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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000385
  • pan locus tag?: SAUPAN002164000
  • symbol: JSNZ_000385
  • pan gene symbol?: mpsB
  • synonym:
  • product: DUF2309 domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000385
  • symbol: JSNZ_000385
  • product: DUF2309 domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 414140..416845
  • length: 2706
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    ATGACAACACAGTTAAATATCAATTCAGTCATTGAAAATGCGAAACGTGTTATTACACCA
    TTATCACCGATTTCGATTTTTGCAGCACGAAATCCATGGGAAGGATTAGAAGCGGATACG
    TTTGAAGATGTCGCAAAATGGTTACGTGACGTTCGAGATGTGGATATTTTCCCAAATAAA
    GCATTAATAGAAAGCGCTGTGGCACGTGGTGAATTAGATGAAAGTGTCTTTAATCAACTT
    GTTACTGATATGTTACTTGAACATTACTACAATATCCCGCAACACTACATCAATCTTTAT
    ATTGATAACATTAAAACATTAAAAGACGTACCTGCATCATATATGGATCATTCAAATGTT
    GATGTTGTTGCTGATCTACTATTAGAAAAATCAAAACGTGATATGGCTGAATCATATCAT
    CACTATGATGTACGTCCGATGAGTGATGCAATAATAGATGAACAAGGTGAGCCACTTAGC
    GAACAAGTGAATCGTCAAATGATTAAATGGACGAAACTTTATATCGATCAATTTCTATCG
    AGTTGGACAATGCCGAAGCGTGAGCAAAGTTTTTACCATGCATGGTTGCATTTAGCGCAA
    CATGACCATAGTTTTACTAAAGCACAGCGCCAAGTGATTAAAGGCTTACCCAATGATCCT
    GAAATGACGATAGAGTCAGTATTAACTCATTTTTCAATAGATCAGGAAGACTACCAAGCT
    TATGTTGAAGGACATCTTTTGGCGTTACCGGGTTGGGCAGGTATGTTATATTACCGTTCA
    CAACAGCATCACTTTGAACAACATTTGTTAACGGATTATTTGGCAATTCGGTTAGTTGTC
    GAACAATTGCTAGTTGGTGATGAGTTTAAGTCAGTCACTAAAGATTGTGAAAGTAGATCG
    GAAAATTGGTTTAAGCAAACTGTTGCATCATGGTGTTACTACAGTGATATGCCTAGCGAT
    GTATTACTACAACATGACGTCCATGAAATTCAAACATTTATTCATTTTGCAGCAATTATG
    AATAAAAATGTATTTAAAAATTTATGGCTAATTGCCTGGGAAATGACATACGAATCTCAG
    TTAAAACAAAAAATTAAAGCAGGTCATGAAAGTGTGGCGGGCGCATTAGATGTAAACCAA
    GTAAATGTCTCAGAAAATGATAACGTTAATCAGCCACATTCAGTATTGTTAAATGACACA
    CAAGCAGTTGATGAAAATAATAGCGAGCTAAATCAGGCGGGCACATCAACGAAAGCGCAA
    ATTGCATTTTGTATAGATGTTCGTTCAGAACCATTTCGTAGACATATCGAAGCAGCAGGG
    CCCTTTGAAACGATTGGTATTGCAGGTTTCTTTGGATTACCTATTCAAAAAGATGCCGTC
    GACGAACAATTCAAACATGATTCATTACCTGTCATGGTACCGCCGGCATATCGCATTAAA
    GAATTTGCAGACCGCTACGATATGAATGTTTATCGACAACAGCAACAGACAATGTCATCG
    ATGTTTTACACATTTAAATTGATGAAAAATAATGTCATGCCTAGTCTGTTATTGCCTGAA
    TTAAGTGGGCCATTTTTAAGCTTGAGTACCATTGTCAATTCGATTATGCCTAGAAAAAGT
    CGCGCGTCTTTACAAAAAATAAAACAAAAATGGTTGAAAAAGCCTGAAACAAAGTTAACG
    ATTGATCGTGAGTTTGACCGAACATCAGGCTTACCTGTTGGATTTACTGAGCAAGAGCAA
    ATTGATTTCGCGTTACAAGCGTTGAAATTGATGGATTTAACCGAAGCATTTGCGCCGTTC
    GTTGTGTTAGCAGGTCATGCTAGTCATTCTCACAATAATCCACATCATGCATCACTTGAA
    TGTGGGGCTTGTGGTGGCGCATCAAGCGGTTTTAATGCTAAGTTATTAGCGATGATATGT
    AATCGTCCAAATGTCAGACAAGGATTAAAACAAGCAGGCGTGTATATTCCAGAGACAACT
    GTTTTTGCGGCAGCAGAACATCATACGTCTACTGATACGTTGGCATGGGTATATGTGCCA
    GACACATTATCAGCTTTAGCTCTAGATGCATATGAATCATTGAATGACGCGATGCCGATG
    ATTTCTGAACAAGCGAATCGCGAACGTTTGGACAAACTGCCAACGATTGGTCGTGTGAAT
    CATCCAGTGGAAGAAGCACAGCGGTTTGCAAGTGATTGGAGTGAGGTACGTCCAGAATGG
    GGCTTGGCTAAAAATGCATCATTTATAATTGGACGACGCCAATTAACAAAAGGCATTGAT
    TTAGAAGGGCGGACATTTTTACACAATTATGATTGGCGTAAAGATAAAGATGGCACATTA
    TTAAATACCATCATTTCTGGTCCGGCACTTGTGGCACAATGGATTAATTTACAATATTAT
    GCGTCGACAGTTGCGCCGCATTTTTACGGAAGTGGGAATAAAGTGACACAAACCGTCACG
    TCAGGTGTTGGTGTCATGCAAGGTAATGCGAGTGATCTGATGTATGGCTTATCATGGCAA
    TCTGTTATGGCTGCTGATCGAACGATGTATCATTCGCCAATTCGTTTGCTTGTCGTTATT
    CAGGCACCCGACTATGTTGTAGCTAGACTACTCGCGAATAATGAGCATTTCGCTAGGAAG
    GTGTCTAATCATTGGCTGCGTTTAATGAGCGTTAATGAGGAAGGGCATTTTAAAAGTTGG
    ATTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2706

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000385
  • symbol: JSNZ_000385
  • description: DUF2309 domain-containing protein
  • length: 901
  • theoretical pI: 6.09399
  • theoretical MW: 102559
  • GRAVY: -0.31465

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    no clan defined DabA; Probable inorganic carbon transporter subunit DabA (PF10070; HMM-score: 828.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.5343
    • Cytoplasmic Membrane Score: 0.4149
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0507
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.024395
    • TAT(Tat/SPI): 0.000633
    • LIPO(Sec/SPII): 0.002325
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTTQLNINSVIENAKRVITPLSPISIFAARNPWEGLEADTFEDVAKWLRDVRDVDIFPNKALIESAVARGELDESVFNQLVTDMLLEHYYNIPQHYINLYIDNIKTLKDVPASYMDHSNVDVVADLLLEKSKRDMAESYHHYDVRPMSDAIIDEQGEPLSEQVNRQMIKWTKLYIDQFLSSWTMPKREQSFYHAWLHLAQHDHSFTKAQRQVIKGLPNDPEMTIESVLTHFSIDQEDYQAYVEGHLLALPGWAGMLYYRSQQHHFEQHLLTDYLAIRLVVEQLLVGDEFKSVTKDCESRSENWFKQTVASWCYYSDMPSDVLLQHDVHEIQTFIHFAAIMNKNVFKNLWLIAWEMTYESQLKQKIKAGHESVAGALDVNQVNVSENDNVNQPHSVLLNDTQAVDENNSELNQAGTSTKAQIAFCIDVRSEPFRRHIEAAGPFETIGIAGFFGLPIQKDAVDEQFKHDSLPVMVPPAYRIKEFADRYDMNVYRQQQQTMSSMFYTFKLMKNNVMPSLLLPELSGPFLSLSTIVNSIMPRKSRASLQKIKQKWLKKPETKLTIDREFDRTSGLPVGFTEQEQIDFALQALKLMDLTEAFAPFVVLAGHASHSHNNPHHASLECGACGGASSGFNAKLLAMICNRPNVRQGLKQAGVYIPETTVFAAAEHHTSTDTLAWVYVPDTLSALALDAYESLNDAMPMISEQANRERLDKLPTIGRVNHPVEEAQRFASDWSEVRPEWGLAKNASFIIGRRQLTKGIDLEGRTFLHNYDWRKDKDGTLLNTIISGPALVAQWINLQYYASTVAPHFYGSGNKVTQTVTSGVGVMQGNASDLMYGLSWQSVMAADRTMYHSPIRLLVVIQAPDYVVARLLANNEHFARKVSNHWLRLMSVNEEGHFKSWI

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

Sonja Mayer, Wojtek Steffen, Julia Steuber, Friedrich Götz
The Staphylococcus aureus NuoL-like protein MpsA contributes to the generation of membrane potential.
J Bacteriol: 2015, 197(5);794-806
[PubMed:25448817] [WorldCat.org] [DOI] (I p)

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