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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001545
  • pan locus tag?: SAUPAN004135000
  • symbol: JSNZ_001545
  • pan gene symbol?: zur
  • synonym:
  • product: Fur family transcriptional regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001545
  • symbol: JSNZ_001545
  • product: Fur family transcriptional regulator
  • replicon: chromosome
  • strand: -
  • coordinates: 1581828..1582238
  • length: 411
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGAATACAAATGATGCTATTAAAATTTTAAAAGAGAACGGTTTAAAATATACAGATAAA
    CGTAAAGATATGTTAGATATTTTTGTCGAAGAAGATAAGTATATAAACGCAAAGTATATA
    CAACAAGTTATGGATGAAAATTATCCTGGAATTTCATTCGACACAATATATAGAAACCTG
    CACTTATTTAAAGATTTAGGGATTATTGAAAATACAGAACTTGATGGTGAAATGAAGTTT
    AGAATCGCTTGTACAAACCATCATCATCATCATTTTATCTGTGAAAAGTGTGGAGATACA
    AAGGTAATAGATTATTGTCCAATAGATCAGATAAAGTTATCACTACCTGGTGTTAATATT
    CACAAACACAAACTTGAAGTTTATGGTGTATGTGAGTCTTGCCAAGATTAA
    60
    120
    180
    240
    300
    360
    411

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001545
  • symbol: JSNZ_001545
  • description: Fur family transcriptional regulator
  • length: 136
  • theoretical pI: 6.07084
  • theoretical MW: 15922.1
  • GRAVY: -0.516912

⊟Function[edit | edit source]

  • TIGRFAM:
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    HTH (CL0123) FUR; Ferric uptake regulator family (PF01475; HMM-score: 114)
    and 3 more
    MJ1010-like_2nd; Uncharacterized ATP-binding protein MJ1010-like, C-terminal domain (PF21690; HMM-score: 14.4)
    NSUN_ferredox (CL0795) NSUN5_fdxn-like; NOL1/NOP2/Sun domain family member 5, ferredoxin-like domain (PF21148; HMM-score: 13.6)
    no clan defined F-protein; Negative factor, (F-Protein) or Nef (PF00469; HMM-score: 12.6)

⊟Structure, modifications & cofactors[edit | edit source]

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8523
    • Cytoplasmic Membrane Score: 0.0001
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.1475
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002478
    • TAT(Tat/SPI): 0.000134
    • LIPO(Sec/SPII): 0.000435
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNTNDAIKILKENGLKYTDKRKDMLDIFVEEDKYINAKYIQQVMDENYPGISFDTIYRNLHLFKDLGIIENTELDGEMKFRIACTNHHHHHFICEKCGDTKVIDYCPIDQIKLSLPGVNIHKHKLEVYGVCESCQD

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization: data available for COL
  • quantitative data / protein copy number per cell: data available for COL
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: Zur* (repression) regulon
    Zur*(TF)important in Zinc homeostasis;  regulation predicted or transferred from N315 and NCTC 8325  [2]

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)
  2. ↑ Hannes Wolfgramm, Larissa Milena Busch, Jöran Tebben, Henry Mehlan, Lisa Hagenau, Thomas Sura, Tilly Hoffmüller, Elisa Bludau, Manuela Gesell Salazar, Alexander Reder, Stephan Michalik, Leif Steil, Kristin Surmann, Ulrike Mäder, Silva Holtfreter, Uwe Völker
    Integrated genomic and proteomic analysis of the mouse-adapted Staphylococcus aureus strain JSNZ.
    Curr Res Microb Sci: 2025, 9;100489
    [PubMed:41146725] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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