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FunGene: 08-OCT-2024

Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_001772
  • pan locus tag?: SAUPAN004482000
  • symbol: crcB
  • pan gene symbol?: crcB1
  • synonym:
  • product: fluoride efflux transporter CrcB

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_001772
  • symbol: crcB
  • product: fluoride efflux transporter CrcB
  • replicon: chromosome
  • strand: +
  • coordinates: 1824011..1824376
  • length: 366
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    ATGCAATATGTATATATTTTTATCGGTGGTGCTTTAGGCGCTTTATTACGTTACCTCATT
    TCTTTTCTGAATACTGACGGAGGTTTTCCAATCGGAACACTGATAGCCAATTTGACTGGT
    GCCTTTGTAATGGGATTGCTAACAGCCTTAACAATTGCATTTTTTTCAAACCATCCGACC
    CTAAAAAAAGCTATTACGACTGGTTTTCTTGGTGCTTTAACGACTTTTTCAACATTTCAA
    TTAGAATTAATACATATGTTTGATCATCAACAATTTATAACTTTACTACTATATGCTGTA
    ACAAGTTATGTCTTGGGTATTTTGTTATGTTACGTCGGTATAAAACTAGGTGGTGGTTTA
    TCATGA
    60
    120
    180
    240
    300
    360
    366

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: JSNZ_001772
  • symbol: CrcB
  • description: fluoride efflux transporter CrcB
  • length: 121
  • theoretical pI: 8.4518
  • theoretical MW: 13061.5
  • GRAVY: 1.00992

Function[edit | edit source]

  • TIGRFAM:
    Unknown function General protein CrcB (TIGR00494; HMM-score: 86)
  • TheSEED: data available for COL, N315, NCTC8325, Newman
  • PFAM:
    DMT (CL0184) CRCB; CrcB-like protein, Camphor Resistance (CrcB) (PF02537; HMM-score: 102.3)
    and 4 more
    no clan defined DUF6114; Family of unknown function (DUF6114) (PF19609; HMM-score: 12.5)
    Holin-III (CL0564) Phage_holin_3_3; LydA holin phage, holin superfamily III (PF16083; HMM-score: 12.1)
    no clan defined DUF5676; 2TM family of unknown function (DUF5676) (PF18926; HMM-score: 11.4)
    DUF2070; Predicted membrane protein (DUF2070) (PF09843; HMM-score: 5.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 4
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.001
    • Cytoplasmic Membrane Score: 0.9984
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0005
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.015512
    • TAT(Tat/SPI): 0.000294
    • LIPO(Sec/SPII): 0.004469
  • predicted transmembrane helices (TMHMM): 4

Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

Protein sequence[edit | edit source]

  • MQYVYIFIGGALGALLRYLISFLNTDGGFPIGTLIANLTGAFVMGLLTALTIAFFSNHPTLKKAITTGFLGALTTFSTFQLELIHMFDHQQFITLLLYAVTSYVLGILLCYVGIKLGGGLS

Experimental data[edit | edit source]

  • experimentally validated:
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

  1. Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

Relevant publications[edit | edit source]