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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

organism: Staphylococcus aureus JSNZ
locus tag: JSNZ_000886
pan locus tag^?: SAUPAN003021000
symbol: JSNZ_000886
pan gene symbol^?: —
synonym:
product: bifunctional UDP-sugar hydrolase/5'-nucleotidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

type: CDS
locus tag: JSNZ_000886
symbol: JSNZ_000886
product: bifunctional UDP-sugar hydrolase/5'-nucleotidase
replicon: chromosome
strand: +
coordinates: 886260..887579
length: 1320
essential: unknown other strains

⊟Accession numbers[edit | edit source]

Gene ID:
RefSeq:
BioCyc:
MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
TTGAGGCTTACAATTTATCATACGAACGATATTCATAGTCATTTACATGAATACGAACGC
ATTAAAGCATATATGGCAGAACATCGGCCACGACTTAACCATCCTTCTTTATATGTTGAT
CTAGGTGATCATGTAGATTTATCCGCACCCATAACTGAAGCAACTTTAGGTAAAAAGAAT
GTGGCATTACTAAATGAAGCAAAATGTGATGTTGCAACAATCGGTAATAATGAAGGGATG
ACCATTTCACACGAAGCTTTAAATCACCTTTACGACGAAGCAAAATTTATAGTGACATGT
AGCAATGTTATAGATGAATCAGGTCATTTACCAAATAATATCGTTTCTTCTTATATTAAT
GACATAGACGGTGTGAAAATACTATTCGTTGCAGCGACAGCACCTTTTACCCCATTTTAT
CGTGCACTAAATTGGATTGTTACCGATCCACTTGAATCTATAAAAGAAGAAATTGAACTT
CAACGAGGTAAATTTGATGTATTAATCGTGCTAAGTCATTGTGGCATTTTCTTCGATGAA
ACATTATGCCAAGAATTGCCTGAAATTGATGTCATTTTTGGTAGTCATACGCATCATTAT
TTTGAACATGGTGAAATCAATAATGGTGTACTGATGGCGGCAGCTGGAAAGTATGGTAAT
TATCTTGGAGAGGTTAATTTAACTTTTGAGGCACATAAAGTAGTACATAAAACTGCAAAG
ATTATTCCTTTAGAAACATTACCTGAAGTTGAAACTTCATTTGAAGAAGAAGGAAAAACG
TTAATGTCCAATTCAGTAATTCAACATCCAGTAGTGCTTAAGCGTAGTATGAATCACATA
ACTGAAGCTGCATACTTATTAGCTCAAAGTGTTTGTGAGTATACACATGCACAATGTGCC
ATCATCAATGCTGGCTTACTCGTTAAAGATATTGTAAAAGATGAAGTGACAGAATATGAC
ATTCATCAAATGTTACCGCATCCGATTAATATGGTAAGGGTTAGACTTTCTGGTGTGAAA
TTAAAAGAGATTATAACTAAAAGTAATAAACAAGAATATATGTATGAACATGCACAAGGT
TTGGGTTTCAGAGGGAATATATTTGGAGGATATATTCTTTATAATTTAGGGTACATTCAT
TCTACAGGGCGTTACTATCTGAATGGAGAAGAAATCGAAGACGACAAAGAATATGTACTA
GGTACGATAGATATGTATACGTTCGGTCGTTATTTCCCAACATTGAAAGAATTACCAAAA
GAGTATTTAATGCCAGAGTTTTTAAGAGATATATTTAAAGAAAAATTATTGGAATATTAA
60
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1020
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1320

⊟Protein[edit | edit source]

⊟General[edit | edit source]

locus tag: JSNZ_000886
symbol: JSNZ_000886
description: bifunctional UDP-sugar hydrolase/5'-nucleotidase
length: 439
theoretical pI: 5.49146
theoretical MW: 50068.8
GRAVY: -0.17426

⊟Function[edit | edit source]

TIGRFAM:
thiosulfohydrolase SoxB (TIGR04486; HMM-score: 64.5)
and 2 more
Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Pyridine nucleotides NAD nucleotidase (TIGR01530; EC 3.1.3.5,3.6.1.22; HMM-score: 37.7)
Metabolism Transport and binding proteins Other NAD nucleotidase (TIGR01530; EC 3.1.3.5,3.6.1.22; HMM-score: 37.7)
TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
PFAM:
Calcineurin (CL0163) Metallophos; Calcineurin-like phosphoesterase (PF00149; HMM-score: 43.9)
NadN_C (CL0781) 5_nucleotid_C; 5'-nucleotidase, C-terminal domain (PF02872; HMM-score: 37.7)
and 1 more
Calcineurin (CL0163) PGA_cap; Bacterial capsule synthesis protein PGA_cap (PF09587; HMM-score: 18.5)

⊟Structure, modifications & cofactors[edit | edit source]

domains:
modifications:
cofactors:
effectors:

⊟Localization[edit | edit source]

PSORTb: Cellwall
- Cytoplasmic Score: 0.11
- Cytoplasmic Membrane Score: 0.02
- Cellwall Score: 8.97
- Extracellular Score: 0.9
- Internal Helices: 0
DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9875
- Cytoplasmic Membrane Score: 0.0116
- Cell wall & surface Score: 0.0001
- Extracellular Score: 0.0008
LocateP:
SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.007738
- TAT(Tat/SPI): 0.000201
- LIPO(Sec/SPII): 0.001555
predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

GI:
RefSeq:
UniProt:

⊟Protein sequence[edit | edit source]

MRLTIYHTNDIHSHLHEYERIKAYMAEHRPRLNHPSLYVDLGDHVDLSAPITEATLGKKNVALLNEAKCDVATIGNNEGMTISHEALNHLYDEAKFIVTCSNVIDESGHLPNNIVSSYINDIDGVKILFVAATAPFTPFYRALNWIVTDPLESIKEEIELQRGKFDVLIVLSHCGIFFDETLCQELPEIDVIFGSHTHHYFEHGEINNGVLMAAAGKYGNYLGEVNLTFEAHKVVHKTAKIIPLETLPEVETSFEEEGKTLMSNSVIQHPVVLKRSMNHITEAAYLLAQSVCEYTHAQCAIINAGLLVKDIVKDEVTEYDIHQMLPHPINMVRVRLSGVKLKEIITKSNKQEYMYEHAQGLGFRGNIFGGYILYNLGYIHSTGRYYLNGEEIEDDKEYVLGTIDMYTFGRYFPTLKELPKEYLMPEFLRDIFKEKLLEY

⊟Experimental data[edit | edit source]

experimentally validated: data available for NCTC8325
protein localization: data available for COL
quantitative data / protein copy number per cell:
interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

Operon-mapper ^[1] : JSNZ_000883 > JSNZ_000884 > JSNZ_000885 > JSNZ_000886 > lipA

⊟Regulation[edit | edit source]

regulator:

⊟Transcription pattern[edit | edit source]

S.aureus Expression Data Browser: data available for NCTC8325

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

Aureolib: no data available

⊟Protein stability[edit | edit source]

half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
Bioinformatics: 2018, 34(23);4118-4120
[PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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