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FunGene: 08-OCT-2024

Summary[edit | edit source]

  • organism: Staphylococcus aureus JSNZ
  • locus tag: JSNZ_002444
  • pan locus tag?: SAUPAN006029000
  • symbol: cntL
  • pan gene symbol?: cntL
  • synonym:
  • product: D-histidine (S)-2-aminobutanoyltransferase CntL

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: JSNZ_002444
  • symbol: cntL
  • product: D-histidine (S)-2-aminobutanoyltransferase CntL
  • replicon: chromosome
  • strand: -
  • coordinates: 2445817..2446635
  • length: 819
  • essential: unknown other strains

Accession numbers[edit | edit source]

  • Gene ID:
  • RefSeq:
  • BioCyc:
  • MicrobesOnline:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGAATAACTTTAATAATGAAATCAAATTGATATTACAACAATATTTAGAAAAGTTTGAA
    GCGCATTACGAGCGTGTATTACAAGACGATCAATATATCGAAGCATTAGAAACATTGATG
    GATGACTATAGTGAATTTATTTTAAATCCTATTTATGAACAACAATTTAATGCTTGGCGT
    GACGTTGAAGAAAAAGCACAATTAATAAAATCACTGCAATATATTACAGCGCAGTGTGTT
    AAACAAGTGGAAGTCATTAGAGCTAGACGTCTATTAGACGGACAGGCGTCTACCACAGGT
    TACTTTGACAATATAGAACATTGTATTGATGAAGAGTTTGGACAATGTAGTATAGCTAGC
    AATGACAAAGTATTGTTAGTTGGTTCAGGTGCATATCCAATGACGTTAATTCAAGTAGCA
    AAAGAAACAGGTGCTTCAGTTATCGGTATTGATATTGATCCACAAGCCGTTGACCTAGGG
    CGCAGAATCGTTAACGTCTTAGCACCAAATGAAGATATAACAATTACGGATCAAAAGGTA
    TCTGAACTTAAAGATATCAAAGATGTGACGCATATCATATTCAGCTCGACAATTCCTTTA
    AAGTACAGCATTTTAGAAGAATTATATGATTTAACAAATGAAAATGTCGTAGTTGCAATG
    CGCTTTGGTGATGGCATCAAAGCAATATTTAATTATCCGTCACAAGAAACAGCGGAAGAT
    AAGTGGCAATGTGTGAATAAACATATGAGACCACAGCAAATTTTTGATATAGCACTTTAT
    AAAAAAGCAGCTATAAAGGTAGGTATTACGGATGTCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    819

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: JSNZ_002444
  • symbol: CntL
  • description: D-histidine (S)-2-aminobutanoyltransferase CntL
  • length: 272
  • theoretical pI: 4.37556
  • theoretical MW: 31082.1
  • GRAVY: -0.211397

Function[edit | edit source]

  • TIGRFAM:
    6-hydroxycyclohex-1-ene-1-carbonyl-CoA dehydrogenase (TIGR03201; EC 1.1.1.-; HMM-score: 22.7)
    and 7 more
    Unknown function Enzymes of unknown specificity putative methylase (TIGR00537; HMM-score: 15.1)
    T-complex protein 1, theta subunit (TIGR02346; HMM-score: 14.9)
    Genetic information processing Protein synthesis Ribosomal proteins: synthesis and modification ribosomal protein L11 methyltransferase (TIGR00406; EC 2.1.1.-; HMM-score: 14.1)
    2-aminoethylphosphonate aminotransferase (TIGR03301; EC 2.6.1.-; HMM-score: 13.3)
    putative phosphonate catabolism associated alcohol dehydrogenase (TIGR03366; HMM-score: 12.7)
    methyltransferase, Rta_06860 family (TIGR04290; EC 2.1.1.-; HMM-score: 12.2)
    methyltransferase, FxLD system (TIGR04364; HMM-score: 11.5)
  • TheSEED: data available for COL, N315, NCTC8325, Newman, USA300_FPR3757
  • PFAM:
    NADP_Rossmann (CL0063) NAS; Nicotianamine synthase protein (PF03059; HMM-score: 18)
    Methyltransf_31; Methyltransferase domain (PF13847; HMM-score: 17)
    no clan defined DUF5856; Family of unknown function (DUF5856) (PF19174; HMM-score: 16.4)
    NADP_Rossmann (CL0063) Methyltransf_25; Methyltransferase domain (PF13649; HMM-score: 16.3)
    no clan defined OVT1; Major antigen, helical domain (PF24423; HMM-score: 14.6)
    and 2 more
    NADP_Rossmann (CL0063) ADH_zinc_N; Zinc-binding dehydrogenase (PF00107; HMM-score: 13.6)
    AlaDh_PNT_C; Alanine dehydrogenase/PNT, C-terminal domain (PF01262; HMM-score: 12.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8493
    • Cytoplasmic Membrane Score: 0.1402
    • Cell wall & surface Score: 0.0018
    • Extracellular Score: 0.0087
  • LocateP:
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001139
    • TAT(Tat/SPI): 0.000084
    • LIPO(Sec/SPII): 0.000189
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq:
  • UniProt:

Protein sequence[edit | edit source]

  • MNNFNNEIKLILQQYLEKFEAHYERVLQDDQYIEALETLMDDYSEFILNPIYEQQFNAWRDVEEKAQLIKSLQYITAQCVKQVEVIRARRLLDGQASTTGYFDNIEHCIDEEFGQCSIASNDKVLLVGSGAYPMTLIQVAKETGASVIGIDIDPQAVDLGRRIVNVLAPNEDITITDQKVSELKDIKDVTHIIFSSTIPLKYSILEELYDLTNENVVVAMRFGDGIKAIFNYPSQETAEDKWQCVNKHMRPQQIFDIALYKKAAIKVGITDV

Experimental data[edit | edit source]

  • experimentally validated: data available for NCTC8325
  • protein localization:
  • quantitative data / protein copy number per cell:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription pattern[edit | edit source]

Protein synthesis (provided by Aureolib)[edit | edit source]

Protein stability[edit | edit source]

  • half-life: no data available

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

  1. Blanca Taboada, Karel Estrada, Ricardo Ciria, Enrique Merino
    Operon-mapper: a web server for precise operon identification in bacterial and archaeal genomes.
    Bioinformatics: 2018, 34(23);4118-4120
    [PubMed:29931111] [WorldCat.org] [DOI] (I p)

Relevant publications[edit | edit source]