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FunGene: 08-OCT-2024

⊟Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001644
  • pan locus tag?: SAUPAN004262000
  • symbol: radC
  • pan gene symbol?: radC
  • synonym:
  • product: DNA repair protein RadC

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001644
  • symbol: radC
  • product: DNA repair protein RadC
  • replicon: chromosome
  • strand: -
  • coordinates: 1677153..1677839
  • length: 687
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    TTGAAAATTAAAGAAATGGTAACTTCAGAAATGCCAAGAGAACGTTTGTTAAGCCATGGT
    GCAAAAAGTCTTTCGAATACAGAATTATTAGCTATATTAATTAACACTGGAAGAAAAGGA
    TTCTCGAGCATAGACATTAGTAATGAACTGCTTAAATCTGCTTCGAATCTGAATGAATTG
    AAAAAATCTTCAATTAACGATTTGATACAAGTTAAAGGGATTGGATTACAAAAAGCAATT
    ACTTTAAAAGCAGCATTTGAGTTAGGGGAAAGGATGGGGAGAAGAGCTGAAAATAATCGT
    ATAAAAATAACGCAACCAAGTGATGTTGCTGATTATATGATTCCAACAATGAAAGATTTA
    ACACAAGAACATTTTGTCATTTTATTGTTAAATTCAAAAAATGTAGTGATTAAAGAAACC
    TGTGTTTTTAAAGGTACATTAAATAGTTCGATTGTACATCCACGTGAAATTTTTAGTATT
    GCGGTGAGAGAAAATGCCAATGCAATCATCGCAGTTCATAATCATCCATCCGGTGATGTA
    ACGCCCTCACAAGAAGATATCATAACAACAATGAGGTTGAAGGAGTGTGGTTTGATTTTA
    GGGATAGATTTATTGGATCATATTATAATCGGTGATAATAGATTTACCAGTCTTGTAGAA
    GCGGGTTACTTTGATGAAAATGATTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    687

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: JSNZ_001644
  • symbol: RadC
  • description: DNA repair protein RadC
  • length: 228
  • theoretical pI: 6.79858
  • theoretical MW: 25311.1
  • GRAVY: -0.105702

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA repair protein RadC (TIGR00608; HMM-score: 233.7)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    JAB (CL0366) RadC; RadC-like JAB domain (PF04002; HMM-score: 156.4)
    and 5 more
    HHH (CL0198) UPF0758_N; UPF0758 N-terminal (PF20582; HMM-score: 88.3)
    HHH_2; Helix-hairpin-helix motif (PF12826; HMM-score: 16.4)
    HHH_5; Helix-hairpin-helix domain (PF14520; HMM-score: 15)
    JAB (CL0366) Prok-JAB; Prokaryotic homologs of the JAB domain (PF14464; HMM-score: 14.2)
    TPR (CL0020) Cohesin_load; Cohesin loading factor (PF10345; HMM-score: 13.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9744
    • Cytoplasmic Membrane Score: 0.0047
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0206
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.009685
    • TAT(Tat/SPI): 0.003204
    • LIPO(Sec/SPII): 0.00124
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKIKEMVTSEMPRERLLSHGAKSLSNTELLAILINTGRKGFSSIDISNELLKSASNLNELKKSSINDLIQVKGIGLQKAITLKAAFELGERMGRRAENNRIKITQPSDVADYMIPTMKDLTQEHFVILLLNSKNVVIKETCVFKGTLNSSIVHPREIFSIAVRENANAIIAVHNHPSGDVTPSQEDIITTMRLKECGLILGIDLLDHIIIGDNRFTSLVEAGYFDEND

⊟Experimental data[edit | edit source]

  • experimentally validated: data available for COL, NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription pattern[edit | edit source]

⊟Protein synthesis (provided by Aureolib)[edit | edit source]

⊟Protein stability[edit | edit source]

  • half-life: no data available

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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