PangenomeCOLN315NCTC8325NewmanUSA300_FPR375704-0298108BA0217611819-97685071193ECT-R 2ED133ED98HO 5096 0412JH1JH9JKD6008JKD6159LGA251M013MRSA252MSHR1132MSSA476MW2Mu3Mu50RF122ST398T0131TCH60TW20USA300_TCH1516VC40

NCBI: 26-AUG-2013

⊟Summary

• organism: Staphylococcus aureus N315
• locus tag: SA0142 [new locus tag: SA_RS00880 ]
• pan locus tag^?: SAUPAN000963000
• symbol: SA0142
• pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SA0142 [new locus tag: SA_RS00880 ]
• symbol: SA0142
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 162897..164072
• length: 1176
• essential: no DEG

⊟Accession numbers

• Gene ID: 1122917 NCBI
• RefSeq: NP_373384 NCBI
• BioCyc: see SA_RS00880
• MicrobesOnline: 102410 MicrobesOnline

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
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  1141
  
  ATGTTTATTGGCAAGAATTTAGAATACGTGAGAAAGCTTAATGCTCTAAGTAGAAAAGAA
  TTATCAGAAAAAATAAATGTGAGTGAACAAGCAATTTGGCAATATGAAACAAAAAATATG
  ATGCCAGAAATTAGTAAAATTTATGATATGACATCTATTTTTAATGTTAAATCTAGCTAC
  TTTATTAGCGAGCAGCCCGAAGAGCTCCTAATAAATTCTGTCGATAAACATAGTATAGCT
  TTTAGAGCAAAAAATTATAAAGTATCTACGAAACTATTAAATAAGCAATATTATCAAGCA
  ATGTATTTATCTAATTTAACTAGCTACTTATTTTCTTTTGTAACGATACCGGATAATATT
  ATTTTATCTTTAATAAATAATTTAGATGAATTGTTGAATGGCAATTTAGAATCACTAAAT
  AAAAAAGAAAGCATAAAAGAAATTGCTAAAGTTGTGAGGGCTAAAATTCTTCAAGATGAA
  AGCAACGAAGCACTATTATTTATGCTTGAAAAAGCGGGTATAGTTATATACGAAAAGCGA
  ATTAATGATAGCATAGACGCATATAGTTTTTGGAGTAAAGATCAGACACCTTTTATTATA
  CTGGGTACAAATAGGGGGGTAGCAGTTAGAAGGAATTTTGATCTTGCACATGAGCTGGGA
  CATCTCGTTCTACATCGTCATATTCAATTCGACTTATTATCTCCTGAAGAATATAAGACA
  ATTGAACATGAGGCAGATATTTTCGCCTCTGAATTTTTACTACCTGAAGAAGCGTTTAAA
  AAAGACTTTGATCAAATGACCAAAAAATCAAATCCTGATTATTTAGCTGTATTGAAAGAA
  AAATGGTATGTTTCTATACAAGCAATTGCAATGAGAGCTTATTATCTAGGCCTAATGTCT
  AGTACTCAGTACAGATATTTTTGGGCATCATTAAATAAAAAAGGCTATAAAAGTAAAGAG
  CCTTTAGACGACGTGATTGAAATGTCACGTCCTGTCAAAATGAATAGTTTATTAAAGTTG
  TATTTTGATAGAAATATACTGACACCACAAAAATTATTGAATTATTTAAAAGTCGATGAA
  ACATTTTTGAATCATCTAGCAGGTATTAATTTAAAACTCTTTAAGGATTATGTTAATGAA
  AATAGAGAATATAATATAACGAATCTATATAAATAA
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  1176
  

⊟Protein

⊟General

• locus tag: SA0142 [new locus tag: SA_RS00880 ]
• symbol: SA0142
• description: hypothetical protein
• length: 391
• theoretical pI: 8.77399
• theoretical MW: 45913.6
• GRAVY: -0.334271

⊟Function

• TIGRFAM:
  putative zinc finger/helix-turn-helix protein, YgiT family (TIGR03830; HMM-score: 14.2)
  Hypothetical proteins Conserved TIGR00270 family protein (TIGR00270; HMM-score: 13.6)
  Signal transduction Regulatory functions DNA interactions transcriptional regulator, y4mF family (TIGR03070; HMM-score: 13.5)
• TheSEED  :
  • Zn peptidase with DNA binding
• PFAM:
  Peptidase_MA (CL0126) Peptidase_M78; IrrE N-terminal-like domain (PF06114; HMM-score: 68.3)
  and 7 more
  HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 28.2)
  HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 20.8)
  HTH_11; HTH domain (PF08279; HMM-score: 18.8)
  Peptidase_MA (CL0126) Peptidase_U49; Peptidase U49 (PF10463; HMM-score: 16.8)
  no clan defined FAM178; Family of unknown function, FAM178 (PF14816; HMM-score: 14.4)
  Sigma70_r1_1; Sigma-70 factor, region 1.1 (PF03979; HMM-score: 13.3)
  HTH (CL0123) HTH_24; Winged helix-turn-helix DNA-binding (PF13412; HMM-score: 12.7)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helices: 0
• LocateP: Intracellular
  • Prediction by SwissProt Classification: Cytoplasmic
  • Pathway Prediction: No pathway
  • Intracellular possibility: 1
  • Signal peptide possibility: -1
  • N-terminally Anchored Score: 1
  • Predicted Cleavage Site: No CleavageSite
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.002578
  • TAT(Tat/SPI): 0.000156
  • LIPO(Sec/SPII): 0.000534
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI: 15925851 NCBI
• RefSeq: NP_373384 NCBI
• UniProt: A0A0H3JNB2 UniProt

⊟Protein sequence

• MFIGKNLEYVRKLNALSRKELSEKINVSEQAIWQYETKNMMPEISKIYDMTSIFNVKSSYFISEQPEELLINSVDKHSIAFRAKNYKVSTKLLNKQYYQAMYLSNLTSYLFSFVTIPDNIILSLINNLDELLNGNLESLNKKESIKEIAKVVRAKILQDESNEALLFMLEKAGIVIYEKRINDSIDAYSFWSKDQTPFIILGTNRGVAVRRNFDLAHELGHLVLHRHIQFDLLSPEEYKTIEHEADIFASEFLLPEEAFKKDFDQMTKKSNPDYLAVLKEKWYVSIQAIAMRAYYLGLMSSTQYRYFWASLNKKGYKSKEPLDDVIEMSRPVKMNSLLKLYFDRNILTPQKLLNYLKVDETFLNHLAGINLKLFKDYVNENREYNITNLYK

⊟Experimental data

• experimentally validated:
• protein localization:
• quantitative data / protein copy number per cell:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: SA0141 > SA0142

⊟Regulation

• regulator:

⊟Transcription pattern

• S.aureus Expression Data Browser: no data available

⊟Protein synthesis (provided by Aureolib)

• Aureolib: no data available

⊟Protein stability

• half-life: no data available

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications