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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_000577
  • pan locus tag?: SAUPAN002475000
  • symbol: JSNZ_000577
  • pan gene symbol?: —
  • synonym:
  • product: endonuclease III domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_000577
  • symbol: JSNZ_000577
  • product: endonuclease III domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 613179..613814
  • length: 636
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    ATGTTAGGAACTGATGAATTATATAAAGTTTTATATGAACATCTCGGACCACAATTTTGG
    TGGCCTGCTGATAATGACATTGAAATGATGTTAGGTGCAATTTTAGTTCAAAATACTAGA
    TGGCGAAATACAGAAATTGCATTGAATCAGATTAAAGAACATACGCATTTTAATCCAAAT
    CATATATTAGAACTACCTATTGAAACGTTACAATCATTGATACATTCAAGTGGCTTTTAT
    AAAAGTAAATCACTGACGATTAAAACATTATTAACATGGTTAGCACGACATCATTTCAAT
    TATCAAGAGATTAATGAGCGATATAAAGGTGGATTAAGAAAAGAATTATTATCTTTGAAA
    GGTATTGGAAGTGAAACAGCAGATGTCTTACTTGTTTATATATTCGGACGTATTGAATTT
    ATTCCAGATAGCTATACAAGAAAAATATATGATAAATTAGGATATGAAAACACTAAAAAT
    TATGATCAATTAAAAAAAGTAGTCACATTACCAAATCATTTTACAAATCAAGATGCTAAT
    GAATTTCATGCTCTGTTAGATGTATTTGGTAAACATTACTTTAGAGACAAAGATATAAAG
    AATTATGATTTTTTAGAACCTTACTTTAAAAAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    636

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_000577
  • symbol: JSNZ_000577
  • description: endonuclease III domain-containing protein
  • length: 211
  • theoretical pI: 7.4149
  • theoretical MW: 25046.4
  • GRAVY: -0.504265

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair endonuclease III (TIGR01083; EC 4.2.99.18; HMM-score: 47.6)
    and 1 more
    Genetic information processing DNA metabolism DNA replication, recombination, and repair 8-oxoguanine DNA-glycosylase (ogg) (TIGR00588; EC 3.2.2.-; HMM-score: 16.1)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    HHH (CL0198) HhH-GPD; HhH-GPD superfamily base excision DNA repair protein (PF00730; HMM-score: 34.5)
    and 1 more
    HHH; Helix-hairpin-helix motif (PF00633; HMM-score: 21.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9569
    • Cytoplasmic Membrane Score: 0.0335
    • Cell wall & surface Score: 0.0006
    • Extracellular Score: 0.009
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001339
    • TAT(Tat/SPI): 0.000113
    • LIPO(Sec/SPII): 0.000263
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNTEIALNQIKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK

⊟Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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