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PangenomeCOLN315NCTC8325NewmanUSA300_FPR3757JSNZ04-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000090
  • pan locus tag?: SAUPAN000963000
  • symbol: JSNZ_000090
  • pan gene symbol?: —
  • synonym:
  • product: helix-turn-helix domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000090
  • symbol: JSNZ_000090
  • product: helix-turn-helix domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 104067..105242
  • length: 1176
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGTTTATTGGCAAGAATTTAGAATACGTGAGAAAGCTTAATGCTCTAAGTAGAAAAGAA
    TTATCAGAAAAAATAAATGTGAGTGAACAAGCAATTTGGCAATATGAAACAAAAAATATG
    ATGCCAGAAATTAGTAAAATTTATGATATGACATCTATTTTTAATGTTAAATCTAGCTAC
    TTTATTAGCGAGCAGCCCGAAGAGCTCCTAATAAATTCTGTCGATAAACATAGTATAGCT
    TTTAGAGCAAAAAATTATAAAGTATCTACGAAACTATTAAATAAGCAATATTATCAAGCA
    ATGTATTTATCTAATTTAACTAGCTACTTATTTTCTTTTGTAACGATACCGGATAATATT
    ATTTTATCTTTAATAAATAATTTAGATGAATTGTTGAATGGCAATTTAGAATCACTAAAT
    AAAAAAGAAAGCATAAAAGAAATTGCTAAAGTTGTGAGGGCTAAAATTCTTCAAGATGAA
    AGCAACGAAGCACTATTATTTATGCTTGAAAAAGCGGGTATAGTTATATACGAAAAGCGA
    ATTAATGATAGCATAGACGCATATAGTTTTTGGAGTAAAGATCAGACACCTTTTATTATA
    CTGGGTACAAATAAGGGGGTAGCAGTTAGAAGGAATTTTGATCTTGCACATGAGCTGGGA
    CATCTCGTTCTACATCGTCATATTCAATTCGACTTATTATCTCCTGAAGAATATAAGACA
    ATTGAACATGAGGCAGATATTTTCGCCTCTGAATTTTTACTACCTGAAGAAGCGTTTAAA
    AAAGACTTTGATCAAATGACCAAAAAATCAAATCCTGATTATTTAGCTGTATTGAAAGAA
    AAATGGTATGTTTCTATACAAGCAATTGCAATGAGAGCGTATTATCTAGGCCTAATGTCT
    AGTACTCAGTACAGATATTTTTGGGCATCATTAAATAAAAAAGGCTATAAAAGTAAAGAG
    CCTTTAGACGACGTGATTGAAATGTCACGTCCTGTCAAAATGAATAGTTTATTAAAGTTG
    TATTTTGATAGAAATATACTGACACCACAAAAATTATTGAATTATTTAAAAGTCGATGAA
    ACATTTTTGAATCATCTAGCAGGTATTAATTTAAAACTCTTTAAGGATTATGTTAATGAA
    AATAGAGAATATAATATAACGAATCTATATAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1176

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000090
  • symbol: JSNZ_000090
  • description: helix-turn-helix domain-containing protein
  • length: 391
  • theoretical pI: 8.77161
  • theoretical MW: 45885.6
  • GRAVY: -0.332737

⊟Function[edit | edit source]

  • TIGRFAM:
    putative zinc finger/helix-turn-helix protein, YgiT family (TIGR03830; HMM-score: 14.2)
    Hypothetical proteins Conserved TIGR00270 family protein (TIGR00270; HMM-score: 13.6)
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, y4mF family (TIGR03070; HMM-score: 13.5)
  • TheSEED: data available for N315
  • PFAM:
    Peptidase_MA (CL0126) Peptidase_M78; IrrE N-terminal-like domain (PF06114; HMM-score: 73.3)
    and 5 more
    HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 26)
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 21.2)
    HTH_11; HTH domain (PF08279; HMM-score: 18.6)
    no clan defined CANIN; Coiled-coil and Nse Interacting (CANIN) domain (PF14816; HMM-score: 16.4)
    HTH (CL0123) HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 13.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7093
    • Cytoplasmic Membrane Score: 0.2111
    • Cell wall & surface Score: 0.0008
    • Extracellular Score: 0.0788
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002578
    • TAT(Tat/SPI): 0.000156
    • LIPO(Sec/SPII): 0.000534
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFIGKNLEYVRKLNALSRKELSEKINVSEQAIWQYETKNMMPEISKIYDMTSIFNVKSSYFISEQPEELLINSVDKHSIAFRAKNYKVSTKLLNKQYYQAMYLSNLTSYLFSFVTIPDNIILSLINNLDELLNGNLESLNKKESIKEIAKVVRAKILQDESNEALLFMLEKAGIVIYEKRINDSIDAYSFWSKDQTPFIILGTNKGVAVRRNFDLAHELGHLVLHRHIQFDLLSPEEYKTIEHEADIFASEFLLPEEAFKKDFDQMTKKSNPDYLAVLKEKWYVSIQAIAMRAYYLGLMSSTQYRYFWASLNKKGYKSKEPLDDVIEMSRPVKMNSLLKLYFDRNILTPQKLLNYLKVDETFLNHLAGINLKLFKDYVNENREYNITNLYK

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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