2',3'-cyclic-nucleotide 2'-phosphodiesterase (TIGR01390; EC 3.1.4.16; HMM-score: 171.2)
    and 4 more
    thiosulfohydrolase SoxB (TIGR04486; HMM-score: 82.1)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pyridine nucleotides NAD nucleotidase (TIGR01530; EC 3.1.3.5,3.6.1.22; HMM-score: 59)
    Metabolism Transport and binding proteins Other NAD nucleotidase (TIGR01530; EC 3.1.3.5,3.6.1.22; HMM-score: 59)
    Unknown function Enzymes of unknown specificity phosphodiesterase, MJ0936 family (TIGR00040; EC 3.1.-.-; HMM-score: 18.1)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    NadN_C (CL0781) 5_nucleotid_C; 5'-nucleotidase, C-terminal domain (PF02872; HMM-score: 98.6)
    and 3 more
    Calcineurin (CL0163) Metallophos; Calcineurin-like phosphoesterase (PF00149; HMM-score: 32.9)
    Metallophos_2; Calcineurin-like phosphoesterase superfamily domain (PF12850; HMM-score: 16.6)
    PGA_cap; Bacterial capsule synthesis protein PGA_cap (PF09587; HMM-score: 15.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.11
    • Cytoplasmic Membrane Score: 0.02
    • Cellwall Score: 8.97
    • Extracellular Score: 0.9
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9915
    • Cytoplasmic Membrane Score: 0.0026
    • Cell wall & surface Score: 0.0009
    • Extracellular Score: 0.005
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005944
    • TAT(Tat/SPI): 0.000207
    • LIPO(Sec/SPII): 0.001346
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSNIAFYVVSDVHGYIFPTDFTSRNQYQPMGLLLANHVIEQDRRQYDQSFKIDNGDFLQGSPFCNYLIAHSGSSQPLVDFYNRMAFDFGTLGNHEFNYGLPYLKDTLRRLNYPVLCANIYENDSTLTDNGVQYFQVGDQTVGVIGLTTQFIPHWEQPEHIQSLTFHSAFETLQQHLPEMKRHADIIVVCYHGGFEKDLESGTPTEVLTGENEGYAMLEAFSKDIDIFITGHQHRQIAERFKQTAVIQPGTRGTTVGKVVLSTDEYENVSVESCELLPVIDDSTFTIDEDDQHIRKQLEDWLDYEITTLPYDMTINHAFEARVAPHPFTNFMNYAFLEKSGADVACTALFDSASGFKQVVTMRDVINNYPFPNTFKVLAVSGAKLKEAIERSAEYFDVKNDKVSVSADFLEPKPQHFNYDIYGGVSYTINVGRPKGQRVSNMMIQGHAVDLKQTYTICVNNYRAVGGGQYDMYIEAPVVKDIQVEGAQLLIDFLSNNNLMRIPQVVDFKVEK

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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